Transcription Factor RelA

"Transcription Factor RelA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subunit of NF-kappa B that is primarily responsible for its transactivation function. It contains a C-terminal transactivation domain and an N-terminal domain with homology to PROTO-ONCOGENE PROTEINS C-REL.

Descriptor ID	D051996
MeSH Number(s)	D12.776.260.600.249 D12.776.660.600.249 D12.776.930.600.249
Concept/Terms	Transcription Factor RelA Transcription Factor RelA RelA, Transcription Factor NF-kappa B p65 NF kappa B p65 p65, NF-kappa B NF-kappa B p65 Subunit NF kappa B p65 Subunit Transcription Factor p65 p65, Transcription Factor p65 Transcription Factor Transcription Factor, p65 v-Rel Reticuloendotheliosis Viral Oncogene Homolog A v Rel Reticuloendotheliosis Viral Oncogene Homolog A NF-kappaB 65-kDa NF kappaB 65 kDa

Below are MeSH descriptors whose meaning is more general than "Transcription Factor RelA".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
NF-kappa B [D12.776.260.600]
Transcription Factor RelA [D12.776.260.600.249]
Nuclear Proteins [D12.776.660]
NF-kappa B [D12.776.660.600]
Transcription Factor RelA [D12.776.660.600.249]
Transcription Factors [D12.776.930]
NF-kappa B [D12.776.930.600]
Transcription Factor RelA [D12.776.930.600.249]

Below are MeSH descriptors whose meaning is related to "Transcription Factor RelA".

Below are MeSH descriptors whose meaning is more specific than "Transcription Factor RelA".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transcription Factor RelA" by people in this website by year, and whether "Transcription Factor RelA" was a major or minor topic of these publications.

Bar chart showing 38 publications over 21 distinct years, with a maximum of 4 publications in 2004 and 2014 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2001	0	1	1
2002	0	1	1
2003	0	3	3
2004	0	4	4
2005	0	1	1
2006	2	0	2
2008	1	1	2
2009	0	1	1
2010	0	2	2
2011	0	1	1
2014	1	3	4
2015	1	1	2
2016	1	3	4
2017	1	1	2
2018	1	0	1
2020	1	0	1
2021	1	0	1
2022	0	1	1
2024	0	2	2
2025	1	0	1

Below are the most recent publications written about "Transcription Factor RelA" by people in Profiles.

Okeoma BC, Kaddour H, Naushad W, Paromov V, Chaudhary A, Noghero A, Stapleton JT, Okeoma CM. Identification of proteins in semen-derived extracellular vesicles that bind to Tat and NF-?B and that may impair HIV replication. Sci Signal. 2025 Sep 09; 18(903):eado9243.

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Zhu N, Rogers WE, Heidary DK, Huxford T. Structural and biochemical analyses of the nuclear I?B? protein in complex with the NF-?B p50 homodimer. Genes Dev. 2024 Jul 19; 38(11-12):528-535.

View in: PubMed
Ramar V, Guo S, Hudson B, Khedri A, Guo AA, Li J, Liu M. Interaction of NF-?B and FOSL1 drives glioma stemness. Cell Mol Life Sci. 2024 Jun 10; 81(1):255.

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Rana S, Kour S, Kizhake S, King HM, Mallareddy JR, Case AJ, Huxford T, Natarajan A. Dimers of isatin derived a-methylene-?-butyrolactone as potent anti-cancer agents. Bioorg Med Chem Lett. 2022 06 01; 65:128713.

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Tang TT, Wang B, Li ZL, Wen Y, Feng ST, Wu M, Liu D, Cao JY, Yin Q, Yin D, Fu YQ, Gao YM, Ding ZY, Qian JY, Wu QL, Lv LL, Liu BC. Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI. J Am Soc Nephrol. 2021 10; 32(10):2467-2483.

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Chuang TD, Rehan A, Khorram O. Tranilast induces MiR-200c expression through blockade of RelA/p65 activity in leiomyoma smooth muscle cells. Fertil Steril. 2020 06; 113(6):1308-1318.

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Hu W, Lu H, Zhang J, Fan Y, Chang Z, Liang W, Wang H, Zhu T, Garcia-Barrio MT, Peng D, Chen YE, Guo Y. Kr?ppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-?B signaling pathway. Atherosclerosis. 2018 11; 278:39-48.

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Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G. Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor ?B RelA Subunit. Biochemistry. 2018 05 22; 57(20):2943-2957.

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House CD, Jordan E, Hernandez L, Ozaki M, James JM, Kim M, Kruhlak MJ, Batchelor E, Elloumi F, Cam MC, Annunziata CM. NF?B Promotes Ovarian Tumorigenesis via Classical Pathways That Support Proliferative Cancer Cells and Alternative Pathways That Support ALDH+ Cancer Stem-like Cells. Cancer Res. 2017 12 15; 77(24):6927-6940.

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Zhang QH, Hao JW, Li GL, Ji XJ, Yao XD, Dong N, Yao YM. Proinflammatory switch from Gas to Gai signaling by Glucagon-like peptide-1 receptor in murine splenic monocyte following burn injury. Inflamm Res. 2018 Feb; 67(2):157-168.

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