Cyclin-Dependent Kinase 5
"Cyclin-Dependent Kinase 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine-threonine kinase that plays important roles in CELL DIFFERENTIATION; CELL MIGRATION; and CELL DEATH of NERVE CELLS. It is closely related to other CYCLIN-DEPENDENT KINASES but does not seem to participate in CELL CYCLE regulation.
| Descriptor ID |
D051360
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| MeSH Number(s) |
D08.811.913.696.620.682.700.646.500.500.500 D12.644.360.250.067.875 D12.776.167.200.067.875 D12.776.476.250.067.875
|
| Concept/Terms |
Cyclin-Dependent Kinase 5- Cyclin-Dependent Kinase 5
- Cyclin Dependent Kinase 5
- Neuronal Cdc2-Like Protein Kinase
- Neuronal Cdc2 Like Protein Kinase
- Cdk5 Protein Kinase
- Protein Kinase, Cdk5
- Cdk5 Protein
- PSSALRE Protein
- Cdc2-Related Kinase PSSALRE
- Cdc2 Related Kinase PSSALRE
- PSSALRE, Cdc2-Related Kinase
|
Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase 5".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase 5".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase 5" by people in this website by year, and whether "Cyclin-Dependent Kinase 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase 5" by people in Profiles.
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Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T. Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain Res. 2020 06 01; 1736:146762.
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Zhou L, Sun WL, Weierstall K, Minerly AC, Weiner J, Jenab S, Quinones-Jenab V. Sex differences in behavioral and PKA cascade responses to repeated cocaine administration. Psychopharmacology (Berl). 2016 Oct; 233(19-20):3527-36.
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Ding Y, Qiao A, Wang Z, Goodwin JS, Lee ES, Block ML, Allsbrook M, McDonald MP, Fan GH. Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci. 2008 Nov 05; 28(45):11622-34.
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Liu Y, Ding X, Wang D, Deng H, Feng M, Wang M, Yu X, Jiang K, Ward T, Aikhionbare F, Guo Z, Forte JG, Yao X. A mechanism of Munc18b-syntaxin 3-SNAP25 complex assembly in regulated epithelial secretion. FEBS Lett. 2007 Sep 04; 581(22):4318-24.
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Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. J Neurochem. 2004 Feb; 88(3):554-63.
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Yang HS, Alexander K, Santiago P, Hinds PW. ERM proteins and Cdk5 in cellular senescence. Cell Cycle. 2003 Nov-Dec; 2(6):517-20.
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Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M. Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology. 2002 Feb 26; 58(4):589-92.