RNA Splicing

"RNA Splicing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The ultimate exclusion of nonsense sequences or intervening sequences (introns) before the final RNA transcript is sent to the cytoplasm.

Descriptor ID	D012326
MeSH Number(s)	G02.111.760.700 G03.839.700 G05.308.700.700
Concept/Terms	RNA Splicing RNA Splicing Splicing, RNA RNA Splicings Splicings, RNA RNA, Messenger, Splicing RNA, Messenger, Splicing

Below are MeSH descriptors whose meaning is more general than "RNA Splicing".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
RNA Processing, Post-Transcriptional [G02.111.760]
RNA Splicing [G02.111.760.700]
Metabolism [G03]
RNA Processing, Post-Transcriptional [G03.839]
RNA Splicing [G03.839.700]
Genetic Phenomena [G05]
Gene Expression Regulation [G05.308]
RNA Processing, Post-Transcriptional [G05.308.700]
RNA Splicing [G05.308.700.700]

Below are MeSH descriptors whose meaning is related to "RNA Splicing".

Below are MeSH descriptors whose meaning is more specific than "RNA Splicing".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA Splicing" by people in this website by year, and whether "RNA Splicing" was a major or minor topic of these publications.

Bar chart showing 28 publications over 19 distinct years, with a maximum of 3 publications in 1999 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	2	2
1999	0	3	3
2000	0	1	1
2002	1	0	1
2005	2	1	3
2008	1	1	2
2009	0	1	1
2011	0	1	1
2012	1	0	1
2013	0	1	1
2015	1	1	2
2017	0	1	1
2018	0	1	1
2019	1	0	1
2020	0	1	1
2021	0	2	2
2022	0	1	1
2023	0	1	1
2024	0	2	2

Below are the most recent publications written about "RNA Splicing" by people in Profiles.

Joglekar A, Hu W, Zhang B, Narykov O, Diekhans M, Marrocco J, Balacco J, Ndhlovu LC, Milner TA, Fedrigo O, Jarvis ED, Sheynkman G, Korkin D, Ross ME, Tilgner HU. Single-cell long-read sequencing-based mapping reveals specialized splicing patterns in developing and adult mouse and human brain. Nat Neurosci. 2024 Jun; 27(6):1051-1063.

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Zhang X, Zhan X, Bian T, Yang F, Li P, Lu Y, Xing Z, Fan R, Zhang QC, Shi Y. Structural insights into branch site proofreading by human spliceosome. Nat Struct Mol Biol. 2024 May; 31(5):835-845.

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Sun Y, Bae YE, Zhu J, Zhang Z, Zhong H, Yu J, Wu C, Wu L. A splicing transcriptome-wide association study identifies novel altered splicing for Alzheimer's disease susceptibility. Neurobiol Dis. 2023 08; 184:106209.

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Rabelo-Fern?ndez RJ, Santiago-S?nchez GS, Sharma RK, Roche-Lima A, Carrion KC, Rivera RAN, Qui?ones-D?az BI, Rajasekaran S, Siddiqui J, Miles W, Rivera YS, Valiyeva F, Vivas-Mejia PE. Reduced RBPMS Levels Promote Cell Proliferation and Decrease Cisplatin Sensitivity in Ovarian Cancer Cells. Int J Mol Sci. 2022 Jan 04; 23(1).

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Li D, Liu Y, Yi P, Zhu Z, Li W, Zhang QC, Li JB, Ou G. RNA editing restricts hyperactive ciliary kinases. Science. 2021 08 27; 373(6558):984-991.

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Deveaux AE, Allen TA, Al Abo M, Qin X, Zhang D, Patierno BM, Gu L, Gray JE, Pecot CV, Dressman HK, McCall SJ, Kittles RA, Hyslop T, Owzar K, Crawford J, Patierno SR, Clarke JM, Freedman JA. RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry. Lung Cancer. 2021 03; 153:90-98.

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Chu H, Perea W, Greenbaum NL. Role of the central junction in folding topology of the protein-free human U2-U6 snRNA complex. RNA. 2020 07; 26(7):836-850.

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Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.

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Olender J, Wang BD, Ching T, Garmire LX, Garofano K, Ji Y, Knox T, Latham P, Nguyen K, Rhim J, Lee NH. A Novel FGFR3 Splice Variant Preferentially Expressed in African American Prostate Cancer Drives Aggressive Phenotypes and Docetaxel Resistance. Mol Cancer Res. 2019 10; 17(10):2115-2125.

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Uzzan M, Tokuyama M, Rosenstein AK, Tomescu C, SahBandar IN, Ko HM, Leyre L, Chokola A, Kaplan-Lewis E, Rodriguez G, Seki A, Corley MJ, Aberg J, La Porte A, Park EY, Ueno H, Oikonomou I, Doron I, Iliev ID, Chen BK, Lui J, Schacker TW, Furtado GC, Lira SA, Colombel JF, Horowitz A, Lim JK, Chomont N, Rahman AH, Montaner LJ, Ndhlovu LC, Mehandru S. Anti-a4?7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals. Sci Transl Med. 2018 10 03; 10(461).

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