"Immunoglobulin Idiotypes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Unique genetically-controlled determinants present on ANTIBODIES whose specificity is limited to a single group of proteins (e.g., another antibody molecule or an individual myeloma protein). The idiotype appears to represent the antigenicity of the antigen-binding site of the antibody and to be genetically codetermined with it. The idiotypic determinants have been precisely located to the IMMUNOGLOBULIN VARIABLE REGION of both immunoglobin polypeptide chains.
| Descriptor ID |
D007130
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| MeSH Number(s) |
D12.644.541.500.745 D12.776.124.486.485.680.745 D12.776.124.790.651.680.745 D12.776.377.715.548.680.745 D23.050.550.750 G02.111.570.060.425.580 G12.500.450
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| Concept/Terms |
Immunoglobulin Idiotypes- Immunoglobulin Idiotypes
- Idiotype, Immunoglobulin
- Immunoglobulin Idiotype
- Idiotypes, Immunoglobulin
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Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Idiotypes".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Idiotypes".
This graph shows the total number of publications written about "Immunoglobulin Idiotypes" by people in this website by year, and whether "Immunoglobulin Idiotypes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoglobulin Idiotypes" by people in Profiles.
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Spatz L, Iliev A, Saenko V, Jones L, Irigoyen M, Manheimer-Lory A, Gaynor B, Putterman C, Bynoe M, Kowal C, Kuo P, Newman J, Diamond B. Studies on the structure, regulation, and pathogenic potential of anti-dsDNA antibodies. Methods. 1997 Jan; 11(1):70-8.
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Teale JM, Landreth KS. Effect of growth and differentiation stimuli on the development of antigen-responsive B cells in fetal liver. Cell Immunol. 1988 Dec; 117(2):389-98.
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Teale JM, Kearney JF. Clonotypic analysis of the fetal B cell repertoire: evidence for an early and predominant expression of idiotypes associated with the VH 36-60 family. J Mol Cell Immunol. 1986; 2(5):283-92.
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Teale JM. Abnormalities in isotype expression in CBA/N mice due to stimulatory environment rather than a B cell defect. J Immunol. 1983 Jan; 130(1):72-7.
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Teale JM, Mackay IR. Autoimmune disease and the theory of clonal abortion. Is it still relevant? Lancet. 1979 Aug 11; 2(8137):284-7.