Virus Latency

"Virus Latency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The ability of a pathogenic virus to lie dormant within a cell (latent infection). In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. Latency in bacteriophage is maintained by the expression of virally encoded repressors.

Descriptor ID	D017735
MeSH Number(s)	G06.920.900
Concept/Terms	Virus Latency Virus Latency Latencies, Virus Latency, Virus Virus Latencies Viral Latency Latencies, Viral Latency, Viral Viral Latencies

Below are MeSH descriptors whose meaning is more general than "Virus Latency".

Biological Sciences [G]
Microbiological Phenomena [G06]
Virus Physiological Phenomena [G06.920]
Virus Latency [G06.920.900]

Below are MeSH descriptors whose meaning is related to "Virus Latency".

Below are MeSH descriptors whose meaning is more specific than "Virus Latency".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Virus Latency" by people in this website by year, and whether "Virus Latency" was a major or minor topic of these publications.

Bar chart showing 33 publications over 16 distinct years, with a maximum of 4 publications in 2003 and 2008 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	2	2	4
2006	1	0	1
2007	0	1	1
2008	3	1	4
2009	0	1	1
2010	0	2	2
2011	3	0	3
2012	2	0	2
2013	1	0	1
2015	0	1	1
2016	2	0	2
2017	1	1	2
2019	0	4	4
2021	0	2	2
2023	0	2	2

Below are the most recent publications written about "Virus Latency" by people in Profiles.

Lyons DE, Kumar P, Roan NR, Defechereux PA, Feschotte C, Lange UC, Murthy N, Sameshima P, Verdin E, Ake JA, Parsons MS, Nath A, Gianella S, Smith DM, Kallas EG, Villa TJ, Strange R, Mwesigwa B, Furler O'Brien RL, Nixon DF, Ndhlovu LC, Valente ST, Ott M. HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing. Viruses. 2023 10 28; 15(11).

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Moar P, Premeaux TA, Atkins A, Ndhlovu LC. The latent HIV reservoir: current advances in genetic sequencing approaches. mBio. 2023 Oct 31; 14(5):e0134423.

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Corley MJ, Pang APS, Rasmussen TA, Tolstrup M, S?gaard OS, Ndhlovu LC. Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound. AIDS. 2021 11 15; 35(14):2269-2279.

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Shytaj IL, Procopio FA, Tarek M, Carlon-Andres I, Tang HY, Goldman AR, Munshi M, Kumar Pal V, Forcato M, Sreeram S, Leskov K, Ye F, Lucic B, Cruz N, Ndhlovu LC, Bicciato S, Padilla-Parra S, Diaz RS, Singh A, Lusic M, Karn J, Alvarez-Carbonell D, Savarino A. Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress. EMBO Mol Med. 2021 08 09; 13(8):e13901.

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Mitchell BI, Laws EI, Ndhlovu LC. Impact of Myeloid Reservoirs in HIV Cure Trials. Curr HIV/AIDS Rep. 2019 04; 16(2):129-140.

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Hu M, Armstrong N, Seto E, Li W, Zhu F, Wang PC, Tang Q. Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA. J Virol. 2019 04 01; 93(7).

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Colomb F, Giron LB, Premeaux TA, Mitchell BI, Niki T, Papasavvas E, Montaner LJ, Ndhlovu LC, Abdel-Mohsen M. Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling. Front Immunol. 2019; 10:267.

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McNamara RP, Chugh PE, Bailey A, Costantini LM, Ma Z, Bigi R, Cheves A, Eason AB, Landis JT, Host KM, Xiong J, Griffith JD, Damania B, Dittmer DP. Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming. PLoS Pathog. 2019 02; 15(2):e1007536.

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Host KM, Jacobs SR, West JA, Zhang Z, Costantini LM, Stopford CM, Dittmer DP, Damania B. Kaposi's Sarcoma-Associated Herpesvirus Increases PD-L1 and Proinflammatory Cytokine Expression in Human Monocytes. mBio. 2017 10 10; 8(5).

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Cheng S, Jiang X, Yang B, Wen L, Zhao F, Zeng WB, Liu XJ, Dong X, Sun JY, Ming YZ, Zhu H, Rayner S, Tang Q, Fortunato E, Luo MH. Infected T98G glioblastoma cells support human cytomegalovirus reactivation from latency. Virology. 2017 10; 510:205-215.

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