"Steroid 21-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
| Descriptor ID |
D013255
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| MeSH Number(s) |
D08.244.453.493.500 D08.244.453.915.760 D08.811.682.690.708.170.463.500 D08.811.682.690.708.170.915.760 D12.776.422.220.453.493.500 D12.776.422.220.453.915.760
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| Concept/Terms |
Steroid 21-Hydroxylase- Steroid 21-Hydroxylase
- Cytochrome P-450 21-Hydroxylase
- Cytochrome P 450 21 Hydroxylase
- Cytochrome P-450(c-21)
- Progesterone 21-Hydroxylase
- Progesterone 21 Hydroxylase
- Cytochrome P-450 CYP21
- Cytochrome P 450 CYP21
- Steroid 21-Monooxygenase
- Steroid 21 Monooxygenase
- Cytochrome P450c21
- Cytochrome P-450 c21
- Cytochrome P 450 c21
- P-450 c21, Cytochrome
- 21-Hydroxylase
- 21 Hydroxylase
- Steroid-21-Hydroxylase
- Steroid 21 Hydroxylase
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Below are MeSH descriptors whose meaning is more general than "Steroid 21-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 21-Hydroxylase".
This graph shows the total number of publications written about "Steroid 21-Hydroxylase" by people in this website by year, and whether "Steroid 21-Hydroxylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Steroid 21-Hydroxylase" by people in Profiles.
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Schroeder RL, Tram P, Liu J, Foroozesh M, Sridhar J. Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1). Expert Opin Ther Pat. 2016; 26(1):139-47.