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Mariana Gerschenson, PhD

TitleAssociate Dean for Research, Director of COBRE-Diabetes
Faculty RankProfessor
InstitutionUniversity of Hawaii
DepartmentDean's Office, Cell and Molecular Biology
AddressJohn A. Burns School of Medicine
University of Hawaii at Manoa
651 Ilalo Street
Honolulu HI 96816
Phone8084411573
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    R01AI074554     (GERSCHENSON, MARIANA)Feb 1, 2008 - Jan 31, 2015
    NIH
    Global HIV Drug Therapies and Mitochondrial Complications and Mechanisms
    Role: Principal Investigator
    R01NR012885     (MILLER, TRACIE L)Sep 28, 2010 - Jun 30, 2016
    NIH
    Mitochondrial Determinants of Metabolic Disease in HIV-Infected Children
    Role: Co-Principal Investigator
    P20GM113134     (GERSCHENSON, MARIANA)Aug 1, 2017 - Jul 31, 2022
    NIH
    COBRE-DIABETES
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gojanovich GS, Yu W, Zhang ZJ, Jacobson DL, Yao TJ, Jao J, Libutti DE, Geffner ME, Gerschenson M. Longitudinal changes in mitochondrial-associated measures and insulin resistance in youth with perinatally-acquired HIV in the U.S. Mitochondrion. 2024 Jul 14; 78:101936. PMID: 39009104.
      Citations:    Fields:    
    2. Jao J, Bonner LB, Dobinda K, Powis KM, Sun S, Legbedze J, Mmasa KN, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Abrams EJ, Kurland IJ, Geffner ME. Lower Insulin Sensitivity Through 36 Months of Life With in Utero HIV and Antiretroviral Exposure in Botswana: Results From the Tshilo Dikotla Study. Clin Infect Dis. 2024 Mar 26. PMID: 38531012.
      Citations:    Fields:    
    3. Torigoe TH, Willcox DC, Shimabukuro M, Higa M, Gerschenson M, Andrukhiv A, Suzuki M, Morris BJ, Chen R, Gojanovich GS, Allsopp RC, Willcox BJ. Novel protective effect of the FOXO3 longevity genotype on mechanisms of cellular aging in Okinawans. NPJ Aging. 2024 Mar 08; 10(1):18. PMID: 38459055.
      Citations:    
    4. Dirajlal-Fargo S, Maison DP, Durieux JC, Andrukhiv A, Funderburg N, Ailstock K, Gerschenson M, Mccomsey GA. Altered mitochondrial respiration in peripheral blood mononuclear cells of post-acute sequelae of SARS-CoV-2 infection. Mitochondrion. 2024 Mar; 75:101849. PMID: 38341012.
      Citations:    Fields:    Translation:HumansCells
    5. Kaur H, Minchella P, Alvarez-Carbonell D, Purandare N, Nagampalli VK, Blankenberg D, Hulgan T, Gerschenson M, Karn J, Aras S, Kallianpur AR. Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells. Int J Mol Sci. 2023 Jul 31; 24(15). PMID: 37569616.
      Citations: 3     Fields:    Translation:HumansCells
    6. Maison DP, Deng Y, Gerschenson M. SARS-CoV-2 and the host-immune response. Front Immunol. 2023; 14:1195871. PMID: 37404823.
      Citations: 4     Fields:    Translation:HumansCells
    7. Jao J, Sun S, Bonner LB, Legbedze J, Mmasa KN, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Abrams EJ, Kurland IJ, Geffner ME, Powis KM. Lower Insulin Sensitivity in Newborns With In Utero HIV and Antiretroviral Exposure Who Are Uninfected in Botswana. J Infect Dis. 2022 11 28; 226(11):2002-2009. PMID: 36240387.
      Citations: 2     Fields:    Translation:Humans
    8. Ma C, Hoffmann FW, Nunes LG, Urena F, Andrukhiv A, Gerschenson M, Pitts MW, Hoffmann PR. Selenoprotein I deficiency in T cells promotes differentiation into tolerant phenotypes while decreasing Th17 pathology. J Leukoc Biol. 2022 12; 112(6):1387-1397. PMID: 35916034.
      Citations: 2     Fields:    Translation:AnimalsCells
    9. Gojanovich GS, Jacobson DL, Broadwell C, Karalius B, Kirmse B, Geffner ME, Jao J, Van Dyke RB, McFarland EJ, Silio M, Crain M, Gerschenson M. Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C. PLoS One. 2021; 16(12):e0261563. PMID: 34972147.
