Genes, Immunoglobulin Heavy Chain
"Genes, Immunoglobulin Heavy Chain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes and gene segments encoding the IMMUNOGLOBULIN HEAVY CHAINS. Gene segments of the heavy chain genes are symbolized V (variable), D (diversity), J (joining), and C (constant).
| Descriptor ID |
D050438
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| MeSH Number(s) |
G05.360.340.024.340.335.300
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Genes, Immunoglobulin Heavy Chain".
Below are MeSH descriptors whose meaning is more specific than "Genes, Immunoglobulin Heavy Chain".
This graph shows the total number of publications written about "Genes, Immunoglobulin Heavy Chain" by people in this website by year, and whether "Genes, Immunoglobulin Heavy Chain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, Immunoglobulin Heavy Chain" by people in Profiles.
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Watson CT, Steinberg KM, Graves TA, Warren RL, Malig M, Schein J, Wilson RK, Holt RA, Eichler EE, Breden F. Sequencing of the human IG light chain loci from a hydatidiform mole BAC library reveals locus-specific signatures of genetic diversity. Genes Immun. 2015 Jan-Feb; 16(1):24-34.
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Peng C, Eckhardt LA. Role of the Igh intronic enhancer E? in clonal selection at the pre-B to immature B cell transition. J Immunol. 2013 Oct 15; 191(8):4399-411.
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Watson CT, Steinberg KM, Huddleston J, Warren RL, Malig M, Schein J, Willsey AJ, Joy JB, Scott JK, Graves TA, Wilson RK, Holt RA, Eichler EE, Breden F. Complete haplotype sequence of the human immunoglobulin heavy-chain variable, diversity, and joining genes and characterization of allelic and copy-number variation. Am J Hum Genet. 2013 Apr 04; 92(4):530-46.
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Shiramizu B, Goldman S, Kusao I, Agsalda M, Lynch J, Smith L, Harrison L, Morris E, Gross TG, Sanger W, Perkins S, Cairo MS. Minimal disease assessment in the treatment of children and adolescents with intermediate-risk (Stage III/IV) B-cell non-Hodgkin lymphoma: a children's oncology group report. Br J Haematol. 2011 Jun; 153(6):758-63.
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Li F, Yan Y, Pieretti J, Feldman DA, Eckhardt LA. Comparison of identical and functional Igh alleles reveals a nonessential role for E? in somatic hypermutation and class-switch recombination. J Immunol. 2010 Nov 15; 185(10):6049-57.
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Li F, Eckhardt LA. A role for the IgH intronic enhancer E mu in enforcing allelic exclusion. J Exp Med. 2009 Jan 16; 206(1):153-67.