Mucin-1

"Mucin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

Descriptor ID	D018396
MeSH Number(s)	D12.776.395.550.560 D12.776.395.560.631.115 D12.776.543.550.530 D23.050.285.050.300 D23.050.550.325.300 D23.101.140.075.300
Concept/Terms	Mucin-1 Mucin-1 Mucin 1 CA 15.3 Antigen Antigen, CA 15.3 Antigen CA-15-3 Antigen CA 15 3 CA-15-3, Antigen CA-15-3 Antigen Antigen, CA-15-3 Episialin CD227 Antigen Antigen, CD227 Polymorphic Epithelial Mucin Epithelial Membrane Antigen Antigen, Epithelial Membrane Membrane Antigen, Epithelial Muc1 Mucin Mucin, Muc1 Antigens, CD227 CD227 Antigens CA 15-3 Antigen Antigen, CA 15-3 CA 15 3 Antigen Epithelial Mucin, Polymorphic Mucin, Polymorphic Epithelial

Below are MeSH descriptors whose meaning is more general than "Mucin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Mucin-1 [D12.776.395.550.560]
Mucoproteins [D12.776.395.560]
Mucins [D12.776.395.560.631]
Mucin-1 [D12.776.395.560.631.115]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Mucin-1 [D12.776.543.550.530]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Neoplasm [D23.050.285]
Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]
Mucin-1 [D23.050.285.050.300]
Epitopes [D23.050.550]
Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]
Mucin-1 [D23.050.550.325.300]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]
Mucin-1 [D23.101.140.075.300]

Below are MeSH descriptors whose meaning is related to "Mucin-1".

Below are MeSH descriptors whose meaning is more specific than "Mucin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mucin-1" by people in this website by year, and whether "Mucin-1" was a major or minor topic of these publications.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	0	1
2004	0	1	1
2006	0	2	2
2007	0	1	1
2012	1	0	1
2018	1	0	1
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "Mucin-1" by people in Profiles.

Mehta A, Azam S, Rahmani A, Rizvi M, Mandal A. Expression of epithelial membrane antigen and cytokeratin among Indian workers exposed to cotton fibre dust in textile industries. East Mediterr Health J. 2022 Feb 27; 28(2):152-157.

View in: PubMed
Mohl JE, Gerken TA, Leung MY. ISOGlyP: de novo prediction of isoform-specific mucin-type O-glycosylation. Glycobiology. 2021 04 01; 31(3):168-172.

View in: PubMed
Rathinavelu A, Kanagasabai T, Dhandayuthapani S, Alhazzani K. Anti-angiogenic and pro-apoptotic effects of a small-molecule JFD-WS in in vitro and breast cancer xenograft mouse models. Oncol Rep. 2018 Apr; 39(4):1711-1724.

View in: PubMed
Raina D, Agarwal P, Lee J, Bharti A, McKnight CJ, Sharma P, Kharbanda S, Kufe D. Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target. PLoS One. 2015; 10(8):e0135156.

View in: PubMed
Song W, Delyria ES, Chen J, Huang W, Lee JS, Mittendorf EA, Ibrahim N, Radvanyi LG, Li Y, Lu H, Xu H, Shi Y, Wang LX, Ross JA, Rodrigues SP, Almeida IC, Yang X, Qu J, Schocker NS, Michael K, Zhou D. MUC1 glycopeptide epitopes predicted by computational glycomics. Int J Oncol. 2012 Dec; 41(6):1977-84.

View in: PubMed
Chauhan SC, Vinayek N, Maher DM, Bell MC, Dunham KA, Koch MD, Lio Y, Jaggi M. Combined staining of TAG-72, MUC1, and CA125 improves labeling sensitivity in ovarian cancer: antigens for multi-targeted antibody-guided therapy. J Histochem Cytochem. 2007 Aug; 55(8):867-75.

View in: PubMed
Chauhan SC, Singh AP, Ruiz F, Johansson SL, Jain M, Smith LM, Moniaux N, Batra SK. Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125). Mod Pathol. 2006 Oct; 19(10):1386-94.

View in: PubMed
Mitchell MS, Lund TA, Sewell AK, Marincola FM, Paul E, Schroder K, Wilson DB, Kan-Mitchell J. The cytotoxic T cell response to peptide analogs of the HLA-A*0201-restricted MUC1 signal sequence epitope, M1.2. Cancer Immunol Immunother. 2007 Mar; 56(3):287-301.

View in: PubMed
Singh AP, Chauhan SC, Bafna S, Johansson SL, Smith LM, Moniaux N, Lin MF, Batra SK. Aberrant expression of transmembrane mucins, MUC1 and MUC4, in human prostate carcinomas. Prostate. 2006 Mar 01; 66(4):421-9.

View in: PubMed
Wang H, Lillehoj EP, Kim KC. MUC1 tyrosine phosphorylation activates the extracellular signal-regulated kinase. Biochem Biophys Res Commun. 2004 Aug 20; 321(2):448-54.

View in: PubMed

People

Explore

Similar Concepts

Top Journals