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Prabodhika Mallikaratchy, PhD

TitleMEDICAL PROFESSOR
Faculty RankProfessor
InstitutionCity University of New York
DepartmentMolecular Cellular and Biomedical Sciences
Address160 Convent Ave
New York NY 10031
Phone+12126505896
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Egbe Vydaline AO, Rozhkov S, Sosa G, Mallikaratchy P. Aptamers as target-specific recognition elements in drug delivery. Adv Drug Deliv Rev. 2025 Nov; 226:115685. PMID: 40925520.
      Citations:    Fields:    
    2. Williams N, Patel R, Mallikaratchy P. Discovery of Aptamers Against Cell Surface Markers Using Ligand-Guided Selection. Methods Mol Biol. 2023; 2570:13-38. PMID: 36156771.
      Citations: 1     Fields:    Translation:Humans
    3. Williams NB, Batool S, Zumrut HE, Patel R, Sosa G, Jamal M, Mallikaratchy P. An In Vitro Selection Platform to Identify Multiple Aptamers against Multiple Cell-Surface Markers Using Ligand-Guided Selection. Biochemistry. 2022 08 02; 61(15):1600-1613. PMID: 35829681.
      Citations: 2     Fields:    Translation:Humans
    4. Boykoff N, Freage L, Lenn J, Mallikaratchy P. Bispecific Aptamer Sensor toward T-Cell Leukemia Detection in the Tumor Microenvironment. ACS Omega. 2021 Dec 07; 6(48):32563-32570. PMID: 34901605.
      Citations:    
    5. Freage L, Boykoff N, Mallikaratchy P. Utility of Multivalent Aptamers to Develop Nanoscale DNA Devices against Surface Receptors. ACS Omega. 2021 May 18; 6(19):12382-12391. PMID: 34056390.
      Citations:    
    6. Freage L, Jamal D, Williams NB, Mallikaratchy PR. A Homodimeric Aptamer Variant Generated from Ligand-Guided Selection Activates the T Cell Receptor Cluster of Differentiation 3 Complex. Mol Ther Nucleic Acids. 2020 Aug 19; 22:167-178. PMID: 32920262.
      Citations:    
    7. Zumrut H, Yang Z, Williams N, Arizala J, Batool S, Benner SA, Mallikaratchy P. Ligand-Guided Selection with Artificially Expanded Genetic Information Systems against TCR-CD3e. Biochemistry. 2020 02 04; 59(4):552-562. PMID: 31880917.
      Citations: 11     Fields:    Translation:HumansCells
    8. Zumrut HE, Mallikaratchy PR. Ligand Guided Selection (LIGS) of Artificial Nucleic Acid Ligands against Cell Surface Targets. ACS Appl Bio Mater. 2020 May 18; 3:2545-2552. PMID: 34013167.
      Citations: 7     Fields:    
    9. Zumrut HE, Batool S, Argyropoulos KV, Williams N, Azad R, Mallikaratchy PR. Integrating Ligand-Receptor Interactions and In?Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands. Mol Ther Nucleic Acids. 2019 Sep 06; 17:150-163. PMID: 31255977.
      Citations:    
    10. Moccia F, Platella C, Musumeci D, Batool S, Zumrut H, Bradshaw J, Mallikaratchy P, Montesarchio D. The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition. Int J Biol Macromol. 2019 Jul 15; 133:839-849. PMID: 31022491.
      Citations: 14     Fields:    Translation:HumansCells
    11. Lingala S, Nordstr?m LU, Mallikaratchy PR. Synthesis of stable azide and alkyne functionalized phosphoramidite nucleosides. Tetrahedron Lett. 2019 Jan 17; 60(3):211-213. PMID: 30804607.
      Citations: 4     Fields:    
    12. Batool S, Argyropoulos KV, Azad R, Okeoma P, Zumrut H, Bhandari S, Dekhang R, Mallikaratchy PR. Dimerization of an aptamer generated from Ligand-guided selection (LIGS) yields a high affinity scaffold against B-cells. Biochim Biophys Acta Gen Subj. 2019 01; 1863(1):232-240. PMID: 30342154.
      Citations: 15     Fields:    Translation:HumansCells
    13. Batool S, Bhandari S, George S, Okeoma P, Van N, Z?mr?t HE, Mallikaratchy P. Engineered Aptamers to Probe Molecular Interactions on the Cell Surface. Biomedicines. 2017 Aug 29; 5(3). PMID: 28850067.
      Citations:    
    14. Z?mr?t HE, Batool S, Van N, George S, Bhandari S, Mallikaratchy P. Structural optimization of an aptamer generated from Ligand-Guided Selection (LIGS) resulted in high affinity variant toward mIgM expressed on Burkitt's lymphoma cell lines. Biochim Biophys Acta Gen Subj. 2017 Jul; 1861(7):1825-1832. PMID: 28363693.
