"Complement Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The sequential activation of serum COMPLEMENT PROTEINS to create the COMPLEMENT MEMBRANE ATTACK COMPLEX. Factors initiating complement activation include ANTIGEN-ANTIBODY COMPLEXES, microbial ANTIGENS, or cell surface POLYSACCHARIDES.
| Descriptor ID |
D003167
|
| MeSH Number(s) |
G12.274
|
| Concept/Terms |
Complement Activation- Complement Activation
- Activation, Complement
- Activations, Complement
- Complement Activations
|
Below are MeSH descriptors whose meaning is more general than "Complement Activation".
Below are MeSH descriptors whose meaning is more specific than "Complement Activation".
This graph shows the total number of publications written about "Complement Activation" by people in this website by year, and whether "Complement Activation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Complement Activation" by people in Profiles.
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Sullivan KE. The yin and the yang of early classical pathway complement disorders. Clin Exp Immunol. 2022 08 19; 209(2):151-160.
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Manral P, Caza TN, Storey AJ, Beck LH, Borza DB. The Alternative Pathway Is Necessary and Sufficient for Complement Activation by Anti-THSD7A Autoantibodies, Which Are Predominantly IgG4 in Membranous Nephropathy. Front Immunol. 2022; 13:952235.
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Borza DB. Glomerular basement membrane heparan sulfate in health and disease: A regulator of local complement activation. Matrix Biol. 2017 01; 57-58:299-310.
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Hew BE, Wehrhahn D, Fritzinger DC, Vogel CW. Hybrid proteins of Cobra Venom Factor and cobra C3: tools to identify functionally important regions in Cobra Venom Factor. Toxicon. 2012 Sep 15; 60(4):632-47.
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L?pez de Victoria A, Gorham RD, Bellows-Peterson ML, Ling J, Lo DD, Floudas CA, Morikis D. A new generation of potent complement inhibitors of the Compstatin family. Chem Biol Drug Des. 2011 Jun; 77(6):431-40.
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Pacheco LD, Hankins GD, Costantine MM, Anderson GD, Pawelczyk E, Nowicki S, Nowicki BJ. The role of human decay-accelerating factor in the pathogenesis of preterm labor. Am J Perinatol. 2011 Aug; 28(7):565-70.
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Hu W, Yu Q, Hu N, Byrd D, Amet T, Shikuma C, Shiramizu B, Halperin JA, Qin X. A high-affinity inhibitor of human CD59 enhances complement-mediated virolysis of HIV-1: implications for treatment of HIV-1/AIDS. J Immunol. 2010 Jan 01; 184(1):359-68.
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Bloch EF, Morrison K, McDonald-Pinkett S, Baskin S, Campbell S, Peters S, Dillahunt S, Evans D, Lucas S, Macatangay A, Kanaan Y. The deposition of C5b-9 complexes and its precursors on E. coli J5 during complement activation enhances uptake and toxicities of gentamicin. Immunol Invest. 2008; 37(3):245-61.
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Vogel CW, Fritzinger DC, Hew BE, Thorne M, Bammert H. Recombinant cobra venom factor. Mol Immunol. 2004 Jun; 41(2-3):191-9.
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Orudzhev AG, Guseinova EE, Khalilova IS, Dzhavadov SA. [Assessment of endogenous intoxication and thrombocyte functions in beta-thalassemia]. Klin Lab Diagn. 2003 Mar; (3):39-41.