"Angiotensinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively.
| Descriptor ID |
D000808
|
| MeSH Number(s) |
D12.644.456.073.070 D12.644.861.020 D12.776.811.070 D12.776.872.020
|
| Concept/Terms |
Angiotensinogen- Angiotensinogen
- Serpin A8
- Renin-Substrate
- Renin Substrate
- Hypertensinogen
- Proangiotensin
|
Below are MeSH descriptors whose meaning is more general than "Angiotensinogen".
Below are MeSH descriptors whose meaning is more specific than "Angiotensinogen".
This graph shows the total number of publications written about "Angiotensinogen" by people in this website by year, and whether "Angiotensinogen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Angiotensinogen" by people in Profiles.
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Chang L, Xiong W, Zhao X, Fan Y, Guo Y, Garcia-Barrio M, Zhang J, Jiang Z, Lin JD, Chen YE. Bmal1 in Perivascular Adipose Tissue Regulates Resting-Phase Blood Pressure Through Transcriptional Regulation of Angiotensinogen. Circulation. 2018 07 03; 138(1):67-79.
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De Mello WC, Dell'Itallia LJ, Varagic J, Ferrario CM. Intracellular angiotensin-(1-12) changes the electrical properties of intact cardiac muscle. Mol Cell Biochem. 2016 Nov; 422(1-2):31-40.
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Sun W, Feng Y, Yao XD, Xu YF, Peng B, Liu M, Zheng JH. Urinary angiotensinogen is elevated in patients with nephrolithiasis. Biomed Res Int. 2014; 2014:349602.
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Yugar-Toledo JC, Martin JF, Krieger JE, Pereira AC, Demacq C, Coelho OR, Pimenta E, Calhoun DA, J?nior HM. Gene variation in resistant hypertension: multilocus analysis of the angiotensin 1-converting enzyme, angiotensinogen, and endothelial nitric oxide synthase genes. DNA Cell Biol. 2011 Aug; 30(8):555-64.
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De Mello WC, Gerena Y. Prolonged exposure of cardiac cells to renin plus angiotensinogen reduces intracellular renin in the failing heart. On the role of angiotensin II-AT1 complex internalization. Regul Pept. 2009 Jun 05; 155(1-3):139-44.
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De Mello WC. Intracellular and extracellular renin have opposite effects on the regulation of heart cell volume. Implications for myocardial ischaemia. J Renin Angiotensin Aldosterone Syst. 2008 Jun; 9(2):112-8.
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Bhuiyan AR, Chen W, Srinivasan SR, Rice J, Mock N, Tang R, Bond MG, Boerwinkle E, Berenson GS. G-6A polymorphism of angiotensinogen gene modulates the effect of blood pressure on carotid intima-media thickness. The Bogalusa Heart Study. Am J Hypertens. 2007 Oct; 20(10):1073-8.
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De Mello WC. Renin increments the inward calcium current in the failing heart. J Hypertens. 2006 Jun; 24(6):1181-6.
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Jones JM, Park JJ, Johnson J, Vizcaino D, Hand B, Ferrell R, Weir M, Dowling T, Obisesan T, Brown M. Renin-angiotensin system genes and exercise training-induced changes in sodium excretion in African American hypertensives. Ethn Dis. 2006; 16(3):666-74.
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Kurdi M, De Mello WC, Booz GW. Working outside the system: an update on the unconventional behavior of the renin-angiotensin system components. Int J Biochem Cell Biol. 2005 Jul; 37(7):1357-67.