DNA Helicases

"DNA Helicases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.

Descriptor ID	D004265
MeSH Number(s)	D08.811.277.040.025.159 D08.811.399.340
Concept/Terms	DNA Helicases DNA Helicases Helicases, DNA DNA Unwinding Proteins Unwinding Proteins, DNA DNA Helicase A DNA Helicase A DNA Helicase II DNA Helicase II DNA Helicase III DNA Helicase III ATP-Dependent DNA Helicases ATP-Dependent DNA Helicases ATP Dependent DNA Helicases DNA Helicases, ATP-Dependent Helicases, ATP-Dependent DNA DNA Helicase E DNA Helicase E

Below are MeSH descriptors whose meaning is more general than "DNA Helicases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
Adenosine Triphosphatases [D08.811.277.040.025]
DNA Helicases [D08.811.277.040.025.159]
Isomerases [D08.811.399]
DNA Helicases [D08.811.399.340]

Below are MeSH descriptors whose meaning is more specific than "DNA Helicases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "DNA Helicases" by people in this website by year, and whether "DNA Helicases" was a major or minor topic of these publications.

Bar chart showing 39 publications over 15 distinct years, with a maximum of 8 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	3	0	3
2004	2	0	2
2005	8	0	8
2006	4	2	6
2007	3	1	4
2008	1	0	1
2009	1	1	2
2011	2	1	3
2012	3	0	3
2013	1	0	1
2018	0	1	1
2020	1	0	1
2022	0	1	1
2023	0	2	2

Below are the most recent publications written about "DNA Helicases" by people in Profiles.

Tarasova E, Khayat R. Dynamics and Conformations of a Full-Length CRESS-DNA Replicase. Viruses. 2023 Dec 08; 15(12).

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Jian Y, Nie L, Liu S, Jiang Y, Dou Z, Liu X, Yao X, Fu C. The fission yeast kinetochore complex Mhf1-Mhf2 regulates the spindle assembly checkpoint and faithful chromosome segregation. J Cell Sci. 2023 01 15; 136(2).

View in: PubMed
Chase J, Berger J, Jeruzalmi D. Convergent evolution in two bacterial replicative helicase loaders. Trends Biochem Sci. 2022 07; 47(7):620-630.

View in: PubMed
Kraithong T, Sucharitakul J, Buranachai C, Jeruzalmi D, Chaiyen P, Pakotiprapha D. Real-time investigation of the roles of ATP hydrolysis by UvrA and UvrB during DNA damage recognition in nucleotide excision repair. DNA Repair (Amst). 2021 01; 97:103024.

View in: PubMed
Adeyemo AA, Zaghloul NA, Chen G, Doumatey AP, Leitch CC, Hostelley TL, Nesmith JE, Zhou J, Bentley AR, Shriner D, Fasanmade O, Okafor G, Eghan B, Agyenim-Boateng K, Chandrasekharappa S, Adeleye J, Balogun W, Owusu S, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C, Collins F, Dunston G, Rotimi CN. ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. Nat Commun. 2019 07 19; 10(1):3195.

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Slavin TP, Neuhausen SL, Nehoray B, Niell-Swiller M, Solomon I, Rybak C, Blazer K, Adamson A, Yang K, Sand S, Guerrero-Llamas N, Castillo D, Herzog J, Wu X, Tao S, Raja S, Chung V, Singh G, Nadesan S, Brown S, Cruz-Correa M, Petersen GM, Weitzel J. The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes. Fam Cancer. 2018 04; 17(2):235-245.

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Araujo LH, Timmers C, Bell EH, Shilo K, Lammers PE, Zhao W, Natarajan TG, Miller CJ, Zhang J, Yilmaz AS, Liu T, Coombes K, Amann J, Carbone DP. Genomic Characterization of Non-Small-Cell Lung Cancer in African Americans by Targeted Massively Parallel Sequencing. J Clin Oncol. 2015 Jun 10; 33(17):1966-73.

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Fatemi M, Paul TA, Brodeur GM, Shokrani B, Brim H, Ashktorab H. Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages. Cancer. 2014 Jan 15; 120(2):172-80.

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Pakotiprapha D, Jeruzalmi D. Small-angle X-ray scattering reveals architecture and A2B2 stoichiometry of the UvrA-UvrB DNA damage sensor. Proteins. 2013 Jan; 81(1):132-9.

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Tao Y, Jin C, Li X, Qi S, Chu L, Niu L, Yao X, Teng M. The structure of the FANCM-MHF complex reveals physical features for functional assembly. Nat Commun. 2012 Apr 17; 3:782.

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