Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts.

Artaza JN, Singh R, Ferrini MG, Braga M, Tsao J, Gonzalez-Cadavid NF. Myostatin promotes a fibrotic phenotypic switch in multipotent C3H 10T1/2 cells without affecting their differentiation into myofibroblasts. J Endocrinol. 2008 Feb; 196(2):235-49.

View in: PubMed

subject areas

Animals
Cell Differentiation
Cell Line
Down-Regulation
Fibroblasts
Fibrosis
Follistatin
Gene Expression Regulation
Mesoderm
Mice
Multipotent Stem Cells
Myoblasts
Myostatin
Phenotype
Phosphorylation
Recombinant Proteins
RNA, Messenger
RNA, Small Interfering
Signal Transduction
Smad Proteins
Time Factors
Transforming Growth Factor beta
Transforming Growth Factor beta1
Up-Regulation

authors with profiles

Monica Gabriela Ferrini, PhD
Nestor F. Gonzalez-Cadavid, PhD
Jorge N. Artaza, PhD
Rajan Singh, PhD

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