      Citations:    Fields:    Translation:HumansCells
    10. Jao J, Jacobson DL, Russell JS, Wang J, Yu W, Gojanovich GS, Siminski S, Hyzy L, Geffner ME, Gerschenson M. Perinatally acquired HIV infection is associated with abnormal blood mitochondrial function during childhood/adolescence. AIDS. 2021 07 15; 35(9):1385-1394. PMID: 33730749.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    11. Mmasa KN, Powis K, Sun S, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Legbedze J, Abrams EJ, Kurland IJ, Geffner ME, Jao J. Gestational diabetes in women living with HIV in Botswana: lower rates with dolutegravir- than with efavirenz-based antiretroviral therapy. HIV Med. 2021 09; 22(8):715-722. PMID: 34003565.
      Citations: 6     Fields:    Translation:Humans
    12. Gangcuangco LMA, Mitchell BI, Siriwardhana C, Kohorn LB, Chew GM, Bowler S, Kallianpur KJ, Chow DC, Ndhlovu LC, Gerschenson M, Shikuma CM. Correction: Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation. PLoS One. 2021; 16(3):e0249428. PMID: 33765089.
      Citations: 1     Fields:    
    13. Ma C, Hoffmann FW, Marciel MP, Page KE, Williams-Aduja MA, Akana ENL, Gojanovich GS, Gerschenson M, Urschitz J, Moisyadi S, Khadka VS, Rozovsky S, Deng Y, Horgen FD, Hoffmann PR. Upregulated ethanolamine phospholipid synthesis via selenoprotein I is required for effective metabolic reprogramming during T cell activation. Mol Metab. 2021 05; 47:101170. PMID: 33484950.
      Citations: 14     Fields:    Translation:AnimalsCells
    14. Chew GM, Padua AJP, Chow DC, Souza SA, Clements DM, Corley MJ, Pang APS, Alejandria MM, Gerschenson M, Shikuma CM, Ndhlovu LC. Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade. AIDS Res Hum Retroviruses. 2021 01; 37(1):24-33. PMID: 33019813.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    15. Gojanovich GS, Jacobson DL, Jao J, Russell JS, Van Dyke RB, Libutti DE, Sharma TS, Geffner ME, Gerschenson M. Mitochondrial Dysfunction and Insulin Resistance in Pubertal Youth Living with Perinatally Acquired HIV. AIDS Res Hum Retroviruses. 2020 09; 36(9):703-711. PMID: 32586116.
      Citations: 4     Fields:    Translation:HumansCells
    16. Gangcuangco LMA, Mitchell BI, Siriwardhana C, Kohorn LB, Chew GM, Bowler S, Kallianpur KJ, Chow DC, Ndhlovu LC, Gerschenson M, Shikuma CM. Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation. PLoS One. 2020; 15(4):e0231761. PMID: 32353005.
      Citations: 11     Fields:    Translation:HumansCells
    17. Panee J, Pomozi V, Franke AA, Le Saux O, Gerschenson M. Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition. Mitochondrion. 2020 05; 52:135-143. PMID: 32169611.
      Citations: 1     Fields:    Translation:HumansCells
    18. Shikuma CM, Chew GM, Kohorn L, Souza SA, Chow D, SahBandar IN, Park EY, Hanks N, Gangcuangco LMA, Gerschenson M, Ndhlovu LC. Short Communication: Metformin Reduces CD4 T Cell Exhaustion in HIV-Infected Adults on Suppressive Antiretroviral Therapy. AIDS Res Hum Retroviruses. 2020 04; 36(4):303-305. PMID: 31731885.
      Citations: 17     Fields:    Translation:HumansCells
    19. Kallianpur KJ, Walker M, Gerschenson M, Shikuma CM, Gangcuangco LMA, Kohorn L, Libutti DE, Nir TM, Jahanshad N, Thompson PM, Paul R. Systemic Mitochondrial Oxidative Phosphorylation Protein Levels Correlate with Neuroimaging Measures in Chronically HIV-Infected Individuals. AIDS Res Hum Retroviruses. 2020 01; 36(1):83-91. PMID: 31617381.
