Estrogen Receptor alpha

"Estrogen Receptor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

One of the ESTROGEN RECEPTORS that has marked affinity for ESTRADIOL. Its expression and function differs from, and in some ways opposes, ESTROGEN RECEPTOR BETA.

Descriptor ID	D047628
MeSH Number(s)	D12.776.826.750.350.174
Concept/Terms	Estrogen Receptor alpha Estrogen Receptor alpha Estradiol Receptor alpha Receptor alpha, Estradiol alpha, Estradiol Receptor Receptor alpha, Estrogen ERalpha Estrogen Receptors alpha Estrogen Receptor 1 Estrogen Receptor 1

Below are MeSH descriptors whose meaning is more general than "Estrogen Receptor alpha".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]
Receptors, Steroid [D12.776.826.750]
Receptors, Estrogen [D12.776.826.750.350]
Estrogen Receptor alpha [D12.776.826.750.350.174]

Below are MeSH descriptors whose meaning is related to "Estrogen Receptor alpha".

Below are MeSH descriptors whose meaning is more specific than "Estrogen Receptor alpha".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Estrogen Receptor alpha" by people in this website by year, and whether "Estrogen Receptor alpha" was a major or minor topic of these publications.

Bar chart showing 76 publications over 22 distinct years, with a maximum of 8 publications in 2009 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	1	1
2001	0	1	1
2003	0	4	4
2004	0	2	2
2005	1	2	3
2006	0	2	2
2007	1	2	3
2008	2	1	3
2009	3	5	8
2010	2	3	5
2011	2	4	6
2012	3	1	4
2013	2	2	4
2014	1	3	4
2015	4	4	8
2016	2	2	4
2017	0	3	3
2019	5	1	6
2020	1	1	2
2021	0	1	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Estrogen Receptor alpha" by people in Profiles.

Abdulkareem AO, Tiwari P, Lone ZR, Iqbal H, Gupta S, Jha RK, Chanda D, Jagavelu K, Hanif K. Ormeloxifene, a selective estrogen receptor modulator, protects against pulmonary hypertension. Eur J Pharmacol. 2023 Mar 15; 943:175558.

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Debnath S, Lu X, Lal A, Sharma S. Genome-wide investigations on regulatory functions of RECQ1 helicase. Methods. 2022 08; 204:263-268.

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Lu X, Redon CE, Tang W, Parvathaneni S, Bokhari B, Debnath S, Li XL, Muys BR, Song Y, Pongor LS, Sheikh O, Green AR, Madhusudan S, Lal A, Ambs S, Khan J, Aladjem MI, Sharma S. Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells. Mol Cell Biol. 2021 03 24; 41(4).

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Ma Z, Parris AB, Howard EW, Davis M, Cao X, Woods C, Yang X. In Utero Exposure to Bisphenol a Promotes Mammary Tumor Risk in MMTV-Erbb2 Transgenic Mice Through the Induction of ER-erbB2 Crosstalk. Int J Mol Sci. 2020 Apr 28; 21(9).

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Guo S, Zhang C, Mottamal M, Hossain A, Liu J, Wang G. GLL398, an oral selective estrogen receptor degrader (SERD), blocks tumor growth in xenograft breast cancer models. Breast Cancer Res Treat. 2020 Apr; 180(2):359-368.

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Col?n-Caraballo M, Garc?a M, Mendoza A, Flores I. Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67. Appl Immunohistochem Mol Morphol. 2019 08; 27(7):491-500.

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Chitrala KN, Nagarkatti M, Nagarkatti P, Yeguvapalli S. Analysis of the TP53 Deleterious Single Nucleotide Polymorphisms Impact on Estrogen Receptor Alpha-p53 Interaction: A Machine Learning Approach. Int J Mol Sci. 2019 Jun 18; 20(12).

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Zhao Q, Howard EW, Parris AB, Ma Z, Xing Y, Yang X. Bisphenol AF promotes estrogen receptor-positive breast cancer cell proliferation through amphiregulin-mediated crosstalk with receptor tyrosine kinase signaling. PLoS One. 2019; 14(5):e0216469.

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Burton LJ, Hawsawi O, Sweeney J, Bowen N, Hudson T, Odero-Marah V. CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-a) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE). PLoS One. 2019; 14(4):e0214844.

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Wang Z, Katsaros D, Biglia N, Shen Y, Loo L, Yu X, Lin H, Fu Y, Chu WM, Fei P, Ni Y, Jia W, Deng X, Qian B, Yu H. ERa upregulates the expression of long non-coding RNA LINC00472 which suppresses the phosphorylation of NF-?B in breast cancer. Breast Cancer Res Treat. 2019 Jun; 175(2):353-368.

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