Toll-Like Receptor 2

"Toll-Like Receptor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pattern recognition receptor that forms heterodimers with other TOLL-LIKE RECEPTORS. It interacts with multiple ligands including PEPTIDOGLYCAN, bacterial LIPOPROTEINS, lipoarabinomannan, and a variety of PORINS.

Descriptor ID	D051195
MeSH Number(s)	D12.776.543.750.705.910.500.200
Concept/Terms	Toll-Like Receptor 2 Toll-Like Receptor 2 Toll Like Receptor 2 TLR2 Receptor Receptor, TLR2

Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 2".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Pattern Recognition [D12.776.543.750.705.910]
Toll-Like Receptors [D12.776.543.750.705.910.500]
Toll-Like Receptor 2 [D12.776.543.750.705.910.500.200]

Below are MeSH descriptors whose meaning is related to "Toll-Like Receptor 2".

Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 2".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Toll-Like Receptor 2" by people in this website by year, and whether "Toll-Like Receptor 2" was a major or minor topic of these publications.

Bar chart showing 22 publications over 11 distinct years, with a maximum of 4 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2004	0	2	2
2006	1	0	1
2009	2	0	2
2010	1	1	2
2011	1	1	2
2012	3	1	4
2013	2	0	2
2014	3	0	3
2019	1	0	1
2020	1	1	2

Below are the most recent publications written about "Toll-Like Receptor 2" by people in Profiles.

Cronemberger-Andrade A, Xander P, Soares RP, Pessoa NL, Campos MA, Ellis CC, Grajeda B, Ofir-Birin Y, Almeida IC, Regev-Rudzki N, Torrecilhas AC. Trypanosoma cruzi-Infected Human Macrophages Shed Proinflammatory Extracellular Vesicles That Enhance Host-Cell Invasion via Toll-Like Receptor 2. Front Cell Infect Microbiol. 2020; 10:99.

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Chu J, Li X, Qu G, Wang Y, Li Q, Guo Y, Hou L, Liu J, Eko FO, He C. Chlamydia psittaci PmpD-N Exacerbated Chicken Macrophage Function by Triggering Th2 Polarization and the TLR2/MyD88/NF-?B Signaling Pathway. Int J Mol Sci. 2020 Mar 15; 21(6).

View in: PubMed
Ruffner MA, Song L, Maurer K, Shi L, Carroll MC, Wang JX, Muir AB, Spergel JM, Sullivan KE. Toll-like receptor 2 stimulation augments esophageal barrier integrity. Allergy. 2019 12; 74(12):2449-2460.

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Kaiser R, Tang LF, Taylor KE, Sterba K, Nititham J, Brown EE, Edberg JC, McGwin G, Alarc?n GS, Ramsey-Goldman R, Reveille JD, Vil? LM, Petri M, Rauch J, Miller E, Mesznik K, Kwok PY, Kimberly RP, Salmon JE, Criswell LA. A polymorphism in TLR2 is associated with arterial thrombosis in a multiethnic population of patients with systemic lupus erythematosus. Arthritis Rheumatol. 2014 Jul; 66(7):1882-7.

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Mariano VS, Zorzetto-Fernandes AL, da Silva TA, Ruas LP, Nohara LL, Almeida IC, Roque-Barreira MC. Recognition of TLR2 N-glycans: critical role in ArtinM immunomodulatory activity. PLoS One. 2014; 9(6):e98512.

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Hung CY, Jim?nez-Alzate Mdel P, Gonzalez A, W?thrich M, Klein BS, Cole GT. Interleukin-1 receptor but not Toll-like receptor 2 is essential for MyD88-dependent Th17 immunity to Coccidioides infection. Infect Immun. 2014 May; 82(5):2106-14.

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Carneiro AB, Iaciura BM, Nohara LL, Lopes CD, Veas EM, Mariano VS, Bozza PT, Lopes UG, Atella GC, Almeida IC, Silva-Neto MA. Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-?B translocation and MAPK/ERK phosphorylation. PLoS One. 2013; 8(9):e76233.

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Rogers EN, Jones DZ, Kidd NC, Yeyeodu S, Brock G, Ragin C, Jackson M, McFarlane-Anderson N, Tulloch-Reid M, Sean Kimbro K, Kidd LR. Toll-like receptor-associated sequence variants and prostate cancer risk among men of African descent. Genes Immun. 2013 Sep; 14(6):347-55.

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Lee GL, Chang YW, Wu JY, Wu ML, Wu KK, Yet SF, Kuo CC. TLR 2 induces vascular smooth muscle cell migration through cAMP response element-binding protein-mediated interleukin-6 production. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2751-60.

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Brinkworth JF, Pechenkina EA, Silver J, Goyert SM. Innate immune responses to TLR2 and TLR4 agonists differ between baboons, chimpanzees and humans. J Med Primatol. 2012 Dec; 41(6):388-93.

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