Toll-Like Receptors

"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.

Descriptor ID	D051193
MeSH Number(s)	D12.776.543.750.705.910.500
Concept/Terms	Toll-Like Receptors Toll-Like Receptors Toll Like Receptors Toll-Like Receptor Receptor, Toll-Like Toll Like Receptor Receptors, Toll-Like Receptors, Toll Like

Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Pattern Recognition [D12.776.543.750.705.910]
Toll-Like Receptors [D12.776.543.750.705.910.500]

Below are MeSH descriptors whose meaning is related to "Toll-Like Receptors".

Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.

Bar chart showing 48 publications over 23 distinct years, with a maximum of 5 publications in 2002

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
1998	0	1	1
1999	0	1	1
2000	0	1	1
2002	0	5	5
2004	0	4	4
2005	1	2	3
2006	1	1	2
2008	1	1	2
2009	3	1	4
2010	1	1	2
2011	2	0	2
2012	1	0	1
2013	1	0	1
2014	2	1	3
2015	0	3	3
2016	0	2	2
2017	1	1	2
2018	0	1	1
2019	0	1	1
2020	3	1	4
2021	1	0	1

Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.

Banerjee S, Thompson WE, Chowdhury I. Emerging roles of microRNAs in the regulation of Toll-like receptor (TLR)-signaling. Front Biosci (Landmark Ed). 2021 01 01; 26(4):771-796.

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Eastman AJ, Vrana EN, Grimaldo MT, Jones AD, Rogers LM, Alcendor DJ, Aronoff DM. Cytotrophoblasts suppress macrophage-mediated inflammation through a contact-dependent mechanism. Am J Reprod Immunol. 2021 03; 85(3):e13352.

View in: PubMed
Dubey B, Jackson M, Zeigler-Johnson C, Devarajan K, Flores-Obando RE, McFarlane-Anderson N, Tulloch-Reid M, Aiken W, Kimbro K, Reed D, Kidd LR, Gibbs D, Kumar S, Ragin C. Interactive effect of TLR SNPs and exposure to sexually transmitted infections on prostate cancer risk in Jamaican men. Prostate. 2020 11; 80(15):1365-1372.

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Momtazmanesh S, Perry G, Rezaei N. Toll-like receptors in Alzheimer's disease. J Neuroimmunol. 2020 11 15; 348:577362.

View in: PubMed
Figueroa-Santiago O, Espino A. Possible Role for Toll-Like Receptors in Interaction of Fasciola hepatica Excretory-Secretory Products with Human Monocyte Cell Line. Methods Mol Biol. 2020; 2137:171-180.

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Ruffner MA, Song L, Maurer K, Shi L, Carroll MC, Wang JX, Muir AB, Spergel JM, Sullivan KE. Toll-like receptor 2 stimulation augments esophageal barrier integrity. Allergy. 2019 12; 74(12):2449-2460.

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Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G. Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine. Cell Death Differ. 2018 11; 25(11):1885-1904.

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Wu G, McBride DW, Zhang JH. Axl activation attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-?B pathway after MCAO in rats. Neurobiol Dis. 2018 02; 110:59-67.

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Capilla A, Karachentsev D, Patterson RA, Hermann A, Juarez MT, McGinnis W. Toll pathway is required for wound-induced expression of barrier repair genes in the Drosophila epidermis. Proc Natl Acad Sci U S A. 2017 03 28; 114(13):E2682-E2688.

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Sharma A, Sharma P, Vishwakarma AL, Srivastava M. Functional Impairment of Murine Dendritic Cell Subsets following Infection with Infective Larval Stage 3 of Brugia malayi. Infect Immun. 2017 Jan; 85(1).

View in: PubMed

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