      Citations: 5     Fields:    Translation:HumansCells
    20. Gojanovich GS, Shikuma CM, Milne C, Libutti DE, Chow DC, Gerschenson M. Subcutaneous Adipocyte Adenosine Triphosphate Levels in HIV Infected Patients. AIDS Res Hum Retroviruses. 2020 01; 36(1):75-82. PMID: 31407586.
      Citations: 1     Fields:    Translation:HumansCells
    21. Hulgan T, Ramsey BS, Koethe JR, Samuels DC, Gerschenson M, Libutti DE, Sax PE, Daar ES, McComsey GA, Brown TT. Relationships Between Adipose Mitochondrial Function, Serum Adiponectin, and Insulin Resistance in Persons With HIV After 96 Weeks of Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2019 03 01; 80(3):358-366. PMID: 30531304.
      Citations: 5     Fields:    Translation:HumansCells
    22. Kallianpur AR, Gerschenson M, Hulgan T, Kaur H, Clifford DB, Haas DW, Murdock DG, McArthur JC, Samuels DC, Simpson DM. Hemochromatosis (HFE) Gene Variants Are Associated with Increased Mitochondrial DNA Levels During HIV-1 Infection and Antiretroviral Therapy. AIDS Res Hum Retroviruses. 2018 11; 34(11):942-949. PMID: 29968489.
      Citations: 2     Fields:    Translation:HumansCells
    23. Geffner ME, Patel K, Jacobson DL, Wu J, Miller TL, Hazra R, Gerschenson M, Sharma T, Silio M, Jao J, Takemoto JK, Van Dyke RB, DiMeglio LA. Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents. AIDS. 2018 03 13; 32(5):613-622. PMID: 29280758.
      Citations: 14     Fields:    Translation:Humans
    24. Berry M, Chen J, Hixon A, Gerschenson M, James N, Jameson D, Lew HL, Lozanoff S, Nichols R, Seifried S, Teshima D, Masaki K, Tam E, Ward B, Ward S. Medical School Hotline: School of Medicine Departments - Year in Review 2017, Part 1. Hawaii J Med Public Health. 2018 01; 77(1):14-16. PMID: 29333336.
      Citations:    Fields:    Translation:Humans
    25. Panee J, Gerschenson M, Chang L. Associations Between Microbiota, Mitochondrial Function, and Cognition in Chronic Marijuana Users. J Neuroimmune Pharmacol. 2018 03; 13(1):113-122. PMID: 29101632.
      Citations: 23     Fields:    Translation:HumansCells
    26. Taylor BS, So-Armah K, Tate JP, Marconi VC, Koethe JR, Bedimo RJ, Butt AA, Gibert CL, Goetz MB, Rodriguez-Barradas MC, Womack JA, Gerschenson M, Lo Re V, Rimland D, Yin MT, Leaf D, Tracy RP, Justice AC, Freiberg MS. HIV and Obesity Comorbidity Increase Interleukin 6 but Not Soluble CD14 or D-Dimer. J Acquir Immune Defic Syndr. 2017 08 15; 75(5):500-508. PMID: 28696344.
      Citations: 9     Fields:    Translation:Humans
    27. Kocher M, McDermott M, Lindsey R, Shikuma CM, Gerschenson M, Chow DC, Kohorn LB, Hetzler RK, Kimura IF. Short Communication: HIV Patient Systemic Mitochondrial Respiration Improves with Exercise. AIDS Res Hum Retroviruses. 2017 Oct; 33(10):1035-1037. PMID: 28467726.
      Citations: 4     Fields:    Translation:HumansCells
    28. Willcox BJ, Morris BJ, Tranah GJ, Chen R, Masaki KH, He Q, Willcox DC, Allsopp RC, Moisyadi S, Gerschenson M, Davy PMC, Poon LW, Rodriguez B, Newman AB, Harris TB, Cummings SR, Liu Y, Parimi N, Evans DS, Donlon TA. Longevity-Associated FOXO3 Genotype and its Impact on Coronary Artery Disease Mortality in Japanese, Whites, and Blacks: A Prospective Study of Three American Populations. J Gerontol A Biol Sci Med Sci. 2017 May 01; 72(5):724-728. PMID: 27694344.
      Citations: 23     Fields:    Translation:Humans
    29. Takemoto JK, Miller TL, Wang J, Jacobson DL, Geffner ME, Van Dyke RB, Gerschenson M. Insulin resistance in HIV-infected youth is associated with decreased mitochondrial respiration. AIDS. 2017 01 02; 31(1):15-23. PMID: 27755108.
