Cell Polarity

"Cell Polarity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains.

Descriptor ID	D016764
MeSH Number(s)	G04.250
Concept/Terms	Cell Polarity Cell Polarity Cell Polarities Polarities, Cell Polarity, Cell

Below are MeSH descriptors whose meaning is more general than "Cell Polarity".

Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Polarity [G04.250]

Below are MeSH descriptors whose meaning is related to "Cell Polarity".

Below are MeSH descriptors whose meaning is more specific than "Cell Polarity".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cell Polarity" by people in this website by year, and whether "Cell Polarity" was a major or minor topic of these publications.

Bar chart showing 41 publications over 22 distinct years, with a maximum of 4 publications in 2017 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2002	1	0	1
2003	1	1	2
2004	1	2	3
2005	2	1	3
2006	1	1	2
2007	0	1	1
2008	0	1	1
2010	2	1	3
2011	1	1	2
2012	0	1	1
2013	1	2	3
2014	1	1	2
2015	0	1	1
2016	0	1	1
2017	0	4	4
2018	2	2	4
2020	1	1	2
2021	1	0	1
2022	1	0	1
2024	0	1	1
2025	1	0	1

Below are the most recent publications written about "Cell Polarity" by people in Profiles.

Fu W, Wang X, Rafiq M, Shao H, Wang C, Wang D, Tao C, Fu C, Zieger B, Liu X, Yao X, Zhang L. Multivalent interactions of Septin 6 promote the establishment of epithelial cell polarity. J Mol Cell Biol. 2025 Jun 28; 17(1).

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Wu L, Liu Y, He Q, Ao G, Xu N, He W, Liu X, Huang L, Yu Q, Kanamaru H, Dong S, Zhu S, Yuan Y, Han M, Ling Y, Liu L, Wu C, Zhou Y, Sherchan P, Flores JJ, Tang J, Chen X, He X, Zhang JH. PEDF-34 attenuates neurological deficit and suppresses astrocyte-dependent neuroinflammation by modulating astrocyte polarization via 67LR/JNK/STAT1 signaling pathway after subarachnoid hemorrhage in rats. J Neuroinflammation. 2024 Jul 21; 21(1):178.

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Alarcon VB, Marikawa Y. Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling. Reproduction. 2022 10 01; 164(4):R75-R86.

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Wang X, Wang W, Wang X, Wang M, Zhu L, Garba F, Fu C, Zieger B, Liu X, Liu X, Yao X. The septin complex links the catenin complex to the actin cytoskeleton for establishing epithelial cell polarity. J Mol Cell Biol. 2021 09 11; 13(6):395-408.

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Yao X. Modeling cellular polarity, plasticity, and disease disparity in 4D. J Mol Cell Biol. 2020 08 01; 12(8):559-561.

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Yang YH, Istomine R, Alvarez F, Al-Aubodah TA, Shi XQ, Takano T, Thornton AM, Shevach EM, Zhang J, Piccirillo CA. Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp3+ Regulatory T Cells. Cell Rep. 2020 02 04; 30(5):1515-1529.e4.

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Rivera-Robles MJ, Medina-Vel?zquez J, Asencio-Torres GM, Gonz?lez-Crespo S, Rymond BC, Rodr?guez-Medina J, Dharmawardhane S. Targeting Cdc42 with the anticancer compound MBQ-167 inhibits cell polarity and growth in the budding yeast S. cerevisiae. Small GTPases. 2020 11; 11(6):430-440.

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Manda B, Mir H, Gangwar R, Meena AS, Amin S, Shukla PK, Dalal K, Suzuki T, Rao R. Phosphorylation hotspot in the C-terminal domain of occludin regulates the dynamics of epithelial junctional complexes. J Cell Sci. 2018 04 06; 131(7).

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Polgar N, Fogelgren B. Regulation of Cell Polarity by Exocyst-Mediated Trafficking. Cold Spring Harb Perspect Biol. 2018 03 01; 10(3).

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Trivedi NH, Yu JJ, Hung CY, Doelger RP, Navara CS, Armitige LY, Seshu J, Sinai AP, Chambers JP, Guentzel MN, Arulanandam BP. Microbial co-infection alters macrophage polarization, phagosomal escape, and microbial killing. Innate Immun. 2018 04; 24(3):152-162.

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