Receptors, Antigen, T-Cell

"Receptors, Antigen, T-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Molecules on the surface of T-lymphocytes that recognize and combine with antigens. The receptors are non-covalently associated with a complex of several polypeptides collectively called CD3 antigens (CD3 COMPLEX). Recognition of foreign antigen and the major histocompatibility complex is accomplished by a single heterodimeric antigen-receptor structure, composed of either alpha-beta (RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA) or gamma-delta (RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA) chains.

Descriptor ID	D011948
MeSH Number(s)	D12.776.543.750.705.816.824
Concept/Terms	Receptors, Antigen, T-Cell Receptors, Antigen, T-Cell T-Cell Antigen Receptor Antigen Receptor, T-Cell Receptor, T-Cell Antigen T Cell Antigen Receptor T-Cell Receptors Receptors, T-Cell T Cell Receptors T-Cell Receptor Receptor, T-Cell T Cell Receptor Receptors, T-Cell Antigen Receptors, T Cell Antigen T-Cell Antigen Receptors Antigen Receptors, T-Cell Antigen Receptors, T Cell

Below are MeSH descriptors whose meaning is more general than "Receptors, Antigen, T-Cell".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Antigen [D12.776.543.750.705.816]
Receptors, Antigen, T-Cell [D12.776.543.750.705.816.824]

Below are MeSH descriptors whose meaning is related to "Receptors, Antigen, T-Cell".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Antigen, T-Cell".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Antigen, T-Cell" by people in this website by year, and whether "Receptors, Antigen, T-Cell" was a major or minor topic of these publications.

Bar chart showing 55 publications over 26 distinct years, with a maximum of 4 publications in 2010 and 2016 and 2019 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2000	1	0	1
2001	1	1	2
2002	1	1	2
2003	0	1	1
2004	2	1	3
2005	0	2	2
2007	1	2	3
2009	1	0	1
2010	3	1	4
2011	0	2	2
2013	1	0	1
2014	1	0	1
2015	2	1	3
2016	2	2	4
2017	2	0	2
2018	0	1	1
2019	4	0	4
2020	1	1	2
2021	1	1	2
2022	0	2	2
2023	1	1	2
2024	1	3	4
2025	3	0	3
2026	1	0	1

Below are the most recent publications written about "Receptors, Antigen, T-Cell" by people in Profiles.

Sharma G, Teng F, Round J, Sneddon SA, Sivasothy S, Brown SD, Holt RA. Comprehensive self-antigen screening to assess cross-reactivity in promiscuous T-cell receptors. Front Immunol. 2025; 16:1719827.

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Xiong Z, Kong Q, Chagantipati B, Stepniak A, Jaswal AP, Sneiderman CT, Han Y, Jackson SA, Raphael RA, Zhang W, Li M, Chao Y, Qin B, Dulkadir Z, Schwegman L, Zhang Y, Kuminkoski C, Mahlke MA, Nath P, Hu B, Zinn PO, Mantica M, Agnihotri S, Nechemia-Arbely Y, Pollack IF, Rigatti LH, Forsthuber TG, Li X, Raphael I, Kohanbash G. C/EBP?-induced alternative splicing of RCAN1 generates a potent TCR-T target in mesenchymal glioblastoma. Cell Mol Immunol. 2026 Jan; 23(1):94-113.

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Landry LG, Wells KL, Anderson AM, Miller KR, Jones KL, Michels AW, Nakayama M. Quantitative V gene-targeted T cell receptor sequencing as a biomarker in type 1 diabetes. JCI Insight. 2026 Feb 09; 11(3).

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Raphael I, Xiong Z, Sneiderman CT, Raphael RA, Mash M, Schwegman L, Jackson SA, O'Brien C, Anderson KJ, Sever RE, Hendrikse LD, Vincze SR, Diaz A, Felker J, Nazarian J, Nechemia-Arbely Y, Hu B, Kammula US, Agnihotri S, Rich JN, Broniscer A, Drappatz J, Abel TJ, Uttam S, Hwang EI, Pearce TM, Taylor MD, Nisnboym M, Forsthuber TG, Pollack IF, Chikina M, Rajasundaram D, Kohanbash G. The T cell receptor landscape of childhood brain tumors. Sci Transl Med. 2025 Mar 19; 17(790):eadp0675.

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Ham H, Jing H, Lamborn IT, Kober MM, Koval A, Berchiche YA, Anderson DE, Druey KM, Mandl JN, Isidor B, Ferreira CR, Freeman AF, Ganesan S, Karsak M, Mustillo PJ, Teo J, Zolkipli-Cunningham Z, Chatron N, Lecoquierre F, Oler AJ, Schmid JP, Kuhns DB, Xu X, Hauck F, Al-Herz W, Wagner M, Terhal PA, Muurinen M, Barlogis V, Cruz P, Danielson J, Stewart H, Loid P, Rading S, Keren B, Pfundt R, Zarember KA, Vill K, Potocki L, Olivier KN, Lesca G, Faivre L, Wong M, Puel A, Chou J, Tusseau M, Moutsopoulos NM, Matthews HF, Simons C, Taft RJ, Soldatos A, Masle-Farquhar E, Pittaluga S, Brink R, Fink DL, Kong HH, Kabat J, Kim WS, Bierhals T, Meguro K, Hsu AP, Gu J, Stoddard J, Banos-Pinero B, Slack M, Trivellin G, Mazel B, Soomann M, Li S, Watts VJ, Stratakis CA, Rodriguez-Quevedo MF, Bruel AL, Lipsanen-Nyman M, Saultier P, Jain R, Lehalle D, Torres D, Sullivan KE, Barbarot S, Neu A, Duffourd Y, Similuk M, McWalter K, Blanc P, B?zieau S, Jin T, Geha RS, Casanova JL, Makitie OM, Kubisch C, Edery P, Christodoulou J, Germain RN, Goodnow CC, Sakmar TP, Billadeau DD, K?ry S, Katanaev VL, Zhang Y, Lenardo MJ, Su HC. Germline mutations in a G protein identify signaling cross-talk in T cells. Science. 2024 09 20; 385(6715):eadd8947.

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Short L, Holt RA, Cullis PR, Evgin L. Direct in vivo CAR T cell engineering. Trends Pharmacol Sci. 2024 05; 45(5):406-418.

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Fasoulis R, Rigo MM, Liz?e G, Antunes DA, Kavraki LE. APE-Gen2.0: Expanding Rapid Class I Peptide-Major Histocompatibility Complex Modeling to Post-Translational Modifications and Noncanonical Peptide Geometries. J Chem Inf Model. 2024 03 11; 64(5):1730-1750.

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Perez C, Plaza-Rojas L, Boucher JC, Nagy MZ, Kostenko E, Prajapati K, Burke B, Reyes MD, Austin AL, Zhang S, Le PT, Guevara-Patino JA. NKG2D receptor signaling shapes T cell thymic education. J Leukoc Biol. 2024 01 19; 115(2):306-321.

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Fonseca AF, Antunes DA. CrossDome: an interactive R package to predict cross-reactivity risk using immunopeptidomics databases. Front Immunol. 2023; 14:1142573.

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Williams N, Patel R, Mallikaratchy P. Discovery of Aptamers Against Cell Surface Markers Using Ligand-Guided Selection. Methods Mol Biol. 2023; 2570:13-38.

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