      Citations: 19     Fields:    Translation:HumansCells
    30. So-Armah KA, Tate JP, Chang CH, Butt AA, Gerschenson M, Gibert CL, Leaf D, Rimland D, Rodriguez-Barradas MC, Budoff MJ, Samet JH, Kuller LH, Deeks SG, Crothers K, Tracy RP, Crane HM, Sajadi MM, Tindle HA, Justice AC, Freiberg MS. Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People? J Acquir Immune Defic Syndr. 2016 06 01; 72(2):206-213. PMID: 27824677.
      Citations: 47     Fields:    Translation:HumansCells
    31. Willcox BJ, Tranah GJ, Chen R, Morris BJ, Masaki KH, He Q, Willcox DC, Allsopp RC, Moisyadi S, Poon LW, Rodriguez B, Newman AB, Harris TB, Cummings SR, Liu Y, Parimi N, Evans DS, Davy P, Gerschenson M, Donlon TA. The FoxO3 gene and cause-specific mortality. Aging Cell. 2016 08; 15(4):617-24. PMID: 27071935.
      Citations: 35     Fields:    Translation:Humans
    32. Kallianpur KJ, Gerschenson M, Mitchell BI, LiButti DE, Umaki TM, Ndhlovu LC, Nakamoto BK, Chow DC, Shikuma CM. Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients. Mitochondrion. 2016 05; 28:8-15. PMID: 26923169.
      Citations: 23     Fields:    Translation:HumansCells
    33. Lipshultz SE, Anderson LM, Miller TL, Gerschenson M, Stevenson KE, Neuberg DS, Franco VI, LiButti DE, Silverman LB, Vrooman LM, Sallan SE. Impaired mitochondrial function is abrogated by dexrazoxane in doxorubicin-treated childhood acute lymphoblastic leukemia survivors. Cancer. 2016 Mar 15; 122(6):946-53. PMID: 26762648.
      Citations: 20     Fields:    Translation:HumansCells
    34. Shikuma CM, Bennett K, Ananworanich J, Gerschenson M, Teeratakulpisarn N, Jadwattanakul T, DeGruttola V, McArthur JC, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiat P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N. Distal leg epidermal nerve fiber density as a surrogate marker of HIV-associated sensory neuropathy risk: risk factors and change following initial antiretroviral therapy. J Neurovirol. 2015 Oct; 21(5):525-34. PMID: 26002840.
      Citations: 4     Fields:    Translation:HumansCells
    35. Berry MJ, Astern J, Bellinger F, Brampton C, Cann R, Gerschenson M, Haymer D, James NG, Jameson DM, LeSaux O, Hoffmann PR, Nichols R, Pitts M, Seale L, Seifried S, Stokes AJ, Todorovic C. Medical school hotline: the research mission of the cell and molecular biology department and program at the john a. Burns school of medicine. Hawaii J Med Public Health. 2015 Apr; 74(4):150-3. PMID: 25954603.
      Citations:    Fields:    Translation:Humans
    36. Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM. Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort. Atherosclerosis. 2015 Mar; 239(1):50-4. PMID: 25574857.
      Citations: 11     Fields:    Translation:HumansCells
    37. Hulgan T, Levinson RT, Gerschenson M, Phanuphak N, Ananworanich J, Teeratakulpisarm N, Jadwattanakul T, LiButti DE, Fink H, McArthur JC, Ebenezer GJ, Hauer P, Murdock D, Shikuma CM, Samuels DC. Epidermal nerve fiber density, oxidative stress, and mitochondrial haplogroups in HIV-infected Thais initiating therapy. AIDS. 2014 Jul 17; 28(11):1625-33. PMID: 24785954.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    38. Shikuma CM, Gangcuangco LM, Killebrew DA, Libutti DE, Chow DC, Nakamoto BK, Liang CY, Milne CI, Ndhlovu LC, Barbour JD, Shiramizu BT, Gerschenson M. The role of HIV and monocytes/macrophages in adipose tissue biology. J Acquir Immune Defic Syndr. 2014 Feb 01; 65(2):151-9. PMID: 24091690.
