Cell Differentiation

"Cell Differentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Descriptor ID	D002454
MeSH Number(s)	G04.152
Concept/Terms	Cell Differentiation Cell Differentiation Differentiation, Cell Cell Differentiations Differentiations, Cell

Below are MeSH descriptors whose meaning is more general than "Cell Differentiation".

Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Differentiation [G04.152]

Below are MeSH descriptors whose meaning is related to "Cell Differentiation".

Below are MeSH descriptors whose meaning is more specific than "Cell Differentiation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cell Differentiation" by people in this website by year, and whether "Cell Differentiation" was a major or minor topic of these publications.

Bar chart showing 490 publications over 30 distinct years, with a maximum of 33 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	1	5	6
1998	1	6	7
1999	1	4	5
2000	2	5	7
2001	1	7	8
2002	5	11	16
2003	3	18	21
2004	3	17	20
2005	5	18	23
2006	4	10	14
2007	8	12	20
2008	4	19	23
2009	7	9	16
2010	4	15	19
2011	12	21	33
2012	5	14	19
2013	3	23	26
2014	6	17	23
2015	6	16	22
2016	8	13	21
2017	6	14	20
2018	5	21	26
2019	6	12	18
2020	6	18	24
2021	4	16	20
2022	0	8	8
2023	0	8	8
2024	4	8	12
2025	1	2	3

Below are the most recent publications written about "Cell Differentiation" by people in Profiles.

Alsaati N, Beigel K, Maurer K, Henrickson SE, Knight M, Green A, Giunta V, McGinn DE, Wang B, Crowley TB, McDonald-McGinn DM, Sullivan KE. Follicular Helper T Cells and B Cell Maturation in Patients with 22q11.2 Deletion Syndrome and Recurrent Infections. J Clin Immunol. 2026 Feb 03; 46(1):20.

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Shi X, Yan G, Zhao NC, Wang Q, Lu D, Lawler D, Gahtani RM, Byrne C, Haddad BR, Copeland RL, Martin MB. Calcium and Cadmium Activate ESRRB to Mediate Cell Stemness and Pluripotency. Int J Mol Sci. 2025 Dec 25; 27(1).

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Jordan Z, Singh A, Kattapong-Graber S, Goswami S, Sanjana NE, Zuccaro E, Zhang F, Eggan K, Hsieh J, Hermann BP, Hebert JM, Maroof AM. The Specification and Functional Maturation of Sub-Cerebral Projection Neurons Derived from Human Induced Pluripotent Stem Cells. Stem Cells Dev. 2025 12; 34(23-24):514-528.

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Kim S, Pajarillo E, Digman A, Ajayi I, Son DS, Aschner M, Lee E. CAD (Cath. a-Differentiated) Cells Produce Dopamine along with Dopamine-Synthesizing Enzymes. Neurochem Res. 2025 Jul 16; 50(4):233.

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Meyer-Acosta KK, Diaz-Guerra E, Varma P, Aruk A, Mirsadeghi S, Muniz-Perez A, Rafati Y, Hosseini A, Nieto-Estevez V, Giugliano M, Navara C, Hsieh J. APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoids. Stem Cell Reports. 2025 Jul 08; 20(7):102537.

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Brooks EP, Casey MR, Wells KL, Liu TY, Van Orman M, Sussel L. NKX2.2 and KLF4 cooperate to regulate a-cell identity. Genes Dev. 2025 02 03; 39(3-4):242-260.

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Magdaleno C, Tschumperlin DJ, Rajasekaran N, Varadaraj A. SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis. Sci Rep. 2024 12 30; 14(1):31855.

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Matsushige C, Kitazumi K, Beaman A, Miyagi M, Tallquist MD, Yamazaki Y. RGD peptide promotes follicle growth through integrins av?3/av?5 in three-dimensional culture. Reproduction. 2025 01 01; 169(1).

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Thombare K, Vaid R, Pucci P, Ihrmark Lundberg K, Ayyalusamy R, Baig MH, Mendez A, Burgos-Panadero R, H?ppner S, Bartenhagen C, Sj?vall D, Rehan AA, Dattatraya Nale S, Djos A, Martinsson T, Jaako P, Dong JJ, Kogner P, Johnsen JI, Fischer M, Turner SD, Mondal T. METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma. EMBO J. 2024 Dec; 43(24):6310-6335.

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Douvaras P, Buenaventura DF, Sun B, Lepack A, Baker E, Simpson E, Ebel M, Lallos G, LoSchiavo D, Stitt N, Adams N, McAuliffe C, Forton-Juarez A, Kosmyna B, Pereira E, Burnett B, Dilworth D, Fisher S, Wang J, Tonge P, Tomishima M, Paladini C, Wilkinson D, Soh CL, Srinivas M, Patsch C, Irion S. Ready-to-use iPSC-derived microglia progenitors for the treatment of CNS disease in mouse models of neuropathic mucopolysaccharidoses. Nat Commun. 2024 09 16; 15(1):8132.

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