Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration.

Wang ER, Jarrah AA, Benard L, Chen J, Schwarzkopf M, Hadri L, Tarzami ST. Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration. Gene Ther. 2014 May; 21(5):496-506.

View in: PubMed

subject areas

Adrenergic beta-Agonists
Animals
Apoptosis
Cardiomegaly
Cardiotonic Agents
Chemokine CXCL12
Dependovirus
Fibrosis
Gene Knockout Techniques
Gene Transfer Techniques
Genetic Vectors
Glycogen Synthase Kinase 3
Heart Failure
Isoproterenol
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitochondria
Myocytes, Cardiac
Receptors, Adrenergic, beta
Receptors, CXCR4
Signal Transduction
Stroke Volume

authors with profiles

Sima Tarzami

RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

For technical support please contact support