      Citations: 27     Fields:    Translation:HumansCells
    39. Sharma TS, Jacobson DL, Anderson L, Gerschenson M, Van Dyke RB, McFarland EJ, Miller TL. Short communication: The relationship between mitochondrial dysfunction and insulin resistance in HIV-infected children receiving antiretroviral therapy. AIDS Res Hum Retroviruses. 2013 Sep; 29(9):1211-7. PMID: 23742635.
      Citations: 12     Fields:    Translation:HumansCells
    40. Hulgan T, Stein JH, Cotter BR, Murdock DG, Ritchie MD, Dube MP, Gerschenson M, Haas DW, Torriani FJ. Mitochondrial DNA variation and changes in adiponectin and endothelial function in HIV-infected adults after antiretroviral therapy initiation. AIDS Res Hum Retroviruses. 2013 Oct; 29(10):1293-9. PMID: 23944767.
      Citations: 10     Fields:    Translation:Humans
    41. Phanuphak N, Ananworanich J, Teeratakulpisarn N, Jadwattanakul T, Kerr SJ, Chomchey N, Hongchookiat P, Mathajittiphun P, Pinyakorn S, Rungrojrat P, Praihirunyakit P, Gerschenson M, Phanuphak P, Valcour V, Kim JH, Shikuma C. A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine. Antivir Ther. 2012; 17(8):1521-31. PMID: 23220732.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    42. McComsey GA, Daar ES, O'Riordan M, Collier AC, Kosmiski L, Santana JL, Fichtenbaum CJ, Fink H, Sax PE, Libutti DE, Gerschenson M. Changes in fat mitochondrial DNA and function in subjects randomized to abacavir-lamivudine or tenofovir DF-emtricitabine with atazanavir-ritonavir or efavirenz: AIDS Clinical Trials Group study A5224s, substudy of A5202. J Infect Dis. 2013 Feb 15; 207(4):604-11. PMID: 23204164.
      Citations: 30     Fields:    Translation:HumansCells
    43. Shikuma C, Gerschenson M, Ananworanich J, Valcour V, Teeratakulpisarn N, Jadwattanakul T, Degruttola V, Liang CY, McArthur J, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiath P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N. Determinants of epidermal nerve fibre density in antiretroviral-na?ve HIV-infected individuals. HIV Med. 2012 Nov; 13(10):602-8. PMID: 22574621.
      Citations: 5     Fields:    Translation:HumansCells
    44. Armah KA, McGinnis K, Baker J, Gibert C, Butt AA, Bryant KJ, Goetz M, Tracy R, Oursler KK, Rimland D, Crothers K, Rodriguez-Barradas M, Crystal S, Gordon A, Kraemer K, Brown S, Gerschenson M, Leaf DA, Deeks SG, Rinaldo C, Kuller LH, Justice A, Freiberg M. HIV status, burden of comorbid disease, and biomarkers of inflammation, altered coagulation, and monocyte activation. Clin Infect Dis. 2012 Jul; 55(1):126-36. PMID: 22534147.
      Citations: 127     Fields:    Translation:HumansCells
    45. Hulgan T, Gerschenson M. HIV and mitochondria: more than just drug toxicity. J Infect Dis. 2012 Jun 15; 205(12):1769-71. PMID: 22476715.
      Citations: 16     Fields:    Translation:HumansCells
    46. Shikuma CM, Seto T, Liang CY, Bennett K, DeGruttola V, Gerschenson M, Stein JH, Budoff M, Hodis HN, Delaney JA, Ogata-Arakaki D, Pramyothin P, Chow D. Vitamin D levels and markers of arterial dysfunction in HIV. AIDS Res Hum Retroviruses. 2012 Aug; 28(8):793-7. PMID: 21978287.
      Citations: 33     Fields:    Translation:Humans
    47. McComsey GA, O'Riordan M, Choi J, Libutti D, Rowe D, Storer N, Harrill D, Gerschenson M. Mitochondrial function, inflammation, fat and bone in HIV lipoatrophy: randomized study of uridine supplementation or switch to tenofovir. Antivir Ther. 2012; 17(2):347-53. PMID: 22293126.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    48. Chow DC, Wood R, Choi J, Grandinetti A, Gerschenson M, Sriratanaviriyakul N, Nakamoto B, Shikuma C, Low P. Cardiovagal autonomic function in HIV-infected patients with unsuppressed HIV viremia. HIV Clin Trials. 2011 May-Jun; 12(3):141-50. PMID: 21684854.
