"Werner Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal recessive disorder that causes premature aging in adults, characterized by sclerodermal skin changes, cataracts, subcutaneous calcification, muscular atrophy, a tendency to diabetes mellitus, aged appearance of the face, baldness, and a high incidence of neoplastic disease.
| Descriptor ID |
D014898
|
| MeSH Number(s) |
C16.320.925 C18.452.284.960
|
| Concept/Terms |
Werner Syndrome- Werner Syndrome
- Syndrome, Werner
- Adult Progeria
- Werner's Syndrome
- Syndrome, Werner's
- Werners Syndrome
- Syndrome, Werners
- Adult Premature Aging Syndrome
- Progeria, Adult
|
Below are MeSH descriptors whose meaning is more general than "Werner Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Werner Syndrome".
This graph shows the total number of publications written about "Werner Syndrome" by people in this website by year, and whether "Werner Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Werner Syndrome" by people in Profiles.
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Sommers JA, Sharma S, Doherty KM, Karmakar P, Yang Q, Kenny MK, Harris CC, Brosh RM. p53 modulates RPA-dependent and RPA-independent WRN helicase activity. Cancer Res. 2005 Feb 15; 65(4):1223-33.
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Sharma S, Sommers JA, Brosh RM. In vivo function of the conserved non-catalytic domain of Werner syndrome helicase in DNA replication. Hum Mol Genet. 2004 Oct 01; 13(19):2247-61.
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Gordon LB, Harten IA, Calabro A, Sugumaran G, Csoka AB, Brown WT, Hascall V, Toole BP. Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome. Hum Genet. 2003 Jul; 113(2):178-87.