"Leydig Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Steroid-producing cells in the interstitial tissue of the TESTIS. They are under the regulation of PITUITARY HORMONES; LUTEINIZING HORMONE; or interstitial cell-stimulating hormone. TESTOSTERONE is the major androgen (ANDROGENS) produced.
| Descriptor ID |
D007985
|
| MeSH Number(s) |
A05.360.444.849.513 A06.407.312.782.513 A11.382.906 A11.436.513
|
| Concept/Terms |
Leydig Cells- Leydig Cells
- Cells, Leydig
- Testicular Interstitial Cells
- Interstitial Cells, Testicular
- Cell, Testicular Interstitial
- Cells, Testicular Interstitial
- Interstitial Cell, Testicular
- Testicular Interstitial Cell
|
Below are MeSH descriptors whose meaning is more general than "Leydig Cells".
Below are MeSH descriptors whose meaning is more specific than "Leydig Cells".
This graph shows the total number of publications written about "Leydig Cells" by people in this website by year, and whether "Leydig Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Leydig Cells" by people in Profiles.
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Shen YC, Shami AN, Moritz L, Larose H, Manske GL, Ma Q, Zheng X, Sukhwani M, Czerwinski M, Sultan C, Chen H, Gurczynski SJ, Spence JR, Orwig KE, Tallquist M, Li JZ, Hammoud SS. TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice. Nat Commun. 2021 06 23; 12(1):3876.
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Wu JJ, Wang KL, Wang SW, Hwang GS, Mao IF, Chen ML, Wang PS. Differential effects of nonylphenol on testosterone secretion in rat Leydig cells. Toxicology. 2010 Jan 31; 268(1-2):1-7.
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Singh KP, Kumari R, Pevey C, Jackson D, DuMond JW. Long duration exposure to cadmium leads to increased cell survival, decreased DNA repair capacity, and genomic instability in mouse testicular Leydig cells. Cancer Lett. 2009 Jun 28; 279(1):84-92.
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Millena AC, Reddy SC, Bowling GH, Khan SA. Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha. Mol Cell Endocrinol. 2004 Sep 30; 224(1-2):29-39.
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Chen JJ, Chien EJ, Wang PS. Progesterone attenuates the inhibitory effects of cardiotonic digitalis on pregnenolone production in rat luteal cells. J Cell Biochem. 2002; 86(1):107-17.
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Jenab S, Morris PL. Interleukin-6 regulation of kappa opioid receptor gene expression in primary sertoli cells. Endocrine. 2000 Aug; 13(1):11-5.
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Mack SO, Garrett WM, Guthrie HD. Absence of correlation between in situ expression of cytochrome P450 17alpha hydroxylase/lyase and 3beta-hydroxysteroid dehydrogenase/(Delta5-4) isomerase messenger ribonucleic acids and steroidogenesis during pubertal development in the rat testis. J Steroid Biochem Mol Biol. 2000 May; 73(1-2):19-28.
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Tashima LS, Hieber AD, Greenwood FC, Bryant-Greenwood GD. The human Leydig insulin-like (hLEY I-L) gene is expressed in the corpus luteum and trophoblast. J Clin Endocrinol Metab. 1995 Feb; 80(2):707-10.