mRNA Cleavage and Polyadenylation Factors

"mRNA Cleavage and Polyadenylation Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Factors that are involved in directing the cleavage and POLYADENYLATION of the of MESSENGER RNA near the site of the RNA 3' POLYADENYLATION SIGNALS.

Descriptor ID	D039221
MeSH Number(s)	D12.776.157.725.124 D12.776.664.962.444
Concept/Terms	mRNA Cleavage and Polyadenylation Factors mRNA Cleavage and Polyadenylation Factors Cleavage and Polyadenylation Factors Cleavage and Polyadenylation Factor Polyadenylation Factors Polyadenylation Factors Pre-mRNA Polyadenylation Factor Polyadenylation Factor, Pre-mRNA Pre mRNA Polyadenylation Factor Polyadenylation Factor

Below are MeSH descriptors whose meaning is more general than "mRNA Cleavage and Polyadenylation Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
RNA-Binding Proteins [D12.776.157.725]
mRNA Cleavage and Polyadenylation Factors [D12.776.157.725.124]
Nucleoproteins [D12.776.664]
RNA-Binding Proteins [D12.776.664.962]
mRNA Cleavage and Polyadenylation Factors [D12.776.664.962.444]

Below are MeSH descriptors whose meaning is related to "mRNA Cleavage and Polyadenylation Factors".

Below are MeSH descriptors whose meaning is more specific than "mRNA Cleavage and Polyadenylation Factors".

mRNA Cleavage and Polyadenylation Factors
Cleavage And Polyadenylation Specificity Factor
Cleavage Stimulation Factor

publications

Timeline | Most Recent

This graph shows the total number of publications written about "mRNA Cleavage and Polyadenylation Factors" by people in this website by year, and whether "mRNA Cleavage and Polyadenylation Factors" was a major or minor topic of these publications.

Bar chart showing 17 publications over 13 distinct years, with a maximum of 5 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2001	0	1	1
2006	0	1	1
2008	4	1	5
2010	1	0	1
2011	1	0	1
2012	1	0	1
2013	1	0	1
2016	1	0	1
2018	0	1	1
2019	1	0	1
2020	1	0	1
2025	1	0	1

Below are the most recent publications written about "mRNA Cleavage and Polyadenylation Factors" by people in Profiles.

Chaudhuri E, Jang S, Chakraborty R, Radhakrishnan R, Arnarson B, Prakash P, Cornish D, Rohlfes N, Singh PK, Shi J, Aiken C, Campbell E, Hultquist J, Balsubramaniam M, Engelman AN, Dash C. CPSF6 promotes HIV-1 preintegration complex function. J Virol. 2025 May 20; 99(5):e0049025.

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Chaudhuri E, Dash S, Balasubramaniam M, Padron A, Holland J, Sowd GA, Villalta F, Engelman AN, Pandhare J, Dash C. The HIV-1 capsid-binding host factor CPSF6 is post-transcriptionally regulated by the cellular microRNA miR-125b. J Biol Chem. 2020 04 10; 295(15):5081-5094.

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Yu Z, Lin J, Li QQ. Transcriptome Analyses of FY Mutants Reveal Its Role in mRNA Alternative Polyadenylation. Plant Cell. 2019 10; 31(10):2332-2352.

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Fonseca D, Baquero J, Murphy MR, Aruggoda G, Varriano S, Sapienza C, Mashadova O, Rahman S, Kleiman FE. mRNA Processing Factor CstF-50 and Ubiquitin Escort Factor p97 Are BRCA1/BARD1 Cofactors Involved in Chromatin Remodeling during the DNA Damage Response. Mol Cell Biol. 2018 02 15; 38(4).

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Khleborodova A, Pan X, Nagre NN, Ryan K. An investigation into the role of ATP in the mammalian pre-mRNA 3' cleavage reaction. Biochimie. 2016 Jun; 125:213-22.

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Jaworski C, Looi JL, Martin J, Bergin P, Hare J, Kaye D, Wei A, Taylor AJ. Cardiac Imaging in FIP1L1-PDGFRA. J Am Coll Cardiol. 2013 Oct 01; 62(14):1304.

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Hunt AG, Xing D, Li QQ. Plant polyadenylation factors: conservation and variety in the polyadenylation complex in plants. BMC Genomics. 2012 Nov 20; 13:641.

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Zheng J, Xing D, Wu X, Shen Y, Kroll DM, Ji G, Li QQ. Ratio-based analysis of differential mRNA processing and expression of a polyadenylation factor mutant pcfs4 using arabidopsis tiling microarray. PLoS One. 2011 Feb 25; 6(2):e14719.

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Cevher MA, Zhang X, Fernandez S, Kim S, Baquero J, Nilsson P, Lee S, Virtanen A, Kleiman FE. Nuclear deadenylation/polyadenylation factors regulate 3' processing in response to DNA damage. EMBO J. 2010 May 19; 29(10):1674-87.

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Xing D, Zhao H, Li QQ. Arabidopsis CLP1-SIMILAR PROTEIN3, an ortholog of human polyadenylation factor CLP1, functions in gametophyte, embryo, and postembryonic development. Plant Physiol. 2008 Dec; 148(4):2059-69.

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