TNF Receptor-Associated Death Domain Protein
"TNF Receptor-Associated Death Domain Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 34 kDa signal transducing adaptor protein that associates with TUMOR NECROSIS FACTOR RECEPTOR TYPE 1. It facilitates the recruitment of signaling proteins such as TNF RECEPTOR-ASSOCIATED FACTOR 2 and FAS ASSOCIATED DEATH DOMAIN PROTEIN to the receptor complex.
Descriptor ID |
D053199
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MeSH Number(s) |
D12.644.360.024.285.600 D12.644.360.024.500.249 D12.644.360.075.421.600 D12.776.157.057.018.600 D12.776.157.057.500.249 D12.776.476.024.320.775 D12.776.476.024.500.249 D12.776.476.075.421.600
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TNF Receptor-Associated Death Domain Protein".
Below are MeSH descriptors whose meaning is more specific than "TNF Receptor-Associated Death Domain Protein".
This graph shows the total number of publications written about "TNF Receptor-Associated Death Domain Protein" by people in this website by year, and whether "TNF Receptor-Associated Death Domain Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 1 | 1 |
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Below are the most recent publications written about "TNF Receptor-Associated Death Domain Protein" by people in Profiles.
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Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clin Cancer Res. 2006 Mar 15; 12(6):1828-38.