Tamoxifen

"Tamoxifen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the ENDOMETRIUM.

Descriptor ID	D013629
MeSH Number(s)	D02.455.426.559.389.150.700.900
Concept/Terms	Tamoxifen Tamoxifen ICI-47699 ICI-47699 ICI 47699 ICI47699 Nolvadex Nolvadex Novaldex Tamoxifen Citrate Tamoxifen Citrate Citrate, Tamoxifen Tomaxithen Tomaxithen Zitazonium Zitazonium ICI-46474 ICI-46474 ICI 46474 ICI46474 ICI-46,474 ICI 46,474 ICI46,474 Soltamox Soltamox

Below are MeSH descriptors whose meaning is more general than "Tamoxifen".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Hydrocarbons [D02.455]
Hydrocarbons, Cyclic [D02.455.426]
Hydrocarbons, Aromatic [D02.455.426.559]
Benzene Derivatives [D02.455.426.559.389]
Benzylidene Compounds [D02.455.426.559.389.150]
Stilbenes [D02.455.426.559.389.150.700]
Tamoxifen [D02.455.426.559.389.150.700.900]

Below are MeSH descriptors whose meaning is related to "Tamoxifen".

Below are MeSH descriptors whose meaning is more specific than "Tamoxifen".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tamoxifen" by people in this website by year, and whether "Tamoxifen" was a major or minor topic of these publications.

Bar chart showing 42 publications over 20 distinct years, with a maximum of 4 publications in 2015 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1996	0	1	1
2003	2	0	2
2005	1	1	2
2006	1	1	2
2007	1	1	2
2008	1	0	1
2009	0	1	1
2010	0	3	3
2011	2	1	3
2012	1	2	3
2013	2	0	2
2014	1	0	1
2015	2	2	4
2016	2	2	4
2017	3	0	3
2018	0	2	2
2019	1	1	2
2020	2	0	2
2022	0	1	1

Below are the most recent publications written about "Tamoxifen" by people in Profiles.

Umbarkar P, Tousif S, Singh AP, Anderson JC, Zhang Q, Tallquist MD, Woodgett J, Lal H. Fibroblast GSK-3a Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart. Circ Res. 2022 09 16; 131(7):620-636.

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Robinson AGJ, Kanaan YM, Copeland RL. Combinatorial Cytotoxic Effects of 2,3-Dichloro-5,8-dimethoxy-1,4-naphthoquinone and 4-hydroxytamoxifen in Triple-negative Breast Cancer Cell Lines. Anticancer Res. 2020 Dec; 40(12):6623-6635.

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Edelman AB, Kaneshiro B, Simmons KB, Hauschildt JL, Bond K, Boniface ER, Jensen JT. Treatment of Unfavorable Bleeding Patterns in Contraceptive Implant Users: A Randomized Controlled Trial. Obstet Gynecol. 2020 08; 136(2):323-332.

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Wang Z, Katsaros D, Biglia N, Shen Y, Loo L, Yu X, Lin H, Fu Y, Chu WM, Fei P, Ni Y, Jia W, Deng X, Qian B, Yu H. ERa upregulates the expression of long non-coding RNA LINC00472 which suppresses the phosphorylation of NF-?B in breast cancer. Breast Cancer Res Treat. 2019 Jun; 175(2):353-368.

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Korecki AJ, Hickmott JW, Lam SL, Dreolini L, Mathelier A, Baker O, Kuehne C, Bonaguro RJ, Smith J, Tan CV, Zhou M, Goldowitz D, Deussing JM, Stewart AF, Wasserman WW, Holt RA, Simpson EM. Twenty-Seven Tamoxifen-Inducible iCre-Driver Mouse Strains for Eye and Brain, Including Seventeen Carrying a New Inducible-First Constitutive-Ready Allele. Genetics. 2019 04; 211(4):1155-1177.

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Campbell PS, Mavingire N, Khan S, Rowland LK, Wooten JV, Opoku-Agyeman A, Guevara A, Soto U, Cavalli F, Loaiza-P?rez AI, Nagaraj G, Denham LJ, Adeoye O, Jenkins BD, Davis MB, Schiff R, Brantley EJ. AhR ligand aminoflavone suppresses a6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells. J Cell Physiol. 2018 01; 234(1):108-121.

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Ding J, Stopeck AT, Gao Y, Marron MT, Wertheim BC, Altbach MI, Galons JP, Roe DJ, Wang F, Maskarinec G, Thomson CA, Thompson PA, Huang C. Reproducible automated breast density measure with no ionizing radiation using fat-water decomposition MRI. J Magn Reson Imaging. 2018 10; 48(4):971-981.

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Pajarillo E, Johnson J, Kim J, Karki P, Son DS, Aschner M, Lee E. 17?-estradiol and tamoxifen protect mice from manganese-induced dopaminergic neurotoxicity. Neurotoxicology. 2018 03; 65:280-288.

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Col?n JM, Gonz?lez PA, Cajigas ?, Maldonado WI, Torrado AI, Santiago JM, Salgado IK, Miranda JD. Continuous tamoxifen delivery improves locomotor recovery 6h after spinal cord injury by neuronal and glial mechanisms in male rats. Exp Neurol. 2018 01; 299(Pt A):109-121.

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Thomson CA, Chow HHS, Wertheim BC, Roe DJ, Stopeck A, Maskarinec G, Altbach M, Chalasani P, Huang C, Strom MB, Galons JP, Thompson PA. A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen. Breast Cancer Res Treat. 2017 Aug; 165(1):97-107.

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