"E-Box Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
| Descriptor ID |
D024721
|
| MeSH Number(s) |
G02.111.570.080.689.330.240 G05.360.080.689.330.240 G05.360.340.024.340.137.750.249.240
|
| Concept/Terms |
E-Box Elements- E-Box Elements
- E Box Elements
- E-Box Element
- Element, E-Box
- Elements, E-Box
- E-Box Sequences
- E Box Sequences
- E-Box Sequence
- Sequence, E-Box
- Sequences, E-Box
- E-Box Sites
- E Box Sites
- E-Box Site
- Site, E-Box
- Sites, E-Box
- E-Box Motifs
- E Box Motifs
- E-Box Motif
- Motif, E-Box
- Motifs, E-Box
|
Below are MeSH descriptors whose meaning is more general than "E-Box Elements".
Below are MeSH descriptors whose meaning is more specific than "E-Box Elements".
This graph shows the total number of publications written about "E-Box Elements" by people in this website by year, and whether "E-Box Elements" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "E-Box Elements" by people in Profiles.
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Jiang S, Galindo MR, Jarrett HW. Purification and identification of a transcription factor, USF-2, binding to E-box element in the promoter of human telomerase reverse transcriptase (hTERT). Proteomics. 2010 Jan; 10(2):203-11.
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Bertolucci C, Cavallari N, Colognesi I, Aguzzi J, Chen Z, Caruso P, Fo? A, Tosini G, Bernardi F, Pinotti M. Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators. Mol Cell Biol. 2008 May; 28(9):3070-5.