Antibody-Dependent Enhancement
"Antibody-Dependent Enhancement" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by Fc receptors (RECEPTORS, FC) or by complement receptors (RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral IMMUNOGLOBULIN G and binds to Fc receptors, or virus is coated with antiviral IMMUNOGLOBULIN M and binds to complement receptors.
| Descriptor ID |
D019067
|
| MeSH Number(s) |
G06.920.095 G12.113
|
| Concept/Terms |
Antibody-Dependent Enhancement- Antibody-Dependent Enhancement
- Antibody Dependent Enhancement
- Antibody-Dependent Enhancements
- Enhancement, Antibody-Dependent
|
Below are MeSH descriptors whose meaning is more general than "Antibody-Dependent Enhancement".
Below are MeSH descriptors whose meaning is more specific than "Antibody-Dependent Enhancement".
This graph shows the total number of publications written about "Antibody-Dependent Enhancement" by people in this website by year, and whether "Antibody-Dependent Enhancement" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antibody-Dependent Enhancement" by people in Profiles.
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Garg H, Yeh R, Watts DM, Mehmetoglu-Gurbuz T, Resendes R, Parsons B, Gonzales F, Joshi A. Enhancement of Zika virus infection by antibodies from West Nile virus seropositive individuals with no history of clinical infection. BMC Immunol. 2021 01 09; 22(1):5.
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Sariol CA, Nogueira ML, Vasilakis N. A Tale of Two Viruses: Does Heterologous Flavivirus Immunity Enhance Zika Disease? Trends Microbiol. 2018 03; 26(3):186-190.
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Pantoja P, P?rez-Guzm?n EX, Rodr?guez IV, White LJ, Gonz?lez O, Serrano C, Giavedoni L, Hodara V, Cruz L, Arana T, Mart?nez MI, Hassert MA, Brien JD, Pinto AK, de Silva A, Sariol CA. Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus. Nat Commun. 2017 06 23; 8:15674.