"Pertussis Toxin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.
Descriptor ID |
D037342
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MeSH Number(s) |
D08.811.913.400.725.115.680 D23.946.123.946.690 D23.946.896.980.690
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Concept/Terms |
Pertussis Toxin- Pertussis Toxin
- Toxin, Pertussis
- Lymphocytosis-Promoting Factor
- Lymphocytosis Promoting Factor
- Islet-Activating Protein
- Islet Activating Protein
- Histamine-Sensitizing Factor
- Histamine Sensitizing Factor
- IAP Pertussis Toxin
- Pertussis Toxin, IAP
- Toxin, IAP Pertussis
- Islets-Activating Protein
- Islets Activating Protein
- Pertussigen
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Below are MeSH descriptors whose meaning is more general than "Pertussis Toxin".
Below are MeSH descriptors whose meaning is more specific than "Pertussis Toxin".
This graph shows the total number of publications written about "Pertussis Toxin" by people in this website by year, and whether "Pertussis Toxin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 0 | 1 | 1 |
2000 | 1 | 0 | 1 |
2002 | 1 | 1 | 2 |
2003 | 0 | 3 | 3 |
2006 | 0 | 1 | 1 |
2007 | 2 | 3 | 5 |
2010 | 2 | 1 | 3 |
2011 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pertussis Toxin" by people in Profiles.
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Sesay JS, Gyapong RN, Najafi LT, Kabler SL, Diz DI, Howlett AC, Awumey EM. Gai/o-dependent Ca(2+) mobilization and Gaq-dependent PKCa regulation of Ca(2+)-sensing receptor-mediated responses in N18TG2 neuroblastoma cells. Neurochem Int. 2015 Nov; 90:142-51.
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Turvey ME, Koudelka T, Comerford I, Greer JM, Carroll W, Bernard CC, Hoffmann P, McColl SR. Quantitative proteome profiling of CNS-infiltrating autoreactive CD4+ cells reveals selective changes during experimental autoimmune encephalomyelitis. J Proteome Res. 2014 Aug 01; 13(8):3655-70.
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Sosa RA, Murphey C, Ji N, Cardona AE, Forsthuber TG. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15; 191(12):5848-57.
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Ji N, Rao N, Guentzel NM, Arulanandam BP, Forsthuber TG. Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin. J Immunol. 2011 Mar 01; 186(5):2750-6.
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Murphey C, Chang S, Zhang X, Arulanandam B, Forsthuber TG. Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin. Cell Immunol. 2011; 267(1):50-5.
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Zhong M, Boseman ML, Millena AC, Khan SA. Oxytocin induces the migration of prostate cancer cells: involvement of the Gi-coupled signaling pathway. Mol Cancer Res. 2010 Aug; 8(8):1164-72.
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Hofstetter HH, Forsthuber TG. Kinetics of IL-17- and interferon-gamma-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice. Neurosci Lett. 2010 Jun 07; 476(3):150-5.
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Hofstetter HH, Grau C, Buttmann M, Forsthuber TG, Gaupp S, Toyka KV, Gold R. The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells. Cytokine. 2007 Oct; 40(1):35-43.
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Jones JD, Carney ST, Vrana KE, Norford DC, Howlett AC. Cannabinoid receptor-mediated translocation of NO-sensitive guanylyl cyclase and production of cyclic GMP in neuronal cells. Neuropharmacology. 2008 Jan; 54(1):23-30.
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Denkinger CM, Denkinger MD, Forsthuber TG. Pertussis toxin-induced cytokine differentiation and clonal expansion of T cells is mediated predominantly via costimulation. Cell Immunol. 2007 Mar; 246(1):46-54.