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Hector Biliran

TitleFaculty, Department of Biology
Faculty RankAssociate Professor
InstitutionXavier University of Louisiana
DepartmentBiology
AddressXavier University of Louisiana
1 Drexel Drive
Biology
New Orleans LA 70125
Phone5045207622
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    Collapse Research 
    Collapse research activities and funding
    SC2CA153382     (BILIRAN, HECTOR RAMOS)May 1, 2010 - Apr 30, 2013
    NIH
    Regulation of anoikis and transformation in human breast cancer cells by Bit1
    Role: Principal Investigator
    R15CA158677     (BILIRAN, HECTOR RAMOS)Feb 28, 2012 - Jul 31, 2019
    NIH
    Bit1 as a tumor suppressor and a therapeutic target in NSCLC
    Role: Principal Investigator
    R16GM145484     (BILIRAN, HECTOR RAMOS)Jun 1, 2022 - Apr 30, 2026
    NIH
    Role of the transcriptional corepressor TLE1 in the lung adenocarcinoma aggressiveness and progression
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yao X, Gray S, Pham T, Delgardo M, Nguyen A, Do S, Ireland SK, Chen R, Abdel-Mageed AB, Biliran H. Downregulation of Bit1 expression promotes growth, anoikis resistance, and transformation of immortalized human bronchial epithelial cells via Erk activation-dependent suppression of E-cadherin. Biochem Biophys Res Commun. 2018 01 01; 495(1):1240-1248. PMID: 29170133.
      Citations: 7     Fields:    Translation:HumansCells
    2. Yao X, Pham T, Temple B, Gray S, Cannon C, Hardy C, Fletcher K, Ireland SK, Hossain A, Chen R, Abdel-Mageed AB, Biliran H. TLE1 inhibits anoikis and promotes tumorigenicity in human lung cancer cells through ZEB1-mediated E-cadherin repression. Oncotarget. 2017 Sep 22; 8(42):72235-72249. PMID: 29069783.
      Citations: 9     Fields:    
    3. Yao X, Pham T, Temple B, Gray S, Cannon C, Chen R, Abdel-Mageed AB, Biliran H. The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells. PLoS One. 2016; 11(9):e0163228. PMID: 27655370.
      Citations: 10     Fields:    Translation:HumansCells
    4. Yao X, Ireland SK, Pham T, Temple B, Chen R, Raj MH, Biliran H. TLE1 promotes EMT in A549 lung cancer cells through suppression of E-cadherin. Biochem Biophys Res Commun. 2014 Dec 12; 455(3-4):277-84. PMID: 25446087.
      Citations: 25     Fields:    Translation:HumansCells
    5. Yao X, Jennings S, Ireland SK, Pham T, Temple B, Davis M, Chen R, Davenport I, Biliran H. The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells. PLoS One. 2014; 9(7):e101564. PMID: 25003198.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    6. Jenning S, Pham T, Ireland SK, Ruoslahti E, Biliran H. Bit1 in anoikis resistance and tumor metastasis. Cancer Lett. 2013 Jun 10; 333(2):147-51. PMID: 23376255.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    7. Brunquell C, Biliran H, Jennings S, Ireland SK, Chen R, Ruoslahti E. TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells. Mol Cancer Res. 2012 Nov; 10(11):1482-95. PMID: 22952044.
      Citations: 26     Fields:    Translation:HumansCells
    8. Karmali PP, Brunquell C, Tram H, Ireland SK, Ruoslahti E, Biliran H. Metastasis of tumor cells is enhanced by downregulation of Bit1. PLoS One. 2011; 6(8):e23840. PMID: 21886829.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    9. Biliran H, Jan Y, Chen R, Pasquale EB, Ruoslahti E. Protein kinase D is a positive regulator of Bit1 apoptotic function. J Biol Chem. 2008 Oct 17; 283(42):28029-37. PMID: 18703509.
