"Pyrimidine Dimers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dimers found in DNA chains damaged by ULTRAVIOLET RAYS. They consist of two adjacent PYRIMIDINE NUCLEOTIDES, usually THYMINE nucleotides, in which the pyrimidine residues are covalently joined by a cyclobutane ring. These dimers block DNA REPLICATION.
| Descriptor ID |
D011740
|
| MeSH Number(s) |
D03.383.742.686.600 D13.695.578.424.600 D13.695.740.600
|
| Concept/Terms |
Pyrimidine Dimers- Pyrimidine Dimers
- Dimers, Pyrimidine
- Cyclobutane-Pyrimidine Dimers
- Cyclobutane Pyrimidine Dimers
- Dimers, Cyclobutane-Pyrimidine
Thymine-Cyclobutane Dimer- Thymine-Cyclobutane Dimer
- Dimer, Thymine-Cyclobutane
- Thymine Cyclobutane Dimer
- Thymine-Thymine Cyclobutane Dimer
- Cyclobutane Dimer, Thymine-Thymine
- Dimer, Thymine-Thymine Cyclobutane
- Thymine Thymine Cyclobutane Dimer
- Thymine Dimers
- Dimers, Thymine
|
Below are MeSH descriptors whose meaning is more general than "Pyrimidine Dimers".
Below are MeSH descriptors whose meaning is more specific than "Pyrimidine Dimers".
This graph shows the total number of publications written about "Pyrimidine Dimers" by people in this website by year, and whether "Pyrimidine Dimers" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pyrimidine Dimers" by people in Profiles.
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Alhegaili AS, Ji Y, Sylvius N, Blades MJ, Karbaschi M, Tempest HG, Jones GDD, Cooke MS. Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes. Int J Mol Sci. 2019 Oct 15; 20(20).
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Kim G, Karbaschi M, Cooke M, Gaitas A. Light-based methods for whole blood bacterial inactivation enabled by a recirculating flow system. Photochem Photobiol. 2018 07; 94(4):744-751.
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Delinasios GJ, Karbaschi M, Cooke MS, Young AR. Vitamin E inhibits the UVAI induction of "light" and "dark" cyclobutane pyrimidine dimers, and oxidatively generated DNA damage, in keratinocytes. Sci Rep. 2018 01 11; 8(1):423.
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Cooke MS, Harry EL, Liljendahl TS, Segerb?ck D. DNA nucleotide excision repair, where do all the cyclobutane pyrimidine dimers go? Cell Cycle. 2013 May 15; 12(10):1642.
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Cooke MS, Robson A. Immunochemical detection of UV-induced DNA damage and repair. Methods Mol Biol. 2006; 314:215-28.
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Xu G, Spivak G, Mitchell DL, Mori T, McCarrey JR, McMahan CA, Walter RB, Hanawalt PC, Walter CA. Nucleotide excision repair activity varies among murine spermatogenic cell types. Biol Reprod. 2005 Jul; 73(1):123-30.
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Cooke MS, Podmore ID, Mistry N, Evans MD, Herbert KE, Griffiths HR, Lunec J. Immunochemical detection of UV-induced DNA damage and repair. J Immunol Methods. 2003 Sep; 280(1-2):125-33.
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Karakoula A, Evans MD, Podmore ID, Hutchinson PE, Lunec J, Cooke MS. Quantification of UVR-induced DNA damage: global- versus gene-specific levels of thymine dimers. J Immunol Methods. 2003 Jun 01; 277(1-2):27-37.
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Evans MD, Butler JM, Nicoll K, Cooke MS, Lunec J. 17 beta-Oestradiol attenuates nucleotide excision repair. FEBS Lett. 2003 Jan 30; 535(1-3):153-8.
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Cooke MS, Mistry N, Ahmad J, Waller H, Langford L, Bevan RJ, Evans MD, Jones GD, Herbert KE, Griffiths HR, Lunec J. Deoxycytidine glyoxal: lesion induction and evidence of repair following vitamin C supplementation in vivo. Free Radic Biol Med. 2003 Jan 15; 34(2):218-25.