      Citations: 15     Fields:    Translation:HumansCells
    15. Maio G, Enweronye O, Zumrut HE, Batool S, Van N, Mallikaratchy P. Systematic optimization and modification of a DNA aptamer with 2'-O-methyl RNA analogues. ChemistrySelect. 2017 Mar 01; 2(7):2335-2340. PMID: 29226219.
      Citations:    
    16. Mallikaratchy P. Evolution of Complex Target SELEX to Identify Aptamers against Mammalian Cell-Surface Antigens. Molecules. 2017 Jan 30; 22(2). PMID: 28146093.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    17. Zumrut HE, Ara MN, Maio GE, Van NA, Batool S, Mallikaratchy PR. Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells. Anal Biochem. 2016 11 01; 512:1-7. PMID: 27519622.
      Citations: 17     Fields:    Translation:HumansCells
    18. Zumrut HE, Ara MN, Fraile M, Maio G, Mallikaratchy P. Ligand-Guided Selection of Target-Specific Aptamers: A Screening Technology for Identifying Specific Aptamers Against Cell-Surface Proteins. Nucleic Acid Ther. 2016 06; 26(3):190-8. PMID: 27148897.
      Citations: 30     Fields:    Translation:HumansCells
    19. Mallikaratchy P, Gardner J, Nordstr?m LU, Veomett NJ, McDevitt MR, Heaney ML, Scheinberg DA. A self-assembling short oligonucleotide duplex suitable for pretargeting. Nucleic Acid Ther. 2013 Aug; 23(4):289-99. PMID: 23848521.
      Citations: 8     Fields:    Translation:AnimalsCells
    20. Mallikaratchy PR, Ruggiero A, Gardner JR, Kuryavyi V, Maguire WF, Heaney ML, McDevitt MR, Patel DJ, Scheinberg DA. A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia. Nucleic Acids Res. 2011 Mar; 39(6):2458-69. PMID: 21030439.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    21. Tang Z, Zhu Z, Mallikaratchy P, Yang R, Sefah K, Tan W. Aptamer-target binding triggered molecular mediation of singlet oxygen generation. Chem Asian J. 2010 Apr 01; 5(4):783-6. PMID: 20340154.
      Citations: 6     Fields:    Translation:HumansCells
    22. Mallikaratchy P, Liu H, Huang YF, Wang H, Lopez-Colon D, Tan W. Using aptamers evolved from cell-SELEX to engineer a molecular delivery platform. Chem Commun (Camb). 2009 Jun 07; (21):3056-8. PMID: 19462085.
      Citations: 6     Fields:    Translation:HumansCells
    23. Tang Z, Mallikaratchy P, Yang R, Kim Y, Zhu Z, Wang H, Tan W. Aptamer switch probe based on intramolecular displacement. J Am Chem Soc. 2008 Aug 27; 130(34):11268-9. PMID: 18680291.
      Citations: 58     Fields:    Translation:HumansCells
    24. Shangguan D, Cao Z, Meng L, Mallikaratchy P, Sefah K, Wang H, Li Y, Tan W. Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J Proteome Res. 2008 May; 7(5):2133-9. PMID: 18363322.
      Citations: 177     Fields:    Translation:HumansCells
    25. Mallikaratchy P, Tang Z, Tan W. Cell specific aptamer-photosensitizer conjugates as a molecular tool in photodynamic therapy. ChemMedChem. 2008 Mar; 3(3):425-8. PMID: 18058891.
      Citations: 27     Fields:    Translation:HumansCells
    26. Mallikaratchy P, Tang Z, Kwame S, Meng L, Shangguan D, Tan W. Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in Burkitt's lymphoma cells. Mol Cell Proteomics. 2007 Dec; 6(12):2230-8. PMID: 17875608.
      Citations: 106     Fields:    Translation:HumansCells
    27. Shangguan D, Li Y, Tang Z, Cao ZC, Chen HW, Mallikaratchy P, Sefah K, Yang CJ, Tan W. Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):11838-43. PMID: 16873550.
      Citations: 469     Fields:    Translation:HumansCells
    28. Mallikaratchy P, Stahelin RV, Cao Z, Cho W, Tan W. Selection of DNA ligands for protein kinase C-delta. Chem Commun (Camb). 2006 Aug 14; (30):3229-31. PMID: 17028752.
      Citations: 27     Fields:    Translation:Cells
    29. Mallikaratchy P, Norman RE, Fronczek FR, Junk T. Tribromo(3,5-dimethyl-2-nitrophenyl-kappa(2)C(1),O)tellurium(IV), bromo(3,5-dimethyl-2-nitrophenyl-kappa(2)C(1),O)tellurium(II) and bromo(3,5-dimethyl-2-nitrosophenyl-kappa(2)C(1),O)tellurium(II). Acta Crystallogr C. 2003 Oct; 59(Pt 10):O571-4. PMID: 14532674.
      Citations: 1     Fields:    
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