Co-Repressor Proteins

"Co-Repressor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of repressor proteins that do not directly bind DNA. Instead, co-repressors generally act via their interaction with DNA-BINDING PROTEINS such as a TRANSCRIPTIONAL SILENCING FACTORS or NUCLEAR RECEPTORS.

Descriptor ID	D056970
MeSH Number(s)	D12.776.930.780.625
Concept/Terms	Co-Repressor Proteins Co-Repressor Proteins Co Repressor Proteins Corepressor Proteins Corepressors Co-Repressors Co Repressors Nuclear Receptor Co-Repressors Nuclear Receptor Co-Repressors Co-Repressors, Nuclear Receptor Nuclear Receptor Co Repressors Receptor Co-Repressors, Nuclear Nuclear Receptor Corepressors Corepressors, Nuclear Receptor Nuclear Hormone Receptor Co-Repressors Nuclear Hormone Receptor Co-Repressors Nuclear Hormone Receptor Co Repressors

Below are MeSH descriptors whose meaning is more general than "Co-Repressor Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Repressor Proteins [D12.776.930.780]
Co-Repressor Proteins [D12.776.930.780.625]

Below are MeSH descriptors whose meaning is related to "Co-Repressor Proteins".

Below are MeSH descriptors whose meaning is more specific than "Co-Repressor Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Co-Repressor Proteins" by people in this website by year, and whether "Co-Repressor Proteins" was a major or minor topic of these publications.

Bar chart showing 15 publications over 10 distinct years, with a maximum of 3 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	2	2
2007	0	1	1
2008	0	1	1
2009	0	1	1
2011	1	1	2
2012	0	1	1
2013	0	1	1
2014	1	2	3
2016	0	2	2
2025	1	0	1

Below are the most recent publications written about "Co-Repressor Proteins" by people in Profiles.

Dela Cruz MC, Yao X, Roberts N, Iheukwumere P, Carmouche A, Medina PM, Biliran H. TLE1 drives EGFR-TKI resistance in EGFR-mutant lung adenocarcinoma through epithelial to mesenchymal transition. Biochem Biophys Res Commun. 2025 Aug 15; 775:152146.

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Benitez JA, Ma J, D'Antonio M, Boyer A, Camargo MF, Zanca C, Kelly S, Khodadadi-Jamayran A, Jameson NM, Andersen M, Miletic H, Saberi S, Frazer KA, Cavenee WK, Furnari FB. PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. Nat Commun. 2017 05 12; 8:15223.

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Yao X, Pham T, Temple B, Gray S, Cannon C, Chen R, Abdel-Mageed AB, Biliran H. The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells. PLoS One. 2016; 11(9):e0163228.

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Saha TT, Shin SW, Dou W, Roy S, Zhao B, Hou Y, Wang XL, Zou Z, Girke T, Raikhel AS. Hairy and Groucho mediate the action of juvenile hormone receptor Methoprene-tolerant in gene repression. Proc Natl Acad Sci U S A. 2016 Feb 09; 113(6):E735-43.

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Yao X, Ireland SK, Pham T, Temple B, Chen R, Raj MH, Biliran H. TLE1 promotes EMT in A549 lung cancer cells through suppression of E-cadherin. Biochem Biophys Res Commun. 2014 Dec 12; 455(3-4):277-84.

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Yao X, Jennings S, Ireland SK, Pham T, Temple B, Davis M, Chen R, Davenport I, Biliran H. The anoikis effector Bit1 displays tumor suppressive function in lung cancer cells. PLoS One. 2014; 9(7):e101564.

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Upadhyay G, Chowdhury AH, Vaidyanathan B, Kim D, Saleque S. Antagonistic actions of Rcor proteins regulate LSD1 activity and cellular differentiation. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8071-6.

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Chowdhury AH, Ramroop JR, Upadhyay G, Sengupta A, Andrzejczyk A, Saleque S. Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST. PLoS One. 2013; 8(1):e53666.

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Brunquell C, Biliran H, Jennings S, Ireland SK, Chen R, Ruoslahti E. TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells. Mol Cancer Res. 2012 Nov; 10(11):1482-95.

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Castle CD, Cassimere EK, Denicourt C. LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis. Mol Biol Cell. 2012 Feb; 23(4):716-28.

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