"Pentamidine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
| Descriptor ID |
D010419
|
| MeSH Number(s) |
D02.078.100.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pentamidine".
Below are MeSH descriptors whose meaning is more specific than "Pentamidine".
This graph shows the total number of publications written about "Pentamidine" by people in this website by year, and whether "Pentamidine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Pentamidine" by people in Profiles.
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Al-Horani RA, Clemons D, Mottamal M. The In Vitro Effects of Pentamidine Isethionate on Coagulation and Fibrinolysis. Molecules. 2019 Jun 06; 24(11).
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Berger ML, Maciejewska D, Vanden Eynde JJ, Mottamal M, Zabinski J, Kazmierczak P, Rezler M, Jarak I, Piantanida I, Karminski-Zamola G, Mayence A, Rebernik P, Kumar A, Ismail MA, Boykin DW, Huang TL. Pentamidine analogs as inhibitors of [(3)H]MK-801 and [(3)H]ifenprodil binding to rat brain NMDA receptors. Bioorg Med Chem. 2015 Aug 01; 23(15):4489-4500.
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Chen X, Qiu L, Li M, D?rrnagel S, Orser BA, Xiong ZG, MacDonald JF. Diarylamidines: high potency inhibitors of acid-sensing ion channels. Neuropharmacology. 2010 Jun; 58(7):1045-53.
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Graves RA, Pamujula S, Moiseyev R, Freeman T, Bostanian LA, Mandal TK. Effect of different ratios of high and low molecular weight PLGA blend on the characteristics of pentamidine microcapsules. Int J Pharm. 2004 Feb 11; 270(1-2):251-62.
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Mandal TK, Bostanian LA, Graves RA, Chapman SR, Idodo TU. Porous biodegradable microparticles for delivery of pentamidine. Eur J Pharm Biopharm. 2001 Jul; 52(1):91-6.
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Mandal TK. Effect of solvent on the characteristics of pentamidine loaded microcapsule. J Biomater Sci Polym Ed. 1999; 10(1):1-17.
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Mandal TK. Evaluation of a novel phase separation technique for the encapsulation of water-soluble drugs in biodegradable polymer. Drug Dev Ind Pharm. 1998 Jul; 24(7):623-9.