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Antonio Baines

TitleAssociate Professor
Faculty RankAssociate Professor
InstitutionNorth Carolina Central University
DepartmentBiological and Biomedical Sciences
Address700 George Street
Durham NC 27707
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    Collapse Research 
    Collapse research activities and funding
    SC2CA137845     (BAINES, ANTONIO THOMAS)Aug 1, 2008 - Jul 31, 2012
    NIH
    The Role of Pim Kinases as a Novel Molecular Target in Pancreatic Cancer
    Role: Principal Investigator
    R25ES031870     (JASPERS, ILONA)May 13, 2020 - Feb 28, 2025
    NIH
    21st Century Environmental Health Scholars: Increasing Diversity in Environmental Health Sciences Through Mentored Research Experiences (21EH Scholars)
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ingle K, LaComb JF, Graves LM, Baines AT, Bialkowska AB. AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor. PLoS One. 2023; 18(11):e0294065. PMID: 37943821.
      Citations: 1     Fields:    Translation:HumansCells
    2. Krulikas LJ, McDonald IM, Lee B, Okumu DO, East MP, Gilbert TSK, Herring LE, Golitz BT, Wells CI, Axtman AD, Zuercher WJ, Willson TM, Kireev D, Yeh JJ, Johnson GL, Baines AT, Graves LM. Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth. SLAS Discov. 2018 09; 23(8):850-861. PMID: 29742358.
      Citations: 8     Fields:    Translation:HumansCells
    3. Baines AT, Martin PM, Rorie CJ. Current and Emerging Targeting Strategies for Treatment of Pancreatic Cancer. Prog Mol Biol Transl Sci. 2016; 144:277-320. PMID: 27865460.
      Citations: 3     Fields:    Translation:HumansAnimals
    4. Xu D, Cobb MG, Gavilano L, Witherspoon SM, Williams D, White CD, Taverna P, Bednarski BK, Kim HJ, Baldwin AS, Baines AT. Inhibition of oncogenic Pim-3 kinase modulates transformed growth and chemosensitizes pancreatic cancer cells to gemcitabine. Cancer Biol Ther. 2013 Jun; 14(6):492-501. PMID: 23760491.
      Citations: 15     Fields:    Translation:HumansCells
    5. Baines AT, Xu D, Der CJ. Inhibition of Ras for cancer treatment: the search continues. Future Med Chem. 2011 Oct; 3(14):1787-808. PMID: 22004085.
      Citations: 181     Fields:    Translation:HumansCells
    6. Xu D, Allsop SA, Witherspoon SM, Snider JL, Yeh JJ, Fiordalisi JJ, White CD, Williams D, Cox AD, Baines AT. The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells. Carcinogenesis. 2011 Apr; 32(4):488-95. PMID: 21262926.
      Citations: 27     Fields:    Translation:HumansCells
    7. Rybarczyk BJ, Baines AT, McVey M, Thompson JT, Wilkins H. A case-based approach increases student learning outcomes and comprehension of cellular respiration concepts. Biochem Mol Biol Educ. 2007 May; 35(3):181-6. PMID: 21591085.
      Citations: 6     Fields:    
    8. Baines AT, Lim KH, Shields JM, Lambert JM, Counter CM, Der CJ, Cox AD. Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and ras effector expression to human tumor cell growth. Methods Enzymol. 2006; 407:556-74. PMID: 16757353.
      Citations: 12     Fields:    Translation:HumansCells
    9. Lim KH, Baines AT, Fiordalisi JJ, Shipitsin M, Feig LA, Cox AD, Der CJ, Counter CM. Activation of RalA is critical for Ras-induced tumorigenesis of human cells. Cancer Cell. 2005 Jun; 7(6):533-45. PMID: 15950903.
      Citations: 185     Fields:    Translation:HumansAnimalsCells
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