"Receptors, Nicotinic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major classes of cholinergic receptors. Nicotinic receptors were originally distinguished by their preference for NICOTINE over MUSCARINE. They are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
| Descriptor ID |
D011978
|
| MeSH Number(s) |
D12.776.157.530.400.400.100.500 D12.776.543.550.450.500.100.500 D12.776.543.585.400.500.100.500 D12.776.543.750.130.687 D12.776.543.750.720.360.550
|
| Concept/Terms |
Receptors, Nicotinic- Receptors, Nicotinic
- Nicotinic Receptors
- Nicotinic Acetylcholine Receptors
- Acetylcholine Receptors, Nicotinic
- Receptors, Nicotinic Acetylcholine
- Nicotinic Acetylcholine Receptor
- Acetylcholine Receptor, Nicotinic
- Receptor, Nicotinic Acetylcholine
- Nicotinic Receptor
- Receptor, Nicotinic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Nicotinic".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.157.530.400.400.100]
- Receptors, Nicotinic [D12.776.157.530.400.400.100.500]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.450]
- Ligand-Gated Ion Channels [D12.776.543.550.450.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.550.450.500.100]
- Receptors, Nicotinic [D12.776.543.550.450.500.100.500]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.585.400.500.100]
- Receptors, Nicotinic [D12.776.543.585.400.500.100.500]
- Receptors, Cell Surface [D12.776.543.750]
- Cysteine Loop Ligand-Gated Ion Channel Receptors [D12.776.543.750.130]
- Receptors, Nicotinic [D12.776.543.750.130.687]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Cholinergic [D12.776.543.750.720.360]
- Receptors, Nicotinic [D12.776.543.750.720.360.550]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Nicotinic".
This graph shows the total number of publications written about "Receptors, Nicotinic" by people in this website by year, and whether "Receptors, Nicotinic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 3 | 0 | 3 |
| 2001 | 4 | 1 | 5 |
| 2002 | 4 | 1 | 5 |
| 2003 | 2 | 1 | 3 |
| 2004 | 6 | 0 | 6 |
| 2005 | 6 | 1 | 7 |
| 2006 | 3 | 1 | 4 |
| 2007 | 5 | 0 | 5 |
| 2008 | 6 | 1 | 7 |
| 2009 | 6 | 0 | 6 |
| 2010 | 3 | 2 | 5 |
| 2011 | 2 | 1 | 3 |
| 2012 | 4 | 1 | 5 |
| 2013 | 1 | 1 | 2 |
| 2015 | 3 | 0 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 0 | 1 | 1 |
| 2020 | 3 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Nicotinic" by people in Profiles.
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Roberts CF, Cao Y, Im W, Nichols RA, Lukas RJ, George AA. Neuroprotective amyloid ? N-terminal peptides differentially alter human a7- and a7?2-nicotinic acetylcholine (nACh) receptor single-channel properties. Br J Pharmacol. 2024 Sep; 181(17):3172-3191.
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Wiere S, Sugai C, Espiritu MJ, Aurelio VP, Reyes CD, Yuzon N, Whittal RM, Tytgat J, Peigneur S, Bingham JP. Research into the Bioengineering of a Novel a-Conotoxin from the Milked Venom of Conus obscurus. Int J Mol Sci. 2022 Oct 11; 23(20).
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Giner P, Maynez-Anchondo L, Liley AE, Uribe KP, Frietze GA, Simon NW, Mendez IA. Increased Risky Choice and Reduced CHRNB2 Expression in Adult Male Rats Exposed to Nicotine Vapor. Int J Mol Sci. 2022 Jan 22; 23(3).
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Roberts JP, Stokoe SA, Sathler MF, Nichols RA, Kim S. Selective coactivation of a7- and a4?2-nicotinic acetylcholine receptors reverses beta-amyloid-induced synaptic dysfunction. J Biol Chem. 2021 Jan-Jun; 296:100402.
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Tizabi Y, Getachew B, Copeland RL, Aschner M. Nicotine and the nicotinic cholinergic system in COVID-19. FEBS J. 2020 09; 287(17):3656-3663.
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Arora K, Belcaid M, Lantz MJ, Taketa R, Nichols RA. Transcriptome Profile of Nicotinic Receptor-Linked Sensitization of Beta Amyloid Neurotoxicity. Sci Rep. 2020 03 30; 10(1):5696.
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Shao XM, Fang ZT. Severe Acute Toxicity of Inhaled Nicotine and e-Cigarettes: Seizures and Cardiac Arrhythmia. Chest. 2020 03; 157(3):506-508.
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Reale M, D'Angelo C, Costantini E, Di Nicola M, Yarla NS, Kamal MA, Salvador N, Perry G. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology. J Alzheimers Dis. 2018; 62(1):467-476.
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Shao XM, L?pez-Vald?s HE, Liang J, Feldman JL. Inhaled nicotine equivalent to cigarette smoking disrupts systemic and uterine hemodynamics and induces cardiac arrhythmia in pregnant rats. Sci Rep. 2017 12 05; 7(1):16974.
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Leffler AE, Kuryatov A, Zebroski HA, Powell SR, Filipenko P, Hussein AK, Gorson J, Heizmann A, Lyskov S, Tsien RW, Poget SF, Nicke A, Lindstrom J, Rudy B, Bonneau R, Holford M. Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):E8100-E8109.