Immunoglobulin gamma-Chains
"Immunoglobulin gamma-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heavy chains of IMMUNOGLOBULIN G having a molecular weight of approximately 51 kDa. They contain about 450 amino acid residues arranged in four domains and an oligosaccharide component covalently bound to the Fc fragment constant region. The gamma heavy chain subclasses (for example, gamma 1, gamma 2a, and gamma 2b) of the IMMUNOGLOBULIN G isotype subclasses (IgG1, IgG2A, and IgG2B) resemble each other more closely than the heavy chains of the other IMMUNOGLOBULIN ISOTYPES.
| Descriptor ID |
D007142
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| MeSH Number(s) |
D12.776.124.486.485.114.619.393.522 D12.776.124.486.485.705.500.380 D12.776.124.790.651.114.619.393.522 D12.776.124.790.651.705.500.380 D12.776.377.715.548.114.619.393.522 D12.776.377.715.548.705.500.380
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| Concept/Terms |
Immunoglobulin gamma-Chains- Immunoglobulin gamma-Chains
- Immunoglobulin gamma Chains
- gamma-Chains, Immunoglobulin
- Immunoglobulins, gamma-Chain
- Immunoglobulins, gamma Chain
- gamma-Chain Immunoglobulins
- gamma Chain Immunoglobulins
- Immunoglobulin gamma-Chain
- Immunoglobulin gamma Chain
- gamma-Chain, Immunoglobulin
- gamma Immunoglobulin Heavy Chain
- gamma Immunoglobulin Heavy Chains
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin gamma-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin gamma-Chains".
This graph shows the total number of publications written about "Immunoglobulin gamma-Chains" by people in this website by year, and whether "Immunoglobulin gamma-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin gamma-Chains" by people in Profiles.
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Zeng X, Negrete GA, Kasmer C, Yang WW, Gearhart PJ. Absence of DNA polymerase eta reveals targeting of C mutations on the nontranscribed strand in immunoglobulin switch regions. J Exp Med. 2004 Apr 05; 199(7):917-24.
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Radomska HS, Shen CP, Kadesch T, Eckhardt LA. Constitutively expressed Oct-2 prevents immunoglobulin gene silencing in myeloma x T cell hybrids. Immunity. 1994 Nov; 1(8):623-34.
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Porton B, Zaller DM, Lieberson R, Eckhardt LA. Immunoglobulin heavy-chain enhancer is required to maintain transfected gamma 2A gene expression in a pre-B-cell line. Mol Cell Biol. 1990 Mar; 10(3):1076-83.
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Zaller DM, Eckhardt LA. Deletion of a B-cell-specific enhancer affects transfected, but not endogenous, immunoglobulin heavy-chain gene expression. Proc Natl Acad Sci U S A. 1985 Aug; 82(15):5088-92.
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Tilley SA, Eckhardt LA, Marcu KB, Birshtein BK. Hybrid gamma 2b-gamma 2a genes expressed in myeloma variants: evidence for homologous recombination. Proc Natl Acad Sci U S A. 1983 Nov; 80(22):6967-71.
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Eckhardt LA, Tilley SA, Lang RB, Marcu KB, Birshtein BK. DNA rearrangements in MPC-11 immunoglobulin heavy chain class-switch variants. Proc Natl Acad Sci U S A. 1982 May; 79(9):3006-10.