      Citations: 16     Fields:    Translation:Humans
    49. C?t? HC, Gerschenson M, Walker UA, Miro O, Garrabou G, Hammond E, Villarroya J, Giralt M, Villarroya F, Cinque P, Garcia-Arumi E, Andreu AL, Pinti M, Cossarizza A. Quality assessment of human mitochondrial DNA quantification: MITONAUTS, an international multicentre survey. Mitochondrion. 2011 May; 11(3):520-7. PMID: 21303702.
      Citations: 13     Fields:    Translation:HumansCells
    50. Brogly SB, DiMauro S, Van Dyke RB, Williams PL, Naini A, Libutti DE, Choi J, Chung M, Gerschenson M. Short communication: transplacental nucleoside analogue exposure and mitochondrial parameters in HIV-uninfected children. AIDS Res Hum Retroviruses. 2011 Jul; 27(7):777-83. PMID: 21142587.
      Citations: 20     Fields:    Translation:HumansCells
    51. Chow DC, Stein JH, Seto TB, Mitchell C, Sriratanaviriyakul N, Grandinetti A, Gerschenson M, Shiramizu B, Souza S, Shikuma C. Short-term effects of extended-release niacin on endothelial function in HIV-infected patients on stable antiretroviral therapy. AIDS. 2010 Apr 24; 24(7):1019-23. PMID: 20216298.
      Citations: 8     Fields:    Translation:HumansCells
    52. Tungsiripat M, O'Riordan MA, Storer N, Harrill D, Ganz J, Libutti D, Gerschenson M, McComsey GA. Subjective clinical lipoatrophy assessment correlates with DEXA-measured limb fat. HIV Clin Trials. 2009 Sep-Oct; 10(5):314-9. PMID: 19906628.
      Citations: 3     Fields:    Translation:HumansCells
    53. Gerschenson M, Kim C, Berzins B, Taiwo B, Libutti DE, Choi J, Chen D, Weinstein J, Shore J, da Silva B, Belsey E, McComsey GA, Murphy RL. Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen. J Antimicrob Chemother. 2009 Jun; 63(6):1244-50. PMID: 19321503.
      Citations: 22     Fields:    Translation:HumansCells
    54. Valcour V, Yeh TM, Bartt R, Clifford D, Gerschenson M, Evans SR, Cohen BA, Ebenezer GJ, Hauer P, Millar L, Gould M, Tran P, Shikuma C, Souza S, McArthur JC. Acetyl-l-carnitine and nucleoside reverse transcriptase inhibitor-associated neuropathy in HIV infection. HIV Med. 2009 Feb; 10(2):103-10. PMID: 19200173.
      Citations: 11     Fields:    Translation:HumansCells
    55. Stein JH, Komarow L, Cotter BR, Currier JS, Dub? MP, Fichtenbaum CJ, Gerschenson M, Mitchell CK, Murphy RL, Squires K, Parker RA, Torriani FJ. Lipoprotein Changes in HIV-Infected Antiretroviral-Na?ve Individuals after Starting Antiretroviral Therapy: ACTG Study A5152s Stein: Lipoprotein Changes on Antiretroviral Therapy. J Clin Lipidol. 2008 Dec; 2(6):464-471. PMID: 19956354.
      Citations: 13     Fields:    
    56. Shikuma CM, Gerschenson M, Chow D, Libutti DE, Willis JH, Murray J, Capaldi RA, Marusich M. Mitochondrial oxidative phosphorylation protein levels in peripheral blood mononuclear cells correlate with levels in subcutaneous adipose tissue within samples differing by HIV and lipoatrophy status. AIDS Res Hum Retroviruses. 2008 Oct; 24(10):1255-62. PMID: 18844460.
      Citations: 14     Fields:    Translation:HumansCells
    57. Torriani FJ, Komarow L, Parker RA, Cotter BR, Currier JS, Dub? MP, Fichtenbaum CJ, Gerschenson M, Mitchell CK, Murphy RL, Squires K, Stein JH. Endothelial function in human immunodeficiency virus-infected antiretroviral-naive subjects before and after starting potent antiretroviral therapy: The ACTG (AIDS Clinical Trials Group) Study 5152s. J Am Coll Cardiol. 2008 Aug 12; 52(7):569-76. PMID: 18687253.
