"SELEX Aptamer Technique" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A method of generating a large library of randomized nucleotides and selecting NUCLEOTIDE APTAMERS by iterative rounds of in vitro selection. A modified procedure substitutes AMINO ACIDS in place of NUCLEOTIDES to make PEPTIDE APTAMERS.
| Descriptor ID |
D052156
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| MeSH Number(s) |
E05.197.312.500 J01.897.836.249.249.500
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| Concept/Terms |
SELEX Aptamer Technique- SELEX Aptamer Technique
- Aptamer Technique, SELEX
- Aptamer Techniques, SELEX
- SELEX Aptamer Techniques
- Technique, SELEX Aptamer
- Techniques, SELEX Aptamer
- Systematic Evolution of Ligands by Exponential Enrichment
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Below are MeSH descriptors whose meaning is more general than "SELEX Aptamer Technique".
Below are MeSH descriptors whose meaning is more specific than "SELEX Aptamer Technique".
This graph shows the total number of publications written about "SELEX Aptamer Technique" by people in this website by year, and whether "SELEX Aptamer Technique" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2008 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "SELEX Aptamer Technique" by people in Profiles.
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Wang B, Kobeissy F, Golpich M, Cai G, Li X, Abedi R, Haskins W, Tan W, Benner SA, Wang KKW. Aptamer Technologies in Neuroscience, Neuro-Diagnostics and Neuro-Medicine Development. Molecules. 2024 Mar 02; 29(5).
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Williams N, Patel R, Mallikaratchy P. Discovery of Aptamers Against Cell Surface Markers Using Ligand-Guided Selection. Methods Mol Biol. 2023; 2570:13-38.
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Williams NB, Batool S, Zumrut HE, Patel R, Sosa G, Jamal M, Mallikaratchy P. An In Vitro Selection Platform to Identify Multiple Aptamers against Multiple Cell-Surface Markers Using Ligand-Guided Selection. Biochemistry. 2022 08 02; 61(15):1600-1613.
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Heredia FL, Roche-Lima A, Par?s-Matos EI. A novel artificial intelligence-based approach for identification of deoxynucleotide aptamers. PLoS Comput Biol. 2021 08; 17(8):e1009247.
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Zumrut H, Yang Z, Williams N, Arizala J, Batool S, Benner SA, Mallikaratchy P. Ligand-Guided Selection with Artificially Expanded Genetic Information Systems against TCR-CD3e. Biochemistry. 2020 02 04; 59(4):552-562.
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Batool S, Argyropoulos KV, Azad R, Okeoma P, Zumrut H, Bhandari S, Dekhang R, Mallikaratchy PR. Dimerization of an aptamer generated from Ligand-guided selection (LIGS) yields a high affinity scaffold against B-cells. Biochim Biophys Acta Gen Subj. 2019 01; 1863(1):232-240.
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Z?mr?t HE, Batool S, Van N, George S, Bhandari S, Mallikaratchy P. Structural optimization of an aptamer generated from Ligand-Guided Selection (LIGS) resulted in high affinity variant toward mIgM expressed on Burkitt's lymphoma cell lines. Biochim Biophys Acta Gen Subj. 2017 Jul; 1861(7):1825-1832.
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Mallikaratchy P. Evolution of Complex Target SELEX to Identify Aptamers against Mammalian Cell-Surface Antigens. Molecules. 2017 Jan 30; 22(2).
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Zumrut HE, Ara MN, Maio GE, Van NA, Batool S, Mallikaratchy PR. Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells. Anal Biochem. 2016 11 01; 512:1-7.
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Zumrut HE, Ara MN, Fraile M, Maio G, Mallikaratchy P. Ligand-Guided Selection of Target-Specific Aptamers: A Screening Technology for Identifying Specific Aptamers Against Cell-Surface Proteins. Nucleic Acid Ther. 2016 06; 26(3):190-8.