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Jesse B. Owens, Ph.D.

Title
Faculty RankAssistant Research Professor
InstitutionUniversity of Hawaii at Manoa
DepartmentAnatomy, Biochemistry & Physiology
AddressInstitute for Biogenesis Research
University of Hawaii at Manoa
1960 East-West Rd
Honolulu HI 96822
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    Collapse Research 
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    R21GM132779     (OWENS, JESSE B)Jun 1, 2019 - Feb 28, 2021
    NIH
    Development of a novel genome targeting technology using rational design and continuous evolution.
    Role: Principal Investigator
    R01EB031124     (OWENS, JESSE B)May 1, 2021 - Jan 31, 2025
    NIH
    Directed evolution of a sequence-specific targeting technology for therapeutic gene delivery to the human genome.
    Role: Principal Investigator
    R01GM160155     (OWENS, JESSE BRUCE)Sep 8, 2025 - Jun 30, 2029
    NIH
    Development of a Targetable Transposase Platform for Precision Gene Integration in Human Cells
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hew BE, Gupta S, Sato R, Waller DF, Stoytchev I, Short JE, Sharek L, Tran CT, Badran AH, Owens JB. Directed evolution of hyperactive integrases for site specific insertion of transgenes. Nucleic Acids Res. 2024 Aug 12; 52(14):e64. PMID: 38953167.
      Citations: 7     Fields:    Translation:HumansCells
    2. Hew BE, Gupta S, Sato R, Waller DF, Stoytchev I, Short JE, Sharek L, Tran CT, Badran AH, Owens JB. Directed evolution of hyperactive integrases for site specific insertion of transgenes. bioRxiv. 2024 Jun 11. PMID: 38915697.
      Citations:    
    3. Hew BE, Sato R, Mauro D, Stoytchev I, Owens JB. RNA-guided piggyBac transposition in human cells. Synth Biol (Oxf). 2019; 4(1):ysz018. PMID: 31355344.
      Citations:    
    4. Davy PM, Lye KD, Mathews J, Owens JB, Chow AY, Wong L, Moisyadi S, Allsopp RC. Human adipose stem cell and ASC-derived cardiac progenitor cellular therapy improves outcomes in a murine model of myocardial infarction. Stem Cells Cloning. 2015; 8:135-48. PMID: 26604802.
      Citations:    
    5. Owens JB, Mauro D, Stoytchev I, Bhakta MS, Kim MS, Segal DJ, Moisyadi S. Transcription activator like effector (TALE)-directed piggyBac transposition in human cells. Nucleic Acids Res. 2013 Oct; 41(19):9197-207. PMID: 23921635.
      Citations: 35     Fields:    Translation:HumansCells
    6. Owens JB, Urschitz J, Stoytchev I, Dang NC, Stoytcheva Z, Belcaid M, Maragathavally KJ, Coates CJ, Segal DJ, Moisyadi S. Chimeric piggyBac transposases for genomic targeting in human cells. Nucleic Acids Res. 2012 Aug; 40(14):6978-91. PMID: 22492708.
      Citations: 28     Fields:    Translation:HumansCells
    7. Urschitz J, Kawasumi M, Owens J, Morozumi K, Yamashiro H, Stoytchev I, Marh J, Dee JA, Kawamoto K, Coates CJ, Kaminski JM, Pelczar P, Yanagimachi R, Moisyadi S. Helper-independent piggyBac plasmids for gene delivery approaches: strategies for avoiding potential genotoxic effects. Proc Natl Acad Sci U S A. 2010 May 04; 107(18):8117-22. PMID: 20404201.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
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