      Citations: 154     Fields:    Translation:HumansCells
    58. McComsey GA, Libutti DE, O'Riordan M, Shelton JM, Storer N, Ganz J, Jasper J, Harrill D, Gerschenson M. Mitochondrial RNA and DNA alterations in HIV lipoatrophy are linked to antiretroviral therapy and not to HIV infection. Antivir Ther. 2008; 13(5):715-22. PMID: 18771055.
      Citations: 16     Fields:    Translation:HumansCells
    59. Zhou L, Kitch DW, Evans SR, Hauer P, Raman S, Ebenezer GJ, Gerschenson M, Marra CM, Valcour V, Diaz-Arrastia R, Goodkin K, Millar L, Shriver S, Asmuth DM, Clifford DB, Simpson DM, McArthur JC. Correlates of epidermal nerve fiber densities in HIV-associated distal sensory polyneuropathy. Neurology. 2007 Jun 12; 68(24):2113-9. PMID: 17562831.
      Citations: 39     Fields:    Translation:HumansCells
    60. Simpson DM, Kitch D, Evans SR, McArthur JC, Asmuth DM, Cohen B, Goodkin K, Gerschenson M, So Y, Marra CM, Diaz-Arrastia R, Shriver S, Millar L, Clifford DB. HIV neuropathy natural history cohort study: assessment measures and risk factors. Neurology. 2006 Jun 13; 66(11):1679-87. PMID: 16769940.
      Citations: 73     Fields:    Translation:HumansCTClinical Trials
    61. Shikuma CM, Day LJ, Gerschenson M. Insulin resistance in the HIV-infected population: the potential role of mitochondrial dysfunction. Curr Drug Targets Infect Disord. 2005 Sep; 5(3):255-62. PMID: 16181144.
      Citations: 20     Fields:    Translation:Humans
    62. Shikuma CM, Valcour VG, Ratto-Kim S, Williams AE, Souza S, Gerschenson M, Day L, Kim JH, Shiramizu B. HIV-associated wasting in the era of highly active antiretroviral therapy: a syndrome of residual HIV infection in monocytes and macrophages? Clin Infect Dis. 2005 Jun 15; 40(12):1846-8. PMID: 15909275.
      Citations: 5     Fields:    Translation:HumansCells
    63. Gerschenson M, Shiramizu B, LiButti DE, Shikuma CM. Mitochondrial DNA levels of peripheral blood mononuclear cells and subcutaneous adipose tissue from thigh, fat and abdomen of HIV-1 seropositive and negative individuals. Antivir Ther. 2005; 10 Suppl 2:M83-9. PMID: 16152709.
      Citations: 20     Fields:    Translation:HumansCells
    64. Day L, Shikuma C, Gerschenson M. Acetyl-L-carnitine for the treatment of HIV lipoatrophy. Ann N Y Acad Sci. 2004 Nov; 1033:139-46. PMID: 15591011.
      Citations:    Fields:    Translation:HumansCells
    65. Gerschenson M, Brinkman K. Mitochondrial dysfunction in AIDS and its treatment. Mitochondrion. 2004 Sep; 4(5-6):763-77. PMID: 16120431.
      Citations: 25     Fields:    
    66. Day L, Shikuma C, Gerschenson M. Mitochondrial injury in the pathogenesis of antiretroviral-induced hepatic steatosis and lactic acidemia. Mitochondrion. 2004 Jul; 4(2-3):95-109. PMID: 16120375.
      Citations: 5     Fields:    
    67. Kamemoto LE, Shiramizu B, Gerschenson M. HIV-associated mitochondrial toxicity in pregnancy. Mitochondrion. 2004 Jul; 4(2-3):153-62. PMID: 16120380.
      Citations: 2     Fields:    
    68. Walsh EJ, Souza S, Gerschenson M, Shikuma C, Chow D. HIV disease progression and limited antiretroviral treatment options for a HIV-1 infected individual with myoclonic epilepsy associated with ragged red fibers. Mitochondrion. 2004 Jul; 4(2-3):169-73. PMID: 16120382.
      Citations:    Fields:    
    69. Gerschenson M, Nguyen V, Ewings EL, Ceresa A, Shaw JA, St Claire MC, Nagashima K, Harbaugh SW, Harbaugh JW, Olivero OA, Divi RL, Albert PS, Poirier MC. Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine. AIDS Res Hum Retroviruses. 2004 Jan; 20(1):91-100. PMID: 15000702.
