Virulence Factors

"Virulence Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)

Descriptor ID	D037521
MeSH Number(s)	D23.946.896
Concept/Terms	Virulence Factors Virulence Factors Factors, Virulence Pathogenicity Factors Factors, Pathogenicity

Below are MeSH descriptors whose meaning is more general than "Virulence Factors".

Chemicals and Drugs [D]
Biological Factors [D23]
Toxins, Biological [D23.946]
Virulence Factors [D23.946.896]

Below are MeSH descriptors whose meaning is related to "Virulence Factors".

Below are MeSH descriptors whose meaning is more specific than "Virulence Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Virulence Factors" by people in this website by year, and whether "Virulence Factors" was a major or minor topic of these publications.

Bar chart showing 84 publications over 19 distinct years, with a maximum of 9 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	0	1	1
2005	3	0	3
2006	0	3	3
2007	2	3	5
2008	3	2	5
2009	7	1	8
2010	2	0	2
2011	2	1	3
2012	3	3	6
2013	6	3	9
2014	4	1	5
2015	4	1	5
2016	2	2	4
2017	0	6	6
2018	3	1	4
2019	2	3	5
2020	0	4	4
2021	2	3	5
2022	0	1	1

Below are the most recent publications written about "Virulence Factors" by people in Profiles.

Grajeda BI, De Chatterjee A, Villalobos CM, Pence BC, Ellis CC, Enriquez V, Roy S, Roychowdhury S, Neumann AK, Almeida IC, Patterson SE, Das S. Giardial lipid rafts share virulence factors with secreted vesicles and participate in parasitic infection in mice. Front Cell Infect Microbiol. 2022; 12:974200.

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Bao Y, Wang L, Sun J. Post-translational knockdown and post-secretional modification of EsxA determine contribution of EsxA membrane permeabilizing activity for mycobacterial intracellular survival. Virulence. 2021 12; 12(1):312-328.

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Shrihari S, May HC, Yu JJ, Papp SB, Chambers JP, Guentzel MN, Arulanandam BP. Thioredoxin-mediated alteration of protein content and cytotoxicity of Acinetobacter baumannii outer membrane vesicles. Exp Biol Med (Maywood). 2022 02; 247(3):282-288.

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McMillan IA, Norris MH, Zarzycki-Siek J, Heacock-Kang Y, Sun Z, Borlee BR, Hoang TT. Identification of a PadR-type regulator essential for intracellular pathogenesis of Burkholderia pseudomallei. Sci Rep. 2021 05 17; 11(1):10405.

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Dow A, Sule P, O'Donnell TJ, Burger A, Mattila JT, Antonio B, Vergara K, Marcantonio E, Adams LG, James N, Williams PG, Cirillo JD, Prisic S. Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosis. PLoS Pathog. 2021 05; 17(5):e1009570.

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Heacock-Kang Y, McMillan IA, Norris MH, Sun Z, Zarzycki-Siek J, Bluhm AP, Cabanas D, Norton RE, Ketheesan N, Miller JF, Schweizer HP, Hoang TT. The Burkholderia pseudomallei intracellular 'TRANSITome'. Nat Commun. 2021 03 26; 12(1):1907.

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Bennett BD, Essock-Burns T, Ruby EG. HbtR, a Heterofunctional Homolog of the Virulence Regulator TcpP, Facilitates the Transition between Symbiotic and Planktonic Lifestyles in Vibrio fischeri. mBio. 2020 09 01; 11(5).

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Zuo X, Wang L, Bao Y, Sun J. The ESX-1 Virulence Factors Downregulate miR-147-3p in Mycobacterium marinum-Infected Macrophages. Infect Immun. 2020 05 20; 88(6).

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Bottomley AL, Peterson E, Iosifidis G, Yong AMH, Hartley-Tassell LE, Ansari S, McKenzie C, Burke C, Duggin IG, Kline KA, Harry EJ. The novel E. coli cell division protein, YtfB, plays a role in eukaryotic cell adhesion. Sci Rep. 2020 04 21; 10(1):6745.

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Aguilera J, Karki CB, Li L, Vazquez Reyes S, Estevao I, Grajeda BI, Zhang Q, Arico CD, Ouellet H, Sun J. Na-Acetylation of the virulence factor EsxA is required for mycobacterial cytosolic translocation and virulence. J Biol Chem. 2020 04 24; 295(17):5785-5794.

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