"CDC2-CDC28 Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A family of cell cycle-dependent kinases that are related in structure to CDC28 PROTEIN KINASE; S CEREVISIAE; and the CDC2 PROTEIN KINASE found in mammalian species.
    
			
			
				
				
					
						| Descriptor ID | D042846 | 
					
						| MeSH Number(s) | D08.811.913.696.620.682.700.646.500.500 D12.644.360.250.067 D12.776.167.200.067 D12.776.476.250.067 | 
					
						| Concept/Terms | CDC2-CDC28 KinasesCDC2-CDC28 KinasesCDC2 CDC28 KinasesCDC2+-CDC28-related Protein KinaseCDC2+ CDC28 related Protein Kinase
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				Below are MeSH descriptors whose meaning is more general than "CDC2-CDC28 Kinases".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "CDC2-CDC28 Kinases".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "CDC2-CDC28 Kinases" by people in this website by year, and whether "CDC2-CDC28 Kinases" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1999 | 1 | 0 | 1 | 
| 2002 | 2 | 0 | 2 | 
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				Below are the most recent publications written about "CDC2-CDC28 Kinases" by people in Profiles.
						
					
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								Deng L, Ammosova T, Pumfery A, Kashanchi F, Nekhai S. HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter. J Biol Chem. 2002 Sep 13; 277(37):33922-9. 
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								Nekhai S, Zhou M, Fernandez A, Lane WS, Lamb NJ, Brady J, Kumar A. HIV-1 Tat-associated RNA polymerase C-terminal domain kinase, CDK2, phosphorylates CDK7 and stimulates Tat-mediated transcription. Biochem J. 2002 Jun 15; 364(Pt 3):649-57. 
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								Moore JD, Yang J, Truant R, Kornbluth S. Nuclear import of Cdk/cyclin complexes: identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1. J Cell Biol. 1999 Jan 25; 144(2):213-24. 
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								Flores-Rozas H, Kelman Z, Dean FB, Pan ZQ, Harper JW, Elledge SJ, O'Donnell M, Hurwitz J. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc Natl Acad Sci U S A. 1994 Aug 30; 91(18):8655-9.