"Protein Kinase C-delta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed protein kinase that is involved in a variety of cellular SIGNAL PATHWAYS. Its activity is regulated by a variety of signaling protein tyrosine kinase.
Descriptor ID |
D051745
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MeSH Number(s) |
D08.811.913.696.620.682.700.725.400
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Concept/Terms |
Protein Kinase C-delta- Protein Kinase C-delta
- Kinase C-delta, Protein
- Protein Kinase C delta
- PKC-delta Serine-Threonine Kinase
- PKC delta Serine Threonine Kinase
- Serine-Threonine Kinase, PKC-delta
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Below are MeSH descriptors whose meaning is more general than "Protein Kinase C-delta".
Below are MeSH descriptors whose meaning is more specific than "Protein Kinase C-delta".
This graph shows the total number of publications written about "Protein Kinase C-delta" by people in this website by year, and whether "Protein Kinase C-delta" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2002 | 0 | 3 | 3 |
2003 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2005 | 0 | 3 | 3 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2017 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Kinase C-delta" by people in Profiles.
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Shimoyama Y, Yamada K, Yoshida S, Kawamura A, Hannya Y, Imaizumi Y, Kumamoto T, Takeda Y, Shimoda M, Eto K, Yoshida K. Inhibition of protein kinase C delta leads to cellular senescence to induce anti-tumor effects in colorectal cancer. Cancer Sci. 2023 Jun; 114(6):2471-2484.
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Nu?ez RE, Javadov S, Escobales N. Angiotensin II-preconditioning is associated with increased PKCe/PKCd ratio and prosurvival kinases in mitochondria. Clin Exp Pharmacol Physiol. 2017 Dec; 44(12):1201-1212.
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Chen BR, Cheng HH, Lin WC, Wang KH, Liou JY, Chen PF, Wu KK. Quiescent fibroblasts are more active in mounting robust inflammatory responses than proliferative fibroblasts. PLoS One. 2012; 7(11):e49232.
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Sidoryk-Wegrzynowicz M, Lee E, Aschner M. Mechanism of Mn(II)-mediated dysregulation of glutamine-glutamate cycle: focus on glutamate turnover. J Neurochem. 2012 Aug; 122(4):856-67.
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Ndebele K, Gona P, Jin TG, Benhaga N, Chalah A, Degli-Esposti M, Khosravi-Far R. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induced mitochondrial pathway to apoptosis and caspase activation is potentiated by phospholipid scramblase-3. Apoptosis. 2008 Jul; 13(7):845-56.
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Schwegmann A, Guler R, Cutler AJ, Arendse B, Horsnell WG, Flemming A, Kottmann AH, Ryan G, Hide W, Leitges M, Seoighe C, Brombacher F. Protein kinase C delta is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes. Proc Natl Acad Sci U S A. 2007 Oct 09; 104(41):16251-6.
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Renault-Mihara F, Beuvon F, Iturrioz X, Canton B, De Bouard S, L?onard N, Mouhamad S, Sharif A, Ramos JW, Junier MP, Chneiweiss H. Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism. Mol Biol Cell. 2006 Dec; 17(12):5141-52.
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Sandra F, Degli Esposti M, Ndebele K, Gona P, Knight D, Rosenquist M, Khosravi-Far R. Tumor necrosis factor-related apoptosis-inducing ligand alters mitochondrial membrane lipids. Cancer Res. 2005 Sep 15; 65(18):8286-97.
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Woolfolk EA, Eguchi S, Ohtsu H, Nakashima H, Ueno H, Gerthoffer WT, Motley ED. Angiotensin II-induced activation of p21-activated kinase 1 requires Ca2+ and protein kinase C{delta} in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2005 Nov; 289(5):C1286-94.
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Jackson D, Zheng Y, Lyo D, Shen Y, Nakayama K, Nakayama KI, Humphries MJ, Reyland ME, Foster DA. Suppression of cell migration by protein kinase Cdelta. Oncogene. 2005 Apr 21; 24(18):3067-72.