      Citations: 16     Fields:    Translation:AnimalsCells
    70. Gerschenson M. Mitochondria and lipodystrophy: where are we now? Antivir Ther. 2003 Aug; 8(4):261-3. PMID: 14518694.
      Citations: 1     Fields:    Translation:HumansCells
    71. Shiramizu B, Shikuma KM, Kamemoto L, Gerschenson M, Erdem G, Pinti M, Cossarizza A, Shikuma C. Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy. J Acquir Immune Defic Syndr. 2003 Apr 01; 32(4):370-4. PMID: 12640193.
      Citations: 32     Fields:    Translation:HumansCellsPHPublic Health
    72. Dagan T, Sable C, Bray J, Gerschenson M. Mitochondrial dysfunction and antiretroviral nucleoside analog toxicities: what is the evidence? Mitochondrion. 2002 May; 1(5):397-412. PMID: 16120293.
      Citations: 26     Fields:    
    73. Low RL, Gerschenson M. Endonuclease G isolation and assays. Methods Mol Biol. 2002; 197:331-49. PMID: 12013808.
      Citations:    Fields:    Translation:AnimalsCells
    74. Gerschenson M, Nguyen VT, St Claire MC, Harbaugh SW, Harbaugh JW, Proia LA, Poirier MC. Chronic stavudine exposure induces hepatic mitochondrial toxicity in adult Erythrocebus patas monkeys. J Hum Virol. 2001 Nov-Dec; 4(6):335-42. PMID: 12082400.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    75. Gerschenson M, Paik CY, Gaukler EL, Diwan BA, Poirier MC. Cisplatin exposure induces mitochondrial toxicity in pregnant rats and their fetuses. Reprod Toxicol. 2001 Sep-Oct; 15(5):525-31. PMID: 11780959.
      Citations: 4     Fields:    Translation:AnimalsCells
    76. DasGupta SF, Rapoport SI, Gerschenson M, Murphy E, Fiskum G, Russell SJ, Chandrasekaran K. ATP synthesis is coupled to rat liver mitochondrial RNA synthesis. Mol Cell Biochem. 2001 May; 221(1-2):3-10. PMID: 11506183.
      Citations: 2     Fields:    Translation:AnimalsCells
    77. Gerschenson M, Poirier MC. Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure. Ann N Y Acad Sci. 2000 Nov; 918:269-81. PMID: 11131713.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    78. Ewings EL, Gerschenson M, St Claire MC, Nagashima K, Skopets B, Harbaugh SW, Harbaugh JW, Poirier MC. Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria. J Acquir Immune Defic Syndr. 2000 Jun 01; 24(2):100-5. PMID: 10935684.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    79. Gerschenson M, Erhart SW, Paik CY, St Claire MC, Nagashima K, Skopets B, Harbaugh SW, Harbaugh JW, Quan W, Poirier MC. Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine. AIDS Res Hum Retroviruses. 2000 May 01; 16(7):635-44. PMID: 10791874.
      Citations: 21     Fields:    Translation:AnimalsCells
    80. Bialkowska A, Bialkowski K, Gerschenson M, Diwan BA, Jones AB, Olivero OA, Poirier MC, Anderson LM, Kasprzak KS, Sipowicz MA. Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT). Carcinogenesis. 2000 May; 21(5):1059-62. PMID: 10783333.
      Citations: 9     Fields:    Translation:HumansAnimals
    81. Gerschenson M, Houmiel KL, Low RL. Endonuclease G from mammalian nuclei is identical to the major endonuclease of mitochondria. Nucleic Acids Res. 1995 Jan 11; 23(1):88-97. PMID: 7870594.
      Citations: 15     Fields:    Translation:AnimalsCells
    82. Gerschenson M, Low RL, Loehr J. Levels of the mitochondrial endonuclease during rat cardiac development implicate a role for the enzyme in repair of oxidative damage in mitochondrial DNA. J Mol Cell Cardiol. 1994 Jan; 26(1):31-40. PMID: 8196067.
      Citations: 6     Fields:    Translation:AnimalsCells
    83. Houmiel KL, Gerschenson M, Low RL. Mitochondrial endonuclease activity in the rat varies markedly among tissues in relation to the rate of tissue metabolism. Biochim Biophys Acta. 1991 Aug 30; 1079(2):197-202. PMID: 1655036.
      Citations: 5     Fields:    Translation:AnimalsCells
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