Aptamers, Nucleotide

"Aptamers, Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.

Descriptor ID	D052157
MeSH Number(s)	D13.695.578.424.224
Concept/Terms	Aptamers, Nucleotide Aptamers, Nucleotide Nucleotide Aptamers RNA Aptamers RNA Aptamers Aptamers, RNA Oligonucleotide Ligands, RNA RNA Oligonucleotide Ligands DNA Aptamers DNA Aptamers Aptamers, DNA Oligonucleotide Ligands, DNA DNA Oligonucleotide Ligands

Below are MeSH descriptors whose meaning is more general than "Aptamers, Nucleotide".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Polynucleotides [D13.695.578]
Oligonucleotides [D13.695.578.424]
Aptamers, Nucleotide [D13.695.578.424.224]

Below are MeSH descriptors whose meaning is related to "Aptamers, Nucleotide".

Below are MeSH descriptors whose meaning is more specific than "Aptamers, Nucleotide".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Aptamers, Nucleotide" by people in this website by year, and whether "Aptamers, Nucleotide" was a major or minor topic of these publications.

Bar chart showing 45 publications over 20 distinct years, with a maximum of 4 publications in 2010 and 2021 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	0	1	1
2006	2	0	2
2008	2	1	3
2009	1	0	1
2010	3	1	4
2011	0	3	3
2012	1	1	2
2013	1	1	2
2014	2	0	2
2015	2	1	3
2016	3	0	3
2017	3	0	3
2018	2	0	2
2019	1	0	1
2020	0	2	2
2021	2	2	4
2022	1	0	1
2023	1	0	1
2024	3	1	4
2025	1	0	1

Below are the most recent publications written about "Aptamers, Nucleotide" by people in Profiles.

Egbe Vydaline AO, Rozhkov S, Sosa G, Mallikaratchy P. Aptamers as target-specific recognition elements in drug delivery. Adv Drug Deliv Rev. 2025 Nov; 226:115685.

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Ryan AK, Rahman S, Williams RM. Optical Aptamer-Based Cytokine Nanosensor Detects Macrophage Activation by Bacterial Toxins. ACS Sens. 2024 07 26; 9(7):3697-3706.

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Lim J, Son SU, Ki J, Kim S, Lee J, Jang S, Seo SB, Jang H, Kang T, Jung J, Kim E, Lim EK. Dual structure-switching aptamer-mediated signal amplification cascade for SARS-CoV-2 detection. Biosens Bioelectron. 2024 Sep 01; 259:116375.

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Wang B, Pan X, Teng IT, Li X, Kobeissy F, Wu ZY, Zhu J, Cai G, Yan H, Yan X, Liang M, Yu F, Lu J, Yang Z, Biondi E, Haskins W, Cao YC, Benner SA, Tan W, Wang KK. Functional Selection of Tau Oligomerization-Inhibiting Aptamers. Angew Chem Int Ed Engl. 2024 04 24; 63(18):e202402007.

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Wang B, Kobeissy F, Golpich M, Cai G, Li X, Abedi R, Haskins W, Tan W, Benner SA, Wang KKW. Aptamer Technologies in Neuroscience, Neuro-Diagnostics and Neuro-Medicine Development. Molecules. 2024 Mar 02; 29(5).

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Williams N, Patel R, Mallikaratchy P. Discovery of Aptamers Against Cell Surface Markers Using Ligand-Guided Selection. Methods Mol Biol. 2023; 2570:13-38.

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Williams NB, Batool S, Zumrut HE, Patel R, Sosa G, Jamal M, Mallikaratchy P. An In Vitro Selection Platform to Identify Multiple Aptamers against Multiple Cell-Surface Markers Using Ligand-Guided Selection. Biochemistry. 2022 08 02; 61(15):1600-1613.

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Heredia FL, Roche-Lima A, Par?s-Matos EI. A novel artificial intelligence-based approach for identification of deoxynucleotide aptamers. PLoS Comput Biol. 2021 08; 17(8):e1009247.

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Yan Y, Narayan A, Cho S, Cheng Z, Liu JO, Zhu H, Wang G, Wharram B, Lisok A, Brummet M, Saeki H, Huang T, Gabrielson K, Gabrielson E, Cope L, Kanaan YM, Afsari A, Naab T, Yfantis HG, Ambs S, Pomper MG, Sukumar S, Merino VF. CRY?B2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer. Oncogene. 2021 09; 40(38):5752-5763.

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Yang CH, Wu TH, Chang CC, Lo HY, Liu HW, Huang NT, Lin CW. Biosensing Amplification by Hybridization Chain Reaction on Phase-Sensitive Surface Plasmon Resonance. Biosensors (Basel). 2021 Mar 06; 11(3).

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