Extracellular Signal-Regulated MAP Kinases

"Extracellular Signal-Regulated MAP Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.

Descriptor ID	D048049
MeSH Number(s)	D08.811.913.696.620.682.700.567.249 D12.644.360.450.169 D12.776.476.450.169
Concept/Terms	Extracellular Signal-Regulated MAP Kinases Extracellular Signal-Regulated MAP Kinases Extracellular Signal Regulated MAP Kinases MAP Kinases, Extracellular Signal-Regulated MAP Kinases, Extracellular Signal Regulated ERK MAP Kinases Extracellular Signal-Regulated Kinases Extracellular Signal Regulated Kinases Kinases, Extracellular Signal-Regulated

Below are MeSH descriptors whose meaning is more general than "Extracellular Signal-Regulated MAP Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
Mitogen-Activated Protein Kinases [D08.811.913.696.620.682.700.567]
Extracellular Signal-Regulated MAP Kinases [D08.811.913.696.620.682.700.567.249]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Mitogen-Activated Protein Kinases [D12.644.360.450]
Extracellular Signal-Regulated MAP Kinases [D12.644.360.450.169]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Mitogen-Activated Protein Kinases [D12.776.476.450]
Extracellular Signal-Regulated MAP Kinases [D12.776.476.450.169]

Below are MeSH descriptors whose meaning is related to "Extracellular Signal-Regulated MAP Kinases".

Below are MeSH descriptors whose meaning is more specific than "Extracellular Signal-Regulated MAP Kinases".

Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinase 1
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 6
Mitogen-Activated Protein Kinase 7

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Extracellular Signal-Regulated MAP Kinases" by people in this website by year, and whether "Extracellular Signal-Regulated MAP Kinases" was a major or minor topic of these publications.

Bar chart showing 74 publications over 19 distinct years, with a maximum of 8 publications in 2008 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	0	1	1
2005	5	2	7
2006	0	6	6
2007	3	4	7
2008	4	4	8
2009	2	0	2
2010	1	3	4
2011	1	7	8
2012	2	5	7
2013	2	3	5
2014	2	1	3
2015	1	3	4
2016	0	1	1
2017	1	3	4
2018	0	1	1
2019	1	2	3
2021	0	1	1
2022	0	1	1

Below are the most recent publications written about "Extracellular Signal-Regulated MAP Kinases" by people in Profiles.

Umbarkar P, Tousif S, Singh AP, Anderson JC, Zhang Q, Tallquist MD, Woodgett J, Lal H. Fibroblast GSK-3a Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart. Circ Res. 2022 09 16; 131(7):620-636.

View in: PubMed
Vu T, Datta A, Banister C, Jin L, Yuan G, Samuel T, Bae S, Eltoum IE, Manne U, Zhang B, Welner RS, Mitra K, Buckhaults P, Datta PK. Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism. Gastroenterology. 2022 01; 162(1):193-208.

View in: PubMed
S?nchez-Breta?o A, Suen TC, Baba K, DeBruyne J, Tosini G. Melatonin receptor heterodimerization in a photoreceptor-like cell line endogenously expressing melatonin receptors. Mol Vis. 2019; 25:791-799.

View in: PubMed
Li YQ, Ngo A, Hoffmann P, Ferrante A, Hii CS. Regulation of endothelial cell survival and death by the MAP kinase/ERK kinase kinase 3 - glyceraldehyde-3-phosphate dehydrogenase signaling axis. Cell Signal. 2019 06; 58:20-33.

View in: PubMed
Moran H, Cancel LM, Mayer MA, Qazi H, Munn LL, Tarbell JM. The cancer cell glycocalyx proteoglycan Glypican-1 mediates interstitial flow mechanotransduction to enhance cell migration and metastasis. Biorheology. 2019; 56(2-3):151-161.

View in: PubMed
Ruiz-Medina BE, Cadena-Medina DA, Esparza E, Arrieta AJ, Kirken RA. Isoproterenol-induced beta-2 adrenergic receptor activation negatively regulates interleukin-2 signaling. Biochem J. 2018 09 18; 475(18):2907-2923.

View in: PubMed
Yao X, Gray S, Pham T, Delgardo M, Nguyen A, Do S, Ireland SK, Chen R, Abdel-Mageed AB, Biliran H. Downregulation of Bit1 expression promotes growth, anoikis resistance, and transformation of immortalized human bronchial epithelial cells via Erk activation-dependent suppression of E-cadherin. Biochem Biophys Res Commun. 2018 01 01; 495(1):1240-1248.

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Ma CH, Wu CH, Jou IM, Tu YK, Hung CH, Hsieh PL, Tsai KL. PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes. Redox Biol. 2018 04; 14:72-81.

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Karki P, Hong P, Johnson J, Pajarillo E, Son DS, Aschner M, Lee EY. Arundic Acid Increases Expression and Function of Astrocytic Glutamate Transporter EAAT1 Via the ERK, Akt, and NF-?B Pathways. Mol Neurobiol. 2018 Jun; 55(6):5031-5046.

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Yamada T, Kerever A, Yoshimura Y, Suzuki Y, Nonaka R, Higashi K, Toida T, Mercier F, Arikawa-Hirasawa E. Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor-2 signaling impairment in the aged neurogenic niche. J Neurochem. 2017 08; 142(4):534-544.

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