Angiotensin II

"Angiotensin II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS.

Descriptor ID	D000804
MeSH Number(s)	D06.472.699.094.078 D12.644.400.070.078 D12.644.456.073.041 D12.644.548.058.078 D12.776.631.650.070.078 D23.469.050.050.050
Concept/Terms	Angiotensin II Angiotensin II ANG-(1-8)Octapeptide Angiotensin-(1-8) Octapeptide Angiotensin II, Val(5)- Angiotensin II, Val(5)- Angiotensin II, Valine(5)- Valyl(5)-Angiotensin II Angiotensin II, Ile(5)- Angiotensin II, Ile(5)- Angiotensin II, Isoleucine(5)- 5-L-Isoleucine Angiotensin II 5 L Isoleucine Angiotensin II Angiotensin II, 5-L-Isoleucine Isoleucine(5)-Angiotensin Isoleucyl(5)-Angiotensin II

Below are MeSH descriptors whose meaning is more general than "Angiotensin II".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Angiotensins [D06.472.699.094]
Angiotensin II [D06.472.699.094.078]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Angiotensins [D12.644.400.070]
Angiotensin II [D12.644.400.070.078]
Oligopeptides [D12.644.456]
Angiotensins [D12.644.456.073]
Angiotensin II [D12.644.456.073.041]
Peptide Hormones [D12.644.548]
Angiotensins [D12.644.548.058]
Angiotensin II [D12.644.548.058.078]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Angiotensins [D12.776.631.650.070]
Angiotensin II [D12.776.631.650.070.078]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Angiotensins [D23.469.050.050]
Angiotensin II [D23.469.050.050.050]

Below are MeSH descriptors whose meaning is related to "Angiotensin II".

Below are MeSH descriptors whose meaning is more specific than "Angiotensin II".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Angiotensin II" by people in this website by year, and whether "Angiotensin II" was a major or minor topic of these publications.

Bar chart showing 79 publications over 28 distinct years, with a maximum of 9 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	0	2
1995	1	0	1
1996	3	0	3
1997	0	2	2
1999	1	1	2
2000	2	0	2
2001	3	0	3
2002	2	1	3
2003	2	3	5
2004	2	1	3
2005	7	2	9
2006	4	2	6
2007	1	2	3
2008	2	0	2
2009	1	1	2
2010	1	2	3
2011	2	1	3
2012	3	4	7
2013	2	1	3
2014	2	0	2
2015	1	1	2
2017	2	1	3
2018	1	0	1
2019	1	0	1
2020	0	1	1
2021	1	0	1
2022	1	1	2
2024	1	1	2

Below are the most recent publications written about "Angiotensin II" by people in Profiles.

Yin Q, Tang TT, Lu XY, Ni WJ, Yin D, Zhang YL, Jiang W, Zhang Y, Li ZL, Wen Y, Gan WH, Zhang AQ, Lv LL, Wang B, Liu BC. Macrophage-derived exosomes promote telomere fragility and senescence in tubular epithelial cells by delivering miR-155. Cell Commun Signal. 2024 Jul 10; 22(1):357.

View in: PubMed
Ni WJ, Li ZL, Wen XL, Ji JL, Liu H, Yin Q, Jiang LY, Zhang YL, Wen Y, Tang TT, Jiang W, Lv LL, Gan WH, Liu BC, Wang B. HIF-1a and adaptor protein LIM and senescent cell antigen-like domains protein 1 axis promotes tubulointerstitial fibrosis by interacting with vimentin in angiotensin II-induced hypertension. Br J Pharmacol. 2024 Sep; 181(17):3098-3117.

View in: PubMed
Kuwabara JT, Hara A, Bhutada S, Gojanovich GS, Chen J, Hokutan K, Shettigar V, Lee AY, DeAngelo LP, Heckl JR, Jahansooz JR, Tacdol DK, Ziolo MT, Apte SS, Tallquist MD. Consequences of PDGFRa+ fibroblast reduction in adult murine hearts. Elife. 2022 09 23; 11.

View in: PubMed
Khundmiri SJ, Ecelbarger CM, Amponsem J, Ji H, Sandberg K, Lee DL. PPAR-a knockout leads to elevated blood pressure response to angiotensin II infusion associated with an increase in renal a-1 Na+/K+ ATPase protein expression and activity. Life Sci. 2022 May 01; 296:120444.

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Collazo BJ, Morales-V?zquez D, ?lvarez-Del Valle J, Sierra-Pagan JE, Medina JC, M?ndez-?lvarez J, Gerena Y. Angiotensin II Induces Differentiation of Human Neuroblastoma Cells by Increasing MAP2 and ROS Levels. J Renin Angiotensin Aldosterone Syst. 2021; 2021:6191417.

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Oyagbemi AA, Bolaji-Alabi FB, Ajibade TO, Adejumobi OA, Ajani OS, Jarikre TA, Omobowale TO, Ola-Davies OE, Soetan KO, Aro AO, Emikpe BO, Saba AB, Adedapo AA, Oyeyemi MO, Nkadimeng SM, Kayoka-Kabongo PN, McGaw LJ, Oguntibeju OO, Yakubu MA. Novel antihypertensive action of rutin is mediated via inhibition of angiotensin converting enzyme/mineralocorticoid receptor/angiotensin 2 type 1 receptor (ATR1) signaling pathways in uninephrectomized hypertensive rats. J Food Biochem. 2020 12; 44(12):e13534.

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Zhao Y, Chang Z, Zhao G, Lu H, Xiong W, Liang W, Wang H, Villacorta L, Garcia-Barrio MT, Zhu T, Guo Y, Fan Y, Chang L, Schopfer FJ, Freeman BA, Zhang J, Chen YE. Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy. Cardiovasc Drugs Ther. 2021 10; 35(5):939-951.

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Lu H, Sun J, Liang W, Chang Z, Rom O, Zhao Y, Zhao G, Xiong W, Wang H, Zhu T, Guo Y, Chang L, Garcia-Barrio MT, Zhang J, Chen YE, Fan Y. Cyclodextrin Prevents Abdominal Aortic Aneurysm via Activation of Vascular Smooth Muscle Cell Transcription Factor EB. Circulation. 2020 08 04; 142(5):483-498.

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Escobales N, Nu?ez RE, Javadov S. Mitochondrial angiotensin receptors and cardioprotective pathways. Am J Physiol Heart Circ Physiol. 2019 06 01; 316(6):H1426-H1438.

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Nu?ez RE, Javadov S, Escobales N. Critical role of angiotensin II type 2 receptors in the control of mitochondrial and cardiac function in angiotensin II-preconditioned rat hearts. Pflugers Arch. 2018 09; 470(9):1391-1403.

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