"Biguanides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES.
Descriptor ID |
D001645
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MeSH Number(s) |
D02.078.370.141
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Biguanides".
Below are MeSH descriptors whose meaning is more specific than "Biguanides".
This graph shows the total number of publications written about "Biguanides" by people in this website by year, and whether "Biguanides" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Biguanides" by people in Profiles.
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Nabeela S, Date A, Ibrahim AS, Uppuluri P. Antifungal activity of alexidine dihydrochloride in a novel diabetic mouse model of dermatophytosis. Front Cell Infect Microbiol. 2022; 12:958497.
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Ike A, Shirai K, Nishikawa H, Iwata A, Yahiro E, Sugihara M, Kawamura A, Uehara Y, Zhang B, Ogawa M, Mori K, Miura S, Saku K. Associations between different types of hypoglycemic agents and the clinical outcome of percutaneous coronary intervention in diabetic patients-From the FU-Registry. J Cardiol. 2015 May; 65(5):390-6.
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Dougherty JJ, Nichols RA. Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals. Acta Pharmacol Sin. 2009 Jun; 30(6):788-94.
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Ohia SE, Awe SO, Opere CA, LeDay AM, Harris LC, Kulkarni K, Sharif NA. Glucose-deprivation-induced [3H]D-aspartate release from isolated bovine and human retinae. J Ocul Pharmacol Ther. 2003 Dec; 19(6):599-609.
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Harris LC, Awe SO, Opere CA, LeDay AM, Ohia SE, Sharif NA. Pharmacology of serotonin receptors modulating electrically-induced [3h]-norepinephrine release from isolated mammalian iris-ciliary bodies. J Ocul Pharmacol Ther. 2002 Aug; 18(4):339-48.
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Rond? P, Nichols RA. Postsynaptic target regulates functional responses induced by 5-HT3 serotonin receptors on axonal varicosities of NG108-15 hybrid neuroblastoma cells. Neuroscience. 2001; 102(4):979-87.
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Nayak SV, Rond? P, Spier AD, Lummis SC, Nichols RA. Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals. Neuropharmacology. 2000 Oct; 39(13):2681-90.