"Myostatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A growth differentiation factor that is a potent inhibitor of SKELETAL MUSCLE growth. It may play a role in the regulation of MYOGENESIS and in muscle maintenance during adulthood.
| Descriptor ID |
D055435
|
| MeSH Number(s) |
D12.644.276.954.300.925 D12.776.467.942.300.925 D23.529.942.300.925
|
| Concept/Terms |
Myostatin- Myostatin
- Growth Differentiation Factor 8
- GDF-8
|
Below are MeSH descriptors whose meaning is more general than "Myostatin".
Below are MeSH descriptors whose meaning is more specific than "Myostatin".
This graph shows the total number of publications written about "Myostatin" by people in this website by year, and whether "Myostatin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2013 | 3 | 0 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Myostatin" by people in Profiles.
-
Wetzlich B, Nyakundi BB, Yang J. Therapeutic applications and challenges in myostatin inhibition for enhanced skeletal muscle mass and functions. Mol Cell Biochem. 2025 Mar; 480(3):1535-1553.
-
Mishra R, Jha R, Mishra B, Kim YS. Maternal immunization against myostatin suppresses post-hatch chicken growth. PLoS One. 2022; 17(10):e0275753.
-
Pervin S, Reddy ST, Singh R. Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-? Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders. Front Endocrinol (Lausanne). 2021; 12:653179.
-
Li B, Cui W, Yang J. Enhanced skeletal muscle growth in myostatin-deficient transgenic pigs had improved glucose uptake in stretozotocin-induced diabetes. Transgenic Res. 2020 04; 29(2):253-261.
-
Pervin S, Singh V, Tucker A, Collazo J, Singh R. Modulation of transforming growth factor-?/follistatin signaling and white adipose browning: therapeutic implications for obesity related disorders. Horm Mol Biol Clin Investig. 2017 Sep 09; 31(2).
-
Kovanecz I, Masouminia M, Gelfand R, Vernet D, Rajfer J, Gonzalez-Cadavid NF. Myostatin, a profibrotic factor and the main inhibitor of striated muscle mass, is present in the penile and vascular smooth muscle. Int J Impot Res. 2017 Sep; 29(5):194-201.
-
Covington JD, Tam CS, Bajpeyi S, Galgani JE, Noland RC, Smith SR, Redman LM, Ravussin E. Myokine Expression in Muscle and Myotubes in Response to Exercise Stimulation. Med Sci Sports Exerc. 2016 Mar; 48(3):384-90.
-
Lee SB, Kim JH, Jin DH, Jin HJ, Kim YS. Myostatin inhibitory region of fish (Paralichthys olivaceus) myostatin-1 propeptide. Comp Biochem Physiol B Biochem Mol Biol. 2016 Apr-May; 194-195:65-70.
-
Miao Y, Yang J, Xu Z, Jing L, Zhao S, Li X. RNA sequencing identifies upregulated kyphoscoliosis peptidase and phosphatidic acid signaling pathways in muscle hypertrophy generated by transgenic expression of myostatin propeptide. Int J Mol Sci. 2015 Apr 09; 16(4):7976-94.
-
Lee SB, Choi R, Park SK, Kim YS. Production of bioactive chicken follistatin315 in Escherichia coli. Appl Microbiol Biotechnol. 2014 Dec; 98(24):10041-51.