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Sima Tarzami

TitleAssociate Professor
Faculty RankAssociate Professor
InstitutionHoward University
DepartmentPhysiology & Biophysics
Address520 W Street, NW, Suite 2420
Washington DC 20059
Phone2028065269
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bisserier M, Mathiyalagan P, Zhang S, Elmastour F, Dorfm?ller P, Humbert M, David G, Tarzami S, Weber T, Perros F, Sassi Y, Sahoo S, Hadri L. Regulation of the Methylation and Expression Levels of the BMPR2 Gene by SIN3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension. Circulation. 2021 07 06; 144(1):52-73. PMID: 34078089.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    2. Bisserier M, Milara J, Abdeldjebbar Y, Gubara S, Jones C, Bueno-Beti C, Chepurko E, Kohlbrenner E, Katz MG, Tarzami S, Cortijo J, Leopold J, Hajjar RJ, Sassi Y, Hadri L. AAV1.SERCA2a Gene Therapy Reverses Pulmonary Fibrosis by Blocking the STAT3/FOXM1 Pathway and Promoting the SNON/SKI Axis. Mol Ther. 2020 02 05; 28(2):394-410. PMID: 31879190.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    3. LaRocca TJ, Altman P, Jarrah AA, Gordon R, Wang E, Hadri L, Burke MW, Haddad GE, Hajjar RJ, Tarzami ST. CXCR4 Cardiac Specific Knockout Mice Develop a Progressive Cardiomyopathy. Int J Mol Sci. 2019 May 08; 20(9). PMID: 31071921.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    4. Obad A, Peeran A, Little JI, Haddad GE, Tarzami ST. Alcohol-Mediated Organ Damages: Heart and Brain. Front Pharmacol. 2018; 9:81. PMID: 29487525.
      Citations:    
    5. Jarrah AA, Schwarskopf M, Wang ER, LaRocca T, Dhume A, Zhang S, Hadri L, Hajjar RJ, Schecter AD, Tarzami ST. SDF-1 induces TNF-mediated apoptosis in cardiac myocytes. Apoptosis. 2018 01; 23(1):79-91. PMID: 29236198.
      Citations: 32     Fields:    Translation:AnimalsCells
    6. Ceholski DK, Turnbull IC, Pothula V, Lecce L, Jarrah AA, Kho C, Lee A, Hadri L, Costa KD, Hajjar RJ, Tarzami ST. CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic ?-adrenergic response. Stem Cell Res. 2017 08; 23:77-86. PMID: 28711757.
      Citations: 13     Fields:    Translation:HumansCells
    7. Jarrah AA, Tarzami ST. The duality of chemokines in heart failure. Expert Rev Clin Immunol. 2015 Apr; 11(4):523-36. PMID: 25764001.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Wang ER, Jarrah AA, Benard L, Chen J, Schwarzkopf M, Hadri L, Tarzami ST. Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration. Gene Ther. 2014 May; 21(5):496-506. PMID: 24646609.
      Citations: 16     Fields:    Translation:AnimalsCells
    9. Lipskaia L, Bobe R, Chen J, Turnbull IC, Lopez JJ, Merlet E, Jeong D, Karakikes I, Ross AS, Liang L, Mougenot N, Atassi F, Lompr? AM, Tarzami ST, Kovacic JC, Kranias E, Hajjar RJ, Hadri L. Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells. Circulation. 2014 Feb 18; 129(7):773-85. PMID: 24249716.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    10. Larocca TJ, Jeong D, Kohlbrenner E, Lee A, Chen J, Hajjar RJ, Tarzami ST. CXCR4 gene transfer prevents pressure overload induced heart failure. J Mol Cell Cardiol. 2012 Aug; 53(2):223-32. PMID: 22668785.
      Citations: 19     Fields:    Translation:AnimalsCells
    11. Tarzami ST. Chemokines and inflammation in heart disease: adaptive or maladaptive? Int J Clin Exp Med. 2011; 4(1):74-80. PMID: 21394288.
      Citations:    
    12. LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST. ?2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4. J Cardiovasc Pharmacol. 2010 Nov; 56(5):548-59. PMID: 20729750.
      Citations: 41     Fields:    Translation:AnimalsCells
    13. Chen J, Chemaly E, Liang L, Kho C, Lee A, Park J, Altman P, Schecter AD, Hajjar RJ, Tarzami ST. Effects of CXCR4 gene transfer on cardiac function after ischemia-reperfusion injury. Am J Pathol. 2010 Apr; 176(4):1705-15. PMID: 20133817.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    14. Lipsky R, Potts EM, Tarzami ST, Puckerin AA, Stocks J, Schecter AD, Sobie EA, Akar FG, Divers?-Pierluissi MA. beta-Adrenergic receptor activation induces internalization of cardiac Cav1.2 channel complexes through a beta-arrestin 1-mediated pathway. J Biol Chem. 2008 Jun 20; 283(25):17221-6. PMID: 18458091.
      Citations: 11     Fields:    Translation:AnimalsCells
    15. Tarzami ST, Wang G, Li W, Green L, Singh JP. Thrombin and PAR-1 stimulate differentiation of bone marrow-derived endothelial progenitor cells. J Thromb Haemost. 2006 Mar; 4(3):656-63. PMID: 16460448.
      Citations: 12     Fields:    Translation:AnimalsCells
    16. Tarzami ST, Calderon TM, Deguzman A, Lopez L, Kitsis RN, Berman JW. MCP-1/CCL2 protects cardiac myocytes from hypoxia-induced apoptosis by a G(alphai)-independent pathway. Biochem Biophys Res Commun. 2005 Oct 07; 335(4):1008-16. PMID: 16102724.
      Citations: 32     Fields:    Translation:AnimalsCells
    17. Tarzami ST, Hsieh SS, Esterman MA, Singh JP. Staurosporine promotes endothelial cell assembly and FAK phosphorylation during in vitro angiogenesis. J Cardiovasc Pharmacol. 2005 Jan; 45(1):22-9. PMID: 15613975.
      Citations: 1     Fields:    Translation:HumansCells
    18. Tarzami ST, Singh JP. Pharmacological revascularisation in coronary and peripheral vascular disease. Expert Opin Investig Drugs. 2004 Oct; 13(10):1319-26. PMID: 15461560.
      Citations:    Fields:    Translation:HumansAnimals
    19. Tarzami ST, Miao W, Mani K, Lopez L, Factor SM, Berman JW, Kitsis RN. Opposing effects mediated by the chemokine receptor CXCR2 on myocardial ischemia-reperfusion injury: recruitment of potentially damaging neutrophils and direct myocardial protection. Circulation. 2003 Nov 11; 108(19):2387-92. PMID: 14568904.
      Citations: 33     Fields:    Translation:AnimalsCells
    20. Tarzami ST, Cheng R, Miao W, Kitsis RN, Berman JW. Chemokine expression in myocardial ischemia: MIP-2 dependent MCP-1 expression protects cardiomyocytes from cell death. J Mol Cell Cardiol. 2002 Feb; 34(2):209-21. PMID: 11851360.
      Citations: 36     Fields:    Translation:AnimalsCells
    21. Jiang Y, Tarzami S, Burch JB, Evans T. Common role for each of the cGATA-4/5/6 genes in the regulation of cardiac morphogenesis. Dev Genet. 1998; 22(3):263-77. PMID: 9621433.
      Citations: 16     Fields:    Translation:AnimalsCells
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