      Citations: 21     Fields:    Translation:HumansCells
    10. Thakur A, Sun Y, Bollig A, Wu J, Biliran H, Banerjee S, Sarkar FH, Liao DJ. Anti-invasive and antimetastatic activities of ribosomal protein S6 kinase 4 in breast cancer cells. Clin Cancer Res. 2008 Jul 15; 14(14):4427-36. PMID: 18628456.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    11. Kairouz-Wahbe R, Biliran H, Luo X, Khor I, Wankell M, Besch-Williford C, Pascual J, Oshima R, Ruoslahti E. Anoikis effector Bit1 negatively regulates Erk activity. Proc Natl Acad Sci U S A. 2008 Feb 05; 105(5):1528-32. PMID: 18218778.
      Citations: 22     Fields:    Translation:AnimalsCells
    12. Liao DJ, Thakur A, Wu J, Biliran H, Sarkar FH. Perspectives on c-Myc, Cyclin D1, and their interaction in cancer formation, progression, and response to chemotherapy. Crit Rev Oncog. 2007 Nov; 13(2):93-158. PMID: 18197790.
      Citations: 61     Fields:    Translation:Humans
    13. Biliran H, Banerjee S, Thakur A, Sarkar FH, Bollig A, Ahmed F, Wu J, Sun Y, Liao JD. c-Myc-induced chemosensitization is mediated by suppression of cyclin D1 expression and nuclear factor-kappa B activity in pancreatic cancer cells. Clin Cancer Res. 2007 May 01; 13(9):2811-21. PMID: 17473215.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    14. Wang Y, Thakur A, Sun Y, Wu J, Biliran H, Bollig A, Liao DJ. Synergistic effect of cyclin D1 and c-Myc leads to more aggressive and invasive mammary tumors in severe combined immunodeficient mice. Cancer Res. 2007 Apr 15; 67(8):3698-707. PMID: 17440082.
      Citations: 18     Fields:    Translation:AnimalsCells
    15. Thakur A, Rahman KW, Wu J, Bollig A, Biliran H, Lin X, Nassar H, Grignon DJ, Sarkar FH, Liao JD. Aberrant expression of X-linked genes RbAp46, Rsk4, and Cldn2 in breast cancer. Mol Cancer Res. 2007 Feb; 5(2):171-81. PMID: 17314274.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    16. Yin S, Lockett J, Meng Y, Biliran H, Blouse GE, Li X, Reddy N, Zhao Z, Lin X, Anagli J, Cher ML, Sheng S. Maspin retards cell detachment via a novel interaction with the urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor system. Cancer Res. 2006 Apr 15; 66(8):4173-81. PMID: 16618739.
      Citations: 29     Fields:    Translation:HumansCells
    17. Thakur A, Xu H, Wang Y, Bollig A, Biliran H, Liao JD. The role of X-linked genes in breast cancer. Breast Cancer Res Treat. 2005 Sep; 93(2):135-43. PMID: 16187233.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    18. Biliran H, Wang Y, Banerjee S, Xu H, Heng H, Thakur A, Bollig A, Sarkar FH, Liao JD. Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line. Clin Cancer Res. 2005 Aug 15; 11(16):6075-86. PMID: 16115953.
      Citations: 84     Fields:    Translation:AnimalsCells
    19. Laakkonen P, Akerman ME, Biliran H, Yang M, Ferrer F, Karpanen T, Hoffman RM, Ruoslahti E. Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. Proc Natl Acad Sci U S A. 2004 Jun 22; 101(25):9381-6. PMID: 15197262.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    20. Cher ML, Biliran HR, Bhagat S, Meng Y, Che M, Lockett J, Abrams J, Fridman R, Zachareas M, Sheng S. Maspin expression inhibits osteolysis, tumor growth, and angiogenesis in a model of prostate cancer bone metastasis. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7847-52. PMID: 12788977.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
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