ras Proteins

"ras Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47.

Descriptor ID	D018631
MeSH Number(s)	D08.811.277.040.330.300.400.500 D12.644.360.525.500 D12.776.157.325.515.500 D12.776.476.525.500
Concept/Terms	ras Proteins ras Proteins ras GTPases GTPases, ras Gene Products, ras ras Gene Products

Below are MeSH descriptors whose meaning is more general than "ras Proteins".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
ras Proteins [D08.811.277.040.330.300.400.500]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Monomeric GTP-Binding Proteins [D12.644.360.525]
ras Proteins [D12.644.360.525.500]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Monomeric GTP-Binding Proteins [D12.776.157.325.515]
ras Proteins [D12.776.157.325.515.500]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Monomeric GTP-Binding Proteins [D12.776.476.525]
ras Proteins [D12.776.476.525.500]

Below are MeSH descriptors whose meaning is related to "ras Proteins".

Below are MeSH descriptors whose meaning is more specific than "ras Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "ras Proteins" by people in this website by year, and whether "ras Proteins" was a major or minor topic of these publications.

Bar chart showing 43 publications over 18 distinct years, with a maximum of 5 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1998	1	1	2
2000	2	0	2
2002	2	1	3
2003	1	1	2
2005	4	1	5
2006	2	1	3
2007	2	0	2
2008	1	2	3
2009	1	0	1
2010	3	0	3
2011	2	0	2
2012	1	3	4
2013	1	1	2
2014	2	1	3
2015	1	1	2
2019	1	1	2
2020	0	1	1

Below are the most recent publications written about "ras Proteins" by people in Profiles.

Noreen Z, Loffredo CA, Bhatti A, Simhadri JJ, Nunlee-Bland G, Nnanabu T, John P, Khan JS, Ghosh S. Transcriptional Profiling and Biological Pathway(s) Analysis of Type 2 Diabetes Mellitus in a Pakistani Population. Int J Environ Res Public Health. 2020 08 13; 17(16).

View in: PubMed
Santiago-Cartagena E, Gonz?lez-Crespo S, V?lez V, Mart?nez N, Snider J, Jessulat M, Aoki H, Minic Z, Akamine P, Mej?as I, P?rez LM, Rymond BC, Babu M, Stagljar I, Rodr?guez-Medina JR. Identification and Functional Testing of Novel Interacting Protein Partners for the Stress Sensors Wsc1p and Mid2p of Saccharomyces cerevisiae. G3 (Bethesda). 2019 04 09; 9(4):1085-1102.

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V?lez-Segarra V, Carrasquillo-Carri?n K, Santini-Gonz?lez JJ, Ramos-Valerio YA, V?zquez-Qui?ones LE, Roche-Lima A, Rodr?guez-Medina JR, Par?s-Matos EI. Modelling and molecular docking studies of the cytoplasmic domain of Wsc-family, full-length Ras2p, and therapeutic antifungal compounds. Comput Biol Chem. 2019 Feb; 78:338-352.

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P?ron J, Mercier F, Tuech JJ, Younan R, Sideris L, Gelli M, Dumont F, Le Roy B, Sgarbura O, Lo Dico R, Bibeau F, Glehen O, Passot G. The location of the primary colon cancer has no impact on outcomes in patients undergoing cytoreductive surgery for peritoneal metastasis. Surgery. 2019 02; 165(2):476-484.

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Saqcena M, Patel D, Menon D, Mukhopadhyay S, Foster DA. Apoptotic effects of high-dose rapamycin occur in S-phase of the cell cycle. Cell Cycle. 2015; 14(14):2285-92.

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Javadov S, Escobales N. The Role of SIRT3 in Mediating Cardioprotective Effects of RAS Inhibition on Cardiac Ischemia-Reperfusion. J Pharm Pharm Sci. 2015; 18(3):547-50.

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Ashktorab H, Daremipouran M, Devaney J, Varma S, Rahi H, Lee E, Shokrani B, Schwartz R, Nickerson ML, Brim H. Identification of novel mutations by exome sequencing in African American colorectal cancer patients. Cancer. 2015 Jan 01; 121(1):34-42.

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Yellen P, Foster DA. Inhibition of fatty acid synthase induces pro-survival Akt and ERK signaling in K-Ras-driven cancer cells. Cancer Lett. 2014 Oct 28; 353(2):258-63.

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Salloum D, Mukhopadhyay S, Tung K, Polonetskaya A, Foster DA. Mutant ras elevates dependence on serum lipids and creates a synthetic lethality for rapamycin. Mol Cancer Ther. 2014 Mar; 13(3):733-41.

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Ruiz-Candelaria Y, Miranda-Diaz C, Hunter-Mellado RF. K-RAS mutation profile in Puerto Rican patients with colorectal cancer: trends from April 2009 to January 2011. Int J Biol Markers. 2013 Dec 17; 28(4):e393-7.

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