A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.

Descriptor ID	D001057
MeSH Number(s)	D10.532.091.500 D12.776.070.400.500 D12.776.521.120.500
Concept/Terms	Apolipoproteins E Apolipoproteins E ApoE Apo E Apo-E Apolipoprotein E Isoproteins Apolipoprotein E Isoproteins Isoproteins, Apolipoprotein E Apo E Isoproteins Isoproteins, Apo E Apoproteins E Apoproteins E Apoprotein (E)

Below are MeSH descriptors whose meaning is more general than "Apolipoproteins E".

Below are MeSH descriptors whose meaning is related to "Apolipoproteins E".

Below are MeSH descriptors whose meaning is more specific than "Apolipoproteins E".