"Immunoglobulin mu-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The class of heavy chains found in IMMUNOGLOBULIN M. They have a molecular weight of approximately 72 kDa and they contain about 57 amino acid residues arranged in five domains and have more oligosaccharide branches and a higher carbohydrate content than the heavy chains of IMMUNOGLOBULIN G.
Descriptor ID |
D007148
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MeSH Number(s) |
D12.776.124.486.485.114.619.574.500 D12.776.124.486.485.705.500.500 D12.776.124.790.651.114.619.574.500 D12.776.124.790.651.705.500.500 D12.776.377.715.548.114.619.574.500 D12.776.377.715.548.705.500.500
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Concept/Terms |
Immunoglobulin mu-Chains- Immunoglobulin mu-Chains
- Immunoglobulin mu Chains
- mu-Chains, Immunoglobulin
- mu-Chain Immunoglobulins
- mu Chain Immunoglobulins
- mu Immunoglobulin Heavy Chain
- mu Immunoglobulin Heavy Chains
- Immunoglobulin mu-Chain
- Immunoglobulin mu Chain
- mu-Chain, Immunoglobulin
- Immunoglobulins, mu-Chain
- Immunoglobulins, mu Chain
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin mu-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin mu-Chains".
This graph shows the total number of publications written about "Immunoglobulin mu-Chains" by people in this website by year, and whether "Immunoglobulin mu-Chains" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin mu-Chains" by people in Profiles.
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Aihara N, Chambers JK, Hosono K, Kamiie J, Shirota K. An experimental type II mixed cryoglobulinemia with renal glomerulopathy in ICR mice triggered by Capillaria hepatica infection. Histol Histopathol. 2011 12; 26(12):1519-29.
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Li F, Eckhardt LA. A role for the IgH intronic enhancer E mu in enforcing allelic exclusion. J Exp Med. 2009 Jan 16; 206(1):153-67.
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Zeng X, Negrete GA, Kasmer C, Yang WW, Gearhart PJ. Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions. J Exp Med. 2004 Apr 05; 199(7):917-24.
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Lieberson R, Ong J, Shi X, Eckhardt LA. Immunoglobulin gene transcription ceases upon deletion of a distant enhancer. EMBO J. 1995 Dec 15; 14(24):6229-38.
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Shen L, Lieberman S, Eckhardt LA. The octamer/mu E4 region of the immunoglobulin heavy-chain enhancer mediates gene repression in myeloma x T-lymphoma hybrids. Mol Cell Biol. 1993 Jun; 13(6):3530-40.
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Spatz LA, Wong KK, Williams M, Desai R, Golier J, Berman JE, Alt FW, Latov N. Cloning and sequence analysis of the VH and VL regions of an anti-myelin/DNA antibody from a patient with peripheral neuropathy and chronic lymphocytic leukemia. J Immunol. 1990 Apr 01; 